KR890006810A - 스트레팍스 및 이를 생성 하는 균주 - Google Patents

스트레팍스 및 이를 생성 하는 균주 Download PDF

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Publication number
KR890006810A
KR890006810A KR870011693A KR870011693A KR890006810A KR 890006810 A KR890006810 A KR 890006810A KR 870011693 A KR870011693 A KR 870011693A KR 870011693 A KR870011693 A KR 870011693A KR 890006810 A KR890006810 A KR 890006810A
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South Korea
Prior art keywords
strepax
streptococcus
amino acids
strain
bile
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KR870011693A
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English (en)
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KR900003303B1 (ko
Inventor
강박운
김대운
Original Assignee
허영섭
주식회사 녹십자
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Priority to KR1019870011693A priority Critical patent/KR900003303B1/ko
Publication of KR890006810A publication Critical patent/KR890006810A/ko
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Publication of KR900003303B1 publication Critical patent/KR900003303B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor

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  • Biomedical Technology (AREA)
  • Virology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

스트레팍스 및 이를 생성 하는 균주
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 스트레팍스 중에 함유된 아미노산의 분석 크로마토그램.
제2도는 스트레팍스의 적외선 흡수 스펙트럼.
제3도는 스트레팍스의 NMR스펙트럼.
제4도는 스트레팍스가 동물 백혈구에 미치는 영향.

Claims (5)

  1. 다음과 같은 물리화학적 특성을 갖는 스트레팍스:
    (1)평균 분자량: 약71.700±500
    (2)성상 및 용해도:담황색 분말로서 물에 용이하게 녹으며, 메탄올, 에탄올, 아세톤, 에테르 등에는 불용
    (3)다당체 함량:
    당함량(%):90.8±1.2(페놀-황산법에 의함; 표준물질:만노오즈)
    단백질 함량(%):9.2±1.2(로우리-폴린법에 의함; 표준물질:소혈청 알부민
    (4)안정 pH:pH3.0-6.2(최적 pH 5.0)
    (5)아미노산 및 아미노산의 조성:아미노산 분석기로 분석한 결과, 구성 아미노산의 17종 이었으며, 주로 아스파르트산, 글루타민산, 세린, 글리신 및 트레오닌이 존재함을 알았음
    (6)적외선 흡수 스펙트럼에서 특색적인 흡수밴드:
    3450㎝-1,1150-1000cm-1,810cm-1(KBr)
    (7)NMR(1H)스펙트럼:제3도와 같음
  2. 유효 성분으로서 스트레팍스로 이루어진 면역증강제
  3. 제2항에 있어서, 면역증강제가 악성종양, 양성종양, 암에 효과적임을 특징으로 하는 면역증강제.
  4. 스트레팍스를 생성 하는 후술의 세균학적 특성을 나타냄을 특징으로 하는 프트렙토코카스:
    1)그램균주:양성
    2)평판 배지에서의 성장:
    ⅰ)혈액 아가...α-용혈현상
    ⅱ)맥콘게이 아가...성장 없음
    ⅲ)T.C.B.S.아가...작은 원형의 황색군락
    3)생리적 특성(+:양성, -:음성)
    옥시다제
    카탈라제 -
    6.5% NaCl +
    10% 담즙 +
    40% 담즙 +
    고유운동성 -
    시트르산염 -
    알기닌 가수분해+
    글루코오즈 +
    락토오즈 +
    슈크로오즈 +
    만니톨 +
    살리신 +
    소르비톨 -
    라피노오즈 +
    아라비노오즈 +
    OF시험 변화없음
  5. 제4항에 있어서, 스트렙토코카스 균주가 스트렙토코카스 패시움 G-1001(한국 종균협회 기탁번호 KFCC-10447)인 것이 특징인 균주.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870011693A 1987-10-21 1987-10-21 스트레팍스 및 이를 생성하는 균주 KR900003303B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019870011693A KR900003303B1 (ko) 1987-10-21 1987-10-21 스트레팍스 및 이를 생성하는 균주

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019870011693A KR900003303B1 (ko) 1987-10-21 1987-10-21 스트레팍스 및 이를 생성하는 균주

Publications (2)

Publication Number Publication Date
KR890006810A true KR890006810A (ko) 1989-06-16
KR900003303B1 KR900003303B1 (ko) 1990-05-14

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KR1019870011693A KR900003303B1 (ko) 1987-10-21 1987-10-21 스트레팍스 및 이를 생성하는 균주

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KR900003303B1 (ko) 1990-05-14

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