KR890701769A - 인체내 항원 및 또는 항체를 검출하기 위한 동시효소 면역 분석법 - Google Patents

인체내 항원 및 또는 항체를 검출하기 위한 동시효소 면역 분석법

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KR890701769A
KR890701769A KR1019890700262A KR890700262A KR890701769A KR 890701769 A KR890701769 A KR 890701769A KR 1019890700262 A KR1019890700262 A KR 1019890700262A KR 890700262 A KR890700262 A KR 890700262A KR 890701769 A KR890701769 A KR 890701769A
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antibody
test sample
antigen
immunoassay
binding pair
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KR1019890700262A
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에이치.코트라이트 케네쓰
이. 호프하인쯔 데이비드
마이클 올맨 데이비드
앤 포맨 메틸
송애리
엘리자베쓰 스마리가 폴레트
슈 스토너 캔디
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마이론 시.카스
쿠울터 코오포레이숀
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Abstract

내용 없음

Description

인체내 항원 및 또는 항체를 검출하기 위한 동시효소 면역 분석법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (14)

  1. (a) 단일 결합쌍 중의 다른 것을 함유하는 대응 항원 결정인자와 결합할 수 있는 항체가 결합되어 있는 고체 표면과 시험 시료를 접촉시키고, 정상적으로 음성인 시험 시료에 대하여 유용한 검출 가능한 시그널을 제공하도록 선택된 소정량의 항원을 도입하고 ; (b) 생성된 복합체를 보온하고 이것을 정상 시험 시료에 대한 시그널과 연관된 정량적으로 측정 가능한 시그널을 발생할 수 있는 접합 시그널 발생 조합으로 만들어 시험 시료가 항원 양성, 항체 양성 또는 상기 정상 음성인가를 지시하도록 함을 특징으로 하는 순환 항원을 가질 수 있는 인간 생리액 시험 시료중의 단일 결합쌍의 항원 및/또는 항체를 동시에 검출하기 위한 단일 면역분석법.
  2. 제1항에 있어서, 단계(a)의 시험 시료 및 소정량의 항원을 시험 시료중에 존재할 수 있는 항원을 균질하게 분배시키기 위한 용해 시약과 접촉시키는 단계를 포함하는 면역 분석법.
  3. 제1항에 있어서, 단일 결합쌍의 항원 및/또는 항체가 각각 HIV 항원 또는 항-HIV 항체를 함유하는 면역분석법.
  4. 제1항에 있어서, 대응 항원 결정 인자와 결합할 수 있는 단계(a)의 항체가 인간 및 염소를 포함한 포유 동물군에서 유래되는 면역 분석법.
  5. 제1항에 있어서, 단계(b)가 ELISA 방법에 의해 실시되는 면역분석법.
