KR900700090A - 항녹내장성 안과용 조성물 - Google Patents

항녹내장성 안과용 조성물

Info

Publication number
KR900700090A
KR900700090A KR1019890702432A KR890702432A KR900700090A KR 900700090 A KR900700090 A KR 900700090A KR 1019890702432 A KR1019890702432 A KR 1019890702432A KR 890702432 A KR890702432 A KR 890702432A KR 900700090 A KR900700090 A KR 900700090A
Authority
KR
South Korea
Prior art keywords
beta
intraocular pressure
ophthalmic composition
epinephrine
topical ophthalmic
Prior art date
Application number
KR1019890702432A
Other languages
English (en)
Other versions
KR0124465B1 (ko
Inventor
엠. 드샌티스 루이스
Original Assignee
존. 에프. 맥인티리
알콘 레보레이토리 인코오포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22684861&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR900700090(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 존. 에프. 맥인티리, 알콘 레보레이토리 인코오포레이티드 filed Critical 존. 에프. 맥인티리
Publication of KR900700090A publication Critical patent/KR900700090A/ko
Application granted granted Critical
Publication of KR0124465B1 publication Critical patent/KR0124465B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

항녹내장성 안과용 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 안구내 압력을 조절하는데 효과적인 베타-2 작용제 및 베타-1 선택성 베타블록커들의 혼합물 및 약제학적으로 허용될 수 있는 매체들로 구성되는 것을 특징으로 하는 안구내 압력 조절에 유용한 국소적 안과용 조성물.
  2. 제1항에 있어서, 상기 베타-2 작용제가 에피네프린, 노레피네프린, 이소프로테레놀 및 에피네프린과 노레페네프린의 피발로이록시 및 페닐아세티록시 에스테르에서 선택되고 베타-1 선택성 베타-블록커들이 아세부토롤, 아디모롤(adimolol), 아테노롤(atenolol), 베타소롤, 베푸노롤(befunolol), 비소프로롤(bisoprolol), 카테오롤(carteolol), 셀리프로롤(celiprolol), 세타모롤(cetamolol), 시클로프로롤(cicloprolol), 드라퀴노롤(draquinolol), 에파노롤(epanolol), 에스모롤(esmolol), 메토프로롤(metoprolol), SKF 95018, 살카르도롤(salcardolol), 티에노소롤(tienoxolol), 톨라모롤(tolamolol) 및 사모테롤(xamoterol)에서 선택되는 것을 특징으로 하는 안구내 압력 조절에 유용한 국소적 안과용 조성물.
  3. 제1항에서 있어서, 상기 베타-2 작용제가 에피네프린으로 구성되고 상기 베타-1 선택성 베타-블록커가 베타소롤로 구성되는 것을 특징으로 하는 안구내 압력 조절에 유용한 국소적 안과용 조성물.
  4. 제1항에 있어서, 상기 베타-2 작용제가 디파발릴에피네프린으로 제1항에 있어서, 상기 베타-2작용제가 에피네프린으로 구성되고 상기 베타-1 선택성 베타-블록커가 베타소롤로 구성되는 것을 특징으로 하는 안구내 압력 조절에 유용한 국소적 안과용 조성물.
  5. 제1항의 조성물을 치료법상으로 효과적인 양만큼 감염된 눈에 국소적으로 사용하여 안구내 압력을 조절하는 것을 특징으로 하는 안구내 압력 조절에 유용한 국소적 안과용 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890702432A 1988-04-26 1989-04-26 항녹내장성 안과용 조성물 KR0124465B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18641588A 1988-04-26 1988-04-26
US186,415 1988-04-26
PCT/US1989/001748 WO1989010120A1 (en) 1988-04-26 1989-04-26 Antiglaucoma compositions containing combinations of sympathomimetic agents and beta-1 selective beta-blockers

Publications (2)

Publication Number Publication Date
KR900700090A true KR900700090A (ko) 1990-08-11
KR0124465B1 KR0124465B1 (ko) 1997-11-25

Family

ID=22684861

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890702432A KR0124465B1 (ko) 1988-04-26 1989-04-26 항녹내장성 안과용 조성물

Country Status (9)

