KR890004673A - Glass microbeads having bactericidal properties and a method for producing the same. - Google Patents

Glass microbeads having bactericidal properties and a method for producing the same. Download PDF

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Publication number
KR890004673A
KR890004673A KR1019880011564A KR880011564A KR890004673A KR 890004673 A KR890004673 A KR 890004673A KR 1019880011564 A KR1019880011564 A KR 1019880011564A KR 880011564 A KR880011564 A KR 880011564A KR 890004673 A KR890004673 A KR 890004673A
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KR
South Korea
Prior art keywords
microbead
protein
beads
glass
microbeads
Prior art date
Application number
KR1019880011564A
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Korean (ko)
Inventor
델장 마르셀
Original Assignee
엘 띠뜨 가-반덴베르겐, 제이 드 케르스 매케르
글라베르벨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 엘 띠뜨 가-반덴베르겐, 제이 드 케르스 매케르, 글라베르벨 filed Critical 엘 띠뜨 가-반덴베르겐, 제이 드 케르스 매케르
Publication of KR890004673A publication Critical patent/KR890004673A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
    • C03C17/28—Surface treatment of glass, not in the form of fibres or filaments, by coating with organic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G7/00—Beds specially adapted for nursing; Devices for lifting patients or disabled persons
    • A61G7/05—Parts, details or accessories of beds
    • A61G7/057—Arrangements for preventing bed-sores or for supporting patients with burns, e.g. mattresses specially adapted therefor
    • A61G7/05738—Arrangements for preventing bed-sores or for supporting patients with burns, e.g. mattresses specially adapted therefor with fluid-like particles, e.g. sand, mud, seeds, gel, beads
    • A61G7/05746—Arrangements for preventing bed-sores or for supporting patients with burns, e.g. mattresses specially adapted therefor with fluid-like particles, e.g. sand, mud, seeds, gel, beads fluidised by air flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nursing (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Materials Engineering (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Surface Treatment Of Glass (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Invalid Beds And Related Equipment (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Glass Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

내용 없음No content

Description

제균 성질을 갖는 유리 마이크로 비이드 및 그 제조방법Glass microbeads with bactericidal properties and preparation method thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (20)

유리에 공유적으로 결합되어 비이드에 제균 성질을 부여하는 단백질로 비이드가 피복되는 것을 특징으로 하는 유리 마이크로 비이드(microbeads).Glass microbeads, characterized in that the beads are coated with proteins covalently bound to the glass to impart antibacterial properties to the beads. 제1항에 있어서, 상기 마이크로 비이드가 비 다공성 표면을 갖는 마이크로 비이드.The microbead of claim 1, wherein the microbead has a nonporous surface. 제1항 또는 제2항에 있어서, 피복물이 효소를 포함하는 유리 마이크로 비이드.The glass microbead of claim 1, wherein the coating comprises an enzyme. 제1항 또는 제2항에 있어서, 상기 단백질이 락토폐린 및 락토페록시다제로부터 선택된 마이크로 비이드.The microbead of claim 1 or 2, wherein said protein is selected from lactoferrin and lactoperoxidase. 제1항 내지 제4항중 어느 한 항에 있어서, 상기 단백질이 0.1 중량% 보다 작은, 바람직하게는 0.05중량% 보다 작은 비유로 존재하는 마이크로 비이드.5. The microbead of claim 1, wherein said protein is present in an analogue of less than 0.1% by weight, preferably less than 0.05% by weight. 6. 제1항 내지 제5항에 있어서, 상기 단백질이 실란-형결합체를 통해 유리에 결합되는 마이크로 비이드.The microbead of claim 1, wherein said protein is bound to the glass through a silane-like conjugate. 제6항에 있어서, 상기 단백질이 실란 및 두번째 결합제를 통해 유리에 결합되는 마이크로 비이드.7. The microbead of claim 6 wherein said protein is bound to the glass through a silane and a second binder. 제7항에 있어서, 두번째 결합제가 글루타트알데히드인 마이크로 비이드.8. The microbead of claim 7, wherein the second binder is glutathaldehyde. 제1항 내지 제8항중 어느 한 항에 있어서, 소수성인 마이크로 비이드.The microbead according to any one of claims 1 to 8, which is hydrophobic. 제9항에 있어서, 실리콘 피복물을 함유하는 마이크로 비이드.10. The microbead of claim 9 containing a silicone coating. 제1항 내지 10항중 어느 한 항에 있어서, 평균 지름이 80-100μm, 바람직하게는 85-90μm인 마이크로 비이드.The microbead according to claim 1, wherein the average diameter is 80-100 μm, preferably 85-90 μm. 제1항 내지 제11항중 어느 한 항에 있어서, 유동화 기체안에 현탁되어 있는 마이크로 비이드.The microbead according to any one of claims 1 to 11, which is suspended in a fluidizing gas. 제12항에 따른 마이크로 비이드를 함유하는 것을 특징으로 하는, 유동화 시스템을 포함하는, 화상 환자의 치료를 위한 베드.A bed for the treatment of burn patients, comprising a fluidization system, characterized in that it contains a microbead according to claim 12. 단백질 피복물을 유리 마이크로 비이드에 공유적으로 결합시키는 것을 특징으로 하는, 유리 마이크로 비이드에 제균 성질을 부여하는 방법.A method of imparting bactericidal properties to glass microbeads, characterized in that the protein coating is covalently bound to the glass microbeads. 제14항에 있어서, 단백지를 함유하는 배지와 접촉시키기 전에 상기 비이드를 실란형 결합제로 처리하는 방법.15. The method of claim 14, wherein said beads are treated with a silane type binder prior to contacting with a medium containing protein paper. 제15항에 있어서, 실란 처리에 뒤이어서 비이드상에 두번째 결합제를 부착시키는 방법.The method of claim 15, wherein the second binder is attached onto the beads following silane treatment. 제14항 내지 제16항중 어느 한 항에 있어서, pH가 7이하인 상기 단백질을 함유하는 배지와 비이드를 접촉시킴으로써 상기 단백질을 비이드에 결합시키는 방법.The method of claim 14, wherein the protein is bound to the beads by contacting the beads with a medium containing the protein having a pH of 7 or less. 제14항 내지 제17항중 어느 한 항에 있어서, 상기 단백질을 비이드에 결합시킨 후에, 이들을 실리콘을 함유하는 용액과 접촉시키는 방법.18. The method of any one of claims 14-17, wherein after binding the protein to the beads, they are contacted with a solution containing silicon. 제18항에 있어서, 단백질로 피복시키기전에 열처리에 의해 비이드를 살륜시키는 방법.19. The method of claim 18, wherein the beads are fleshed by heat treatment prior to coating with the protein. 제19항에 따른 방법에 의해 처리된 실리콘 처리된 마이크로 비이드가 그 후 제14항 내지 17항중 어느 한 항에 따른 방법에 의해 처리되는, 사용된 유리 마이크로 비이드의 제균 성질을 회복시키는 방법.A method for restoring the disinfecting properties of the glass microbeads used, wherein the siliconized microbeads treated by the method according to claim 19 are then treated by the method according to any one of claims 14 to 17. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019880011564A 1987-09-07 1988-09-06 Glass microbeads having bactericidal properties and a method for producing the same. KR890004673A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU86987 1987-09-07
LU86987A LU86987A1 (en) 1987-09-07 1987-09-07 GLASS MICROBALLS WITH BACTERIOSTATIC PROPERTIES, METHOD FOR MANUFACTURING SUCH MICROBALLS