  6. (a) 단일 결합쌍의 항체가 결합되어 있는 고체 표면과 시험 시료를 접촉시키고, 정상적으로 음성인 시험시료에 대해 유용한 검출 가능한 비색 시그널을 제공하도록 선택된 소정량의 단일 결합쌍의 항원, 및 시험 시료중에 존재할 수 있는 항원을 방출시키기 위한 용해 시약을 도입하고 ; (b) 생성된 복합체를 보온하고, 이것을 보온 후에 정상 시험 시료에 대한 검출 가능한 시그널과 관련된 색 검출 시그널을 유발하는 적절한 기질 및 당단백질 결합 항체 접합체로 만들어 시험 시료가 항원 양성, 항체 양성 또는 상기 정상 음성인가를 지시하도록 함을 특징으로 하는 시험 시료중의 단일 결합쌍의 항원 및/또는 항체를 검출하는 단일 효소-결합면역 흡착 분석법.
  7. 제6항에 있어서, 단일 결합쌍의 항원 및/또는 항체가 각각 HIV 항원 또는 항-HIV 항체를 함유하는 면역 분석법.
  8. 제6항에 있어서, 대응 항원결정인자와 결합할 수 있는 단계(a)의 항체가 인간 및 염소를 포함한 포유 동물군에서 유래되는 면역 분석법.
  9. 제6항에 있어서, 단계(b)가 ELISA 방법에 의해 실시되는 면역분석법.
  10. 시험 시료중의 단일 결합쌍의 항원 및/또는 항체를 분광측광에 의해 검출하기 위한 효소-결합 면역 흡착 분석법에 있어서, 비오티닐화 항체의 존재하에 시험 시료를 보온하기 전에 정상적으로 음성인 시험 시료에 대해 유용한 검출 가능한 비색 시그널을 제공하도록 선택된 소정량의 상기 항체를 시험 시료에 도입하여 분석 완결시에 검출 가능한 색 시그널이 제공되도록 함을 특징으로 하는 개량 방법.
  11. 제10항에 있어서, 단일 결합쌍의 항원 및/또는 항체가 각각 HIV 항원 또는 항-HIV 항체를 함유하는 면역분석법.
  12. 제10항에 있어서, 대응 항원 결정인자와 결합할 수 있는 단계(a)의 항체가 인간 및 염소를 포함한 포유 동물군에서 유래되는 면역 분석법.
  13. 제10항에 있어서, 단계(b)가 ELISA 방법에 의해 행해지는 면역분석법.
  14. (a) 단일 결합쌍의 다른 것을 함유하는 대응 항원 결정인자와 결합할 수 있는 항체가 결합된 고체 표면 ; (b) 정상적으로 음성인 시험 시료에 대한 유용한 검출가능한 시그널을 제공하는 단일 결합쌍의 다른 것을 함유하는 공지된 농도의 양의 항원 ; (c) 시험 시료에 존재할 수 있는 결합쌍의 항원을 균질하게 분배시키기 위한 양의 용해제 ; 및 (d) 면역분석을 수행하는데 있어서 키트를 사용한 결과 생성되는 면역 반응을 가시화 하는데 필요한 물질을 조합하여 함유함을 특징으로 하는 제1항에 따른 면역 분석법을 실시하는데 사용하기 위한 키트.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890700262A 1987-06-15 1988-03-14 인체내 항원 및 또는 항체를 검출하기 위한 동시효소 면역 분석법 KR890701769A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/061,979 US4870003A (en) 1987-06-15 1987-06-15 Simultaneous enzyme immunoassay for detecting antigen and/or antibody in humans
US07/061,979 1987-06-15
PCT/US1988/000877 WO1988010316A1 (en) 1987-06-15 1988-03-14 Simultaneous enzyme immunoassay for detecting antigen and/or antibody in humans