Country Link
EP (1) EP0366765B1 (ko)
JP (1) JPH02504150A (ko)
KR (1) KR0124465B1 (ko)
AT (1) ATE114461T1 (ko)
AU (1) AU617479B2 (ko)
CA (1) CA1338519C (ko)
DE (1) DE68919649T2 (ko)
DK (1) DK645489A (ko)
WO (1) WO1989010120A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201079C3 (de) * 1992-01-17 1997-09-11 Gramer Eugen Kombinationspräparate zur Augeninnendrucksenkung
EP0582321A1 (de) * 1992-01-17 1994-02-09 Gramer, Eugen, Prof.Dr.med.Dr.jur. Kombinationspräparat auf der Basis von Dipivalylepinephrin (DPE) und Betablocker zur Augeninnendrucksenkung
US6015837A (en) * 1996-08-29 2000-01-18 New York Medical College Method for treating scoliosis with β2-adrenoceptor agonists
EP1781331A1 (en) * 2004-08-09 2007-05-09 Université Catholique de Louvain Use of agonists and antagonists of beta-adrenoceptors for treating arterial diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852468A (en) * 1967-02-27 1974-12-03 Ici Ltd Alkanolamine derivatives as {62 -adrenergic blocking agents

Also Published As

Publication number Publication date
AU617479B2 (en) 1991-11-28
CA1338519C (en) 1996-08-13
WO1989010120A1 (en) 1989-11-02
DK645489D0 (da) 1989-12-19
EP0366765A4 (en) 1990-12-05
AU3555989A (en) 1989-11-24
EP0366765B1 (en) 1994-11-30
ATE114461T1 (de) 1994-12-15
DK645489A (da) 1989-12-19
EP0366765A1 (en) 1990-05-09
DE68919649T2 (de) 1995-04-06
JPH02504150A (ja) 1990-11-29
DE68919649D1 (de) 1995-01-12
KR0124465B1 (ko) 1997-11-25

Similar Documents

Publication Publication Date Title
ES2042625T3 (es) Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular.
PT639563E (pt) Utilizacao de ester de isopropilo de fluprostenol para a producao de um medicamento para o tratamento do glaucoma e hipertensao ocular
IE811654L (en) Ophthalmic composition
PT868186E (pt) Utilizacao de certos compostos de isoquinolinossulfonilo para tratamento de glaucoma e isquemia ocular
ES2062102T3 (es) Derivados de prostaglandinas para el tratamiento de glaucoma o hipertension ocular.
KR900700090A (ko) 항녹내장성 안과용 조성물
DE69430538D1 (de) 2-azylalkyl-oder arylalenyl-cyclopentanheptan-und heptensäuren, derivate und therapeutische anwendung
AU4610593A (en) Pharmaceutical composition
AU7913894A (en) Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
HK1009941A1 (en) Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
DE59303678D1 (de) Neue lederfettungsmittel und ihre verwendung
KR880001290A (ko) β-차단제 및 필로카르핀-함유 제제
PT1021184E (pt) Utilizacao de flunarizina para o tratamento topico da hipertensao ocular
PT92589A (pt) Processo para a preparacao de profarmacos de 3,4-hidroxi-benzoiloxipropanolaminas com accao beta-bloqueadora oculo-selectiva e de composicoes farmaceuticas que os contem
KR870002050A (ko) 안(眼) 선택성 β-차단제
Mehra et al. Pargyline drops in glaucoma
KR910011240A (ko) 눈의 약학적 제재 조성물 및 이를 이용한 치료방법
DE3688503T2 (de) Erhöhung des ausfliessens wässriger körperfluessigkeit.
KR950032113A (ko) 프로스타글란딘 에프 에스테르
JPS5639015A (en) Ophthalmic solution for regulating intraocular tension
Waltman Topical Fluorescein Penetration: Reply
KR940002359A (ko) 슈도모나스 에스 피. af-2001균을 이용한 항진균 물질의 제조방법
MX9202807A (es) Conposiciones y metodos para tratamiento de glaucoma por la administracion topica de t-butilamino-3(4-morfolin-1,2,5-tiadiazol-3-iloxi-2-propanol hidrogeno maleato.

Legal Events

Date Code Title Description
A201 Request for examination
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee