KR900701288A - 고혈압의 치료 - Google Patents

고혈압의 치료

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Publication number
KR900701288A
KR900701288A KR1019900701332A KR900701332A KR900701288A KR 900701288 A KR900701288 A KR 900701288A KR 1019900701332 A KR1019900701332 A KR 1019900701332A KR 900701332 A KR900701332 A KR 900701332A KR 900701288 A KR900701288 A KR 900701288A
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KR
South Korea
Prior art keywords
potassium
hypertension
salt
human body
patient
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KR1019900701332A
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English (en)
Other versions
KR0178033B1 (ko
Inventor
알. 커티스 제이알 모리스
안토니 세바스챤
Original Assignee
원본미기재
더 리전츠 오브 더 유니버시티 오브 캘리포니아
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Application filed by 원본미기재, 더 리전츠 오브 더 유니버시티 오브 캘리포니아 filed Critical 원본미기재
Publication of KR900701288A publication Critical patent/KR900701288A/ko
Application granted granted Critical
Publication of KR0178033B1 publication Critical patent/KR0178033B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

고혈압의 치료
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본태성 고혈압을 갖는 두명의 남자 환자에게, 각각 15일동안 4회 경구투여로 200mmo1e/70kg 체중/일의 중탄산 칼륨을 투여한 곁과를 나타낸 그래프.
제2도는 5명의 정압성 남성에게 8일동안 1일에 70kg 체중당 약 100mmo1es의 중탄산 칼륨을 투여한 결과를 나타낸 제1도와 유사한 그래프.
제3도는 6명의 폐경후 정압성 여성에 대해 시간에 대한 평균 수축기와 이완기 MAP값에 대한 각각의 그래프로 제1도 및 제2도와 유사한 또 다른 그래프.

Claims (20)

  1. 약리적으로 허용 가능한 비-할로겐 음이온의 칼륨염을 포함하는 조성물의 치료량을 투여함으로 이루어지는, 인체내 고혈압증 치료방법
  2. 제1항에 있어서, 고혈압 환자 또는 고혈압을 일으키기 쉬운 정압성 환자를 상기 칼륨염을 사용하여 치료함으로 이루어지는, 인체내 고혈압증 치료방법.
  3. 제1항에 있어서, 상기 칼륨염은 중탄산 칼륨, 인산칼륨, 글루콘산 칼륨및 시트르산 칼륨으로 이루어진 그룹에서 선택됨을 특징으로 하는 방법.
  4. 제3항에 있어서, 상기 염이 중탄산 칼륨임을 특징으로 하는 방법.
  5. 제3항에 있어서, 칼륨염이 식이 보충물로 투여됨을 특징으로 하는 방법
  6. 중탄산 칼륨을 포함하는 조성물의 치료적 유효량을 투여함으로 이루어지는 인체내 고혈압증 치료방법.
  7. 제6항에 있어서, 고혈압 환자 또는 고혈압을 일으키기 쉬운 정압성 환자를 상기 중탄산 칼륨 조성물을 사용하여 치료함으로 이루어지는 인체내 고혈압중 치료방법.
  8. 제6항에 있어서, 중탄산 칼륨을 경구적으로 투여함을 특징으로 하는 방법.
  9. 제8항에 있어서, 중탄산 칼륨이 식이 보충물로 투여됨을 특징으로 하는 방법.
  10. 제6항에 있어서, 중탄산 칼륨이 약 50-200mmo1es/77kg 체중/24시간의 양으로 투여됨을 특징으로 하는 방법.
  11. 제6항에 있어서, 조성물은 제약적으로 허용 가능한 담체를 포함함을 특징으로 하는 방법.
  12. 중탄산 칼륨 및 인산 칼륨으로 이루어진 그룹에서 선택된 비-할로겐화 칼륨염을 환자의 동맥 혈압을 저하시키기에 충분한 앙으로, 상기 환자에게 투여함으로 이루어지는, 고헐압을 일으키기 쉬운 정압성 환자내 고혈압증의 발생을 방지하는 방법.
  13. 인체의 혈압을 측정하며 제1값을 얻고, 비-할로겐화 칼륨염을 상기 인체에 투여하며, 혈압을 측정하여 제2값을 얻은 후, 제1값과 제2값을 비교하고, 그로부터 상기 인체를 진단함으로 이루어지는 비-할로겐화 칼륨염으로 치료 가능한 고혈압증을 앓고 있는 환자 또는 고혈압에 걸리기 쉬운 인체를 진단하는 방법.
  14. 제13항에 있어서, 비-할로겐화 칼륨염을 비-할로겐화 치료법 또는 예방법에 감응하는 인체내 혈압의 현저한 저하틀 유발시키기에 충분한 양과 시간동안 투여함을 특징으로 하는 방법.
  15. 제14항에 있어서, 인체에 투여되는 비-할로겐화 칼륨염이 중탄산 칼륨임을 특징으로 하는 방법.
  16. 제14항에 있어서, 인체에 투여되는 비-할로겐화 칼륨염이 인산 칼륨임을 특징으로 하는 방법.
  17. 비-할로겐화 칼륨염을 포함하며, 고혈압 환자나 정압성 환자내 고혈압중을 치료하기 위해 상기 염을 사용하는 지시가 프린트된 용기.
  18. 제17항에 있어서, 상기 지시가 용기상에 프린트되어 있음을 특징으로 하는 방법.
  19. 제17항에 있어서, 상기 염이 중탄산 칼륨임을 특징으로 하는 용기.
  20. 제17항에 있어서, 상기 염이 인산 칼륨임을 륵징으로 하는 용기.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900701332A 1988-10-21 1989-10-20 고혈압 치료용 조성물 KR0178033B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26085688A 1988-10-21 1988-10-21
US260,856 1988-10-21