Publications (1)

Publication Number Publication Date
KR890004673A true KR890004673A (en) 1989-05-09

Family

ID=19730965

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880011564A KR890004673A (en) 1987-09-07 1988-09-06 Glass microbeads having bactericidal properties and a method for producing the same.

Country Status (16)

Country Link
JP (1) JP2542243B2 (en)
KR (1) KR890004673A (en)
AU (1) AU611936B2 (en)
BE (1) BE1000875A3 (en)
CA (1) CA1326209C (en)
DE (1) DE3830123A1 (en)
DK (1) DK498088A (en)
ES (1) ES2008620A6 (en)
FI (1) FI95458C (en)
FR (1) FR2619990B1 (en)
GB (1) GB2209523B (en)
IT (1) IT1223794B (en)
LU (1) LU86987A1 (en)
NL (1) NL8802169A (en)
NO (1) NO175854C (en)
SE (1) SE503238C2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU623968B2 (en) * 1989-01-19 1992-05-28 Fujitsu Limited Earth detecting circuit
US6592814B2 (en) * 1998-10-02 2003-07-15 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
FR2825373B1 (en) * 2001-05-31 2004-04-30 Tmi Europ PROCESS FOR THE ENZYMATIC PRODUCTION OF A FLUID TREATMENT AGENT
JP2009526862A (en) * 2006-02-15 2009-07-23 マサチューセッツ・インスティテュート・オブ・テクノロジー Medical devices and coatings containing non-exudable antimicrobial peptides
GB0616580D0 (en) * 2006-08-21 2006-09-27 Novathera Ltd Composite material
CA2888241C (en) 2012-10-16 2020-12-29 Surmodics, Inc. Wound packing device and methods
CN103251573B (en) * 2013-05-13 2014-10-29 李伟 Protein micro/nano sphere carrying antitumor chemotherapeutic medicine and preparation method of protein micro/nano sphere
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH545102A (en) * 1972-01-20 1973-12-15 Detec Sa Bed for the treatment of severe burns
US4478946A (en) * 1981-07-02 1984-10-23 South African Inventions Development Corporation Carrier bound immunosorbent
FR2523841B1 (en) * 1982-03-25 1985-10-25 Lacoste Francois FLUIDIZED BED FOR THERAPEUTIC USE
US4683203A (en) * 1984-04-14 1987-07-28 Redco N.V. Immobilized enzymes, processes for preparing same, and use thereof
JPS63146791A (en) * 1986-12-08 1988-06-18 Hitachi Ltd Immobilization of enzyme and immobilized enzyme

Also Published As

Publication number Publication date
GB8820574D0 (en) 1988-09-28
NO883945D0 (en) 1988-09-05
FI884091A (en) 1989-03-08
IT8867785A0 (en) 1988-09-02
LU86987A1 (en) 1989-04-06
NO175854C (en) 1994-12-21
CA1326209C (en) 1994-01-18
AU2171788A (en) 1989-03-09
FI95458B (en) 1995-10-31
JPH0193444A (en) 1989-04-12
BE1000875A3 (en) 1989-05-02
GB2209523B (en) 1991-08-21
NO883945L (en) 1989-03-08
FR2619990A1 (en) 1989-03-10
SE8803124D0 (en) 1988-09-06
DE3830123A1 (en) 1989-03-16
IT1223794B (en) 1990-09-29
FR2619990B1 (en) 1990-09-21
DK498088A (en) 1989-03-08
JP2542243B2 (en) 1996-10-09
ES2008620A6 (en) 1989-07-16
SE8803124L (en) 1989-03-08
NO175854B (en) 1994-09-12
FI95458C (en) 1996-02-12
DK498088D0 (en) 1988-09-07
AU611936B2 (en) 1991-06-27
GB2209523A (en) 1989-05-17
SE503238C2 (en) 1996-04-22
NL8802169A (en) 1989-04-03
FI884091A0 (en) 1988-09-06

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