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KR890701769A true KR890701769A (ko) 1989-12-21

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US (1) US4870003A (ko)
EP (1) EP0366654A4 (ko)
JP (1) JPH02503950A (ko)
KR (1) KR890701769A (ko)
CN (1) CN1030300A (ko)
BR (1) BR8807567A (ko)
CA (1) CA1303494C (ko)
ES (1) ES2009939A6 (ko)
IL (1) IL86677A0 (ko)
WO (1) WO1988010316A1 (ko)
ZA (1) ZA882998B (ko)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5108891A (en) * 1988-06-09 1992-04-28 Beth Israel Medical Center Aids assay
AU7160491A (en) * 1989-11-29 1991-06-26 Baxter Diagnostics Inc. Methods of coating viral antigens in the presence of nonionic detergents and acidic ph onto a solid phase
CA2133826A1 (en) * 1992-04-09 1993-10-28 James L. Gallarda Assay for detection of hiv antigen and hiv antibody
US5391479A (en) * 1992-10-29 1995-02-21 E. I. Du Pont De Nemours And Company Method for determining total analyte concentration in a sample having both free and bound analyte
FR2703788B1 (fr) * 1993-04-09 1996-12-20 Jacques Toledano Dispositif et procede anti-idiotype de detection immunologique.
US5641624A (en) * 1994-06-02 1997-06-24 Sloan-Kettering Institute For Cancer Research Method for measuring anti-HIV-1 p24 antibody and use thereof
JPH11508036A (ja) * 1995-06-07 1999-07-13 アボツト・ラボラトリーズ 抗−ｈｉｖ−１または抗−ｈｉｖ−２抗体を検出するための改良されたハプテン−ペプチド結合物
US6383740B2 (en) * 1999-07-30 2002-05-07 Bioergonomics, Inc. Methods for simultaneously detecting both members of a binding pair
FR2839555B1 (fr) * 2002-05-10 2007-07-27 Bio Rad Pasteur Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux
EP3527976A1 (en) * 2004-07-19 2019-08-21 ProteinSimple Method and device for analyte detection
US7935479B2 (en) 2004-07-19 2011-05-03 Cell Biosciences, Inc. Methods and devices for analyte detection
US20060292558A1 (en) * 2004-07-19 2006-12-28 Cell Biosciences Inc. Methods and apparatus for protein assay diagnostics
US7846676B2 (en) * 2004-07-19 2010-12-07 Cell Biosciences, Inc. Methods and devices for analyte detection
US7387890B2 (en) * 2004-12-16 2008-06-17 Chembio Diagnostic Systems, Inc. Immunoassay devices and use thereof
CN101088014B (zh) * 2004-12-23 2012-10-03 弗·哈夫曼-拉罗切有限公司 在实验动物中检测治疗性抗体
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
WO2007035864A2 (en) 2005-09-20 2007-03-29 Cell Biosciences, Inc. Electrophoresis standards, methods and kits
CN100397083C (zh) * 2005-11-03 2008-06-25 北京望尔生物技术有限公司 检测呋喃唑酮代谢物的酶联免疫试剂盒及方法
CN100403030C (zh) * 2006-05-10 2008-07-16 北京望尔生物技术有限公司 检测苏丹红药物的酶联免疫试剂盒及方法
US20080017512A1 (en) * 2006-07-24 2008-01-24 Bordunov Andrei V Coatings for capillaries capable of capturing analytes
US20100022916A1 (en) 2008-07-24 2010-01-28 Javanbakhsh Esfandiari Method and Apparatus for Collecting and Preparing Biological Samples for Testing
US20100297607A1 (en) * 2009-05-20 2010-11-25 Jian Zheng Reagents For HCV Antigen-Antibody Combination Assays
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
RS57397B8 (sr) 2011-06-10 2020-01-31 Univ Oregon Health & Science Cmv glikoproteini i rekombinantni vektori
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
US9804079B2 (en) 2012-04-19 2017-10-31 ProteinSimple Dual wavelength isoelectric focusing for determining drug load in antibody drug conjugates
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
KR102459433B1 (ko) 2013-03-11 2022-10-25 메소 스케일 테크놀러지즈, 엘엘시 다중화 어세이를 수행하기 위한 올리고뉴클레오티드
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
US9766206B2 (en) 2013-09-27 2017-09-19 ProteinSimple Apparatus, systems, and methods for capillary electrophoresis
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
ES2906853T3 (es) 2014-04-02 2022-04-20 Chembio Diagnostic Systems Inc Inmunoensayo que utiliza conjugado de atrapamiento
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
CA2971389C (en) * 2014-12-19 2020-10-06 Siemens Healthcare Diagnostics Inc. Methods and systems for improving precision of measurements for reduced sample volumes
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9925258B2 (en) 2015-10-02 2018-03-27 International Aids Vaccine Initiative Replication-competent VSV-HIV Env vaccines
CN106018805B (zh) * 2016-07-15 2017-11-14 中南大学湘雅三医院 一种非诊断目的的hiv抗体免疫检测方法及试剂盒
CN106771218B (zh) * 2016-12-06 2019-03-22 河北医科大学生物医学工程中心 一种检测HIV-1 p24抗原的试剂盒及其应用
CN111272997A (zh) * 2017-11-27 2020-06-12 科美诊断技术股份有限公司 一种均相免疫检测试剂盒、检测方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172117A (en) * 1974-05-20 1979-10-23 Biotest-Serum-Institut Gmbh Method for the simultaneous measurement of antigens and their antibodies by solid-phase radioimmunoassay
US4661445A (en) * 1985-05-24 1987-04-28 Saxinger W Carl Competitive ELISA for the detection of HTLV-III antibodies
US4748110A (en) * 1985-09-25 1988-05-31 Abbott Laboratories Immunoassay for HTLV-III antigens

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