Publications (2)

Publication Number Publication Date
KR900701288A true KR900701288A (ko) 1990-12-01
KR0178033B1 KR0178033B1 (ko) 1999-03-20

Family

ID=22990921

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019900701332A KR0178033B1 (ko) 1988-10-21 1989-10-20 고혈압 치료용 조성물
KR1019900701331A KR0163583B1 (ko) 1988-10-21 1989-10-20 골다공증 치료용 약제 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019900701331A KR0163583B1 (ko) 1988-10-21 1989-10-20 골다공증 치료용 약제 조성물

Country Status (13)

Country Link
US (1) US5804204A (ko)
EP (3) EP0720855A3 (ko)
JP (2) JP2948247B2 (ko)
KR (2) KR0178033B1 (ko)
AT (1) ATE145825T1 (ko)
AU (2) AU635231B2 (ko)
CA (2) CA2001123C (ko)
DE (2) DE68927519T2 (ko)
DK (2) DK175840B1 (ko)
HU (2) HU212106B (ko)
IL (2) IL92076A (ko)
WO (2) WO1990004402A1 (ko)
ZA (2) ZA898017B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
AT408416B (de) * 1996-07-19 2001-11-26 Norbert Fuchs Pharmazeutische bzw. diätetische zusammensetzungen
EP1350515A1 (en) * 2002-04-05 2003-10-08 Btg International Limited Low-dose potassium supplementation for the prevention and treatment of hypertension
WO2003086423A1 (en) * 2002-04-05 2003-10-23 Btg International Limited Low-dose potassium supplementation for the prevention and treatment of hypertension
US20040202726A1 (en) * 2003-04-10 2004-10-14 Deshay Samuel L. Topical blood pressure composition
US10251909B2 (en) * 2007-02-09 2019-04-09 Board Of Regents, The University Of Texas System Potassium-magnesium citrate as a surrogate of the DASH diet in managing hypertension
US20090022853A1 (en) * 2007-07-16 2009-01-22 Conopco, Inc., D/B/A Unilever Beverage
MX352695B (es) * 2008-02-06 2017-12-05 Campbell Soup Co Metodos y composiciones para reducir el contenido de sodio en productos alimenticios.
WO2010026136A1 (en) * 2008-09-05 2010-03-11 Unilever Nv Beverages comprising potassium
CN114272263A (zh) * 2022-01-10 2022-04-05 伍永田 一种用于治疗高血压疾病的水配方

Family Cites Families (13)

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US2611730A (en) * 1950-09-02 1952-09-23 Simth Kline & French Lab Medical preparation for reducing the body level of sodium
GB1195381A (en) * 1967-04-28 1970-06-17 Arthur H Cox & Company Ltd Pharmaceutical Compositions Comprising Potassium and Chlorine
US3639585A (en) * 1968-03-29 1972-02-01 Res Inst Medicine Chem Method of preventing corticosteroid-induced adverse effects on bon and compositions useful in said method
US3541208A (en) * 1968-09-10 1970-11-17 Arcom Holding Corp Relief of arthritis with a soluble silicate and a soluble polyphosphate
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SU858830A1 (ru) * 1974-10-23 1981-08-30 Институт медико-биологических проблем Средство дл лечени нарушений ритма сердца
SU946545A1 (ru) * 1978-05-04 1982-07-30 Институт Медико-Биологических Проблем Министерства Здравоохранения Ссср Способ восполнени калиевого дефицита в ткан х
FR2432869A1 (fr) * 1978-08-08 1980-03-07 Armour Montagu Laboratoire Compositions pour le traitement de l'osteoporose associant la calcitonine et le phosphore
US4405596A (en) * 1978-10-16 1983-09-20 Helbig Joachim W Pharmaceutical preparations for and treatment procedures involving increasing plasma bicarbonate level
US4289750A (en) * 1978-10-16 1981-09-15 Kopp Klaus F Therapy of conditions which may be associated with altered renal function and dosage forms therefor
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US4704269A (en) * 1985-06-11 1987-11-03 Hudson Pharmaceutical Corporation Effervescent antacid and analgesic compositions
JPH0619063B2 (ja) * 1986-04-09 1994-03-16 日本エステル株式会社 粉体塗料用樹脂組成物

Also Published As

Publication number Publication date
AU4515489A (en) 1990-05-14
ATE145825T1 (de) 1996-12-15
DE68927519T2 (de) 1997-04-03
JPH04501419A (ja) 1992-03-12
AU635231B2 (en) 1993-03-18
KR0178033B1 (ko) 1999-03-20
IL92075A0 (en) 1990-07-12
EP0720855A3 (en) 1998-07-08
DE68913311D1 (de) 1994-03-31
AU634988B2 (en) 1993-03-11
DE68927519D1 (de) 1997-01-16
EP0440738B1 (en) 1996-12-04
EP0461111A1 (en) 1991-12-18
HU208923B (en) 1994-02-28
DK72791A (da) 1991-05-14
IL92076A (en) 1995-08-31
CA2001123A1 (en) 1990-04-21
AU4622089A (en) 1990-05-14
DK72691A (da) 1991-04-22
DK175841B1 (da) 2005-03-29
JP2948247B2 (ja) 1999-09-13
CA2001124C (en) 2000-01-18
EP0440738A4 (en) 1991-08-28
EP0440738A1 (en) 1991-08-14
WO1990004403A1 (en) 1990-05-03
DE68913311T2 (de) 1994-05-26
IL92076A0 (en) 1990-07-12
US5804204A (en) 1998-09-08
EP0461111B1 (en) 1994-02-23
HUT63058A (en) 1993-07-28
KR0163583B1 (ko) 1998-12-01
HU212106B (en) 1996-02-28
DK72691D0 (da) 1991-04-19
ZA898017B (en) 1990-12-28
ZA898018B (en) 1990-12-28
KR900701287A (ko) 1990-12-01
DK72791D0 (da) 1991-04-19
HUT57989A (en) 1992-01-28
HU896567D0 (en) 1991-07-29
HU896889D0 (en) 1991-07-29
EP0720855A2 (en) 1996-07-10
IL92075A (en) 1995-07-31
JP2843146B2 (ja) 1999-01-06
JPH04501724A (ja) 1992-03-26
CA2001123C (en) 2000-01-18
CA2001124A1 (en) 1990-04-21
DK175840B1 (da) 2005-03-29
WO1990004402A1 (en) 1990-05-03
EP0461111A4 (en) 1991-07-25

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