KR880009026A - Rifamycin Derivative Salts - Google Patents

Rifamycin Derivative Salts Download PDF

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Publication number
KR880009026A
KR880009026A KR1019880000536A KR880000536A KR880009026A KR 880009026 A KR880009026 A KR 880009026A KR 1019880000536 A KR1019880000536 A KR 1019880000536A KR 880000536 A KR880000536 A KR 880000536A KR 880009026 A KR880009026 A KR 880009026A
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KR
South Korea
Prior art keywords
base
inorganic base
organic base
organic
rifamycin derivative
Prior art date
Application number
KR1019880000536A
Other languages
Korean (ko)
Other versions
KR960006393B1 (en
Inventor
브루제스 티베리오
세드로 아만도
한스 반 덴 호이벨 홀저
Original Assignee
알폰소 지암브로코노
스파 소시에타 프로도티 안티비오티시 에스.피.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알폰소 지암브로코노, 스파 소시에타 프로도티 안티비오티시 에스.피.에이. filed Critical 알폰소 지암브로코노
Publication of KR880009026A publication Critical patent/KR880009026A/en
Application granted granted Critical
Publication of KR960006393B1 publication Critical patent/KR960006393B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems

Abstract

내용 없음.No content.

Description

리파마이신 유도체 염Rifamycin Derivative Salts

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (4)

3-[(1-디에틸아미노에틸리덴)아지노메틸]리파마이신 SV를 수성 또는 유기 용매내 임의로 아스코르빈산 또는 그것의 염 존재에서 동몰 양의 적당한 무기 염기 또는 유기 염기와 반응시키고 얻은 염을 증발건조에 의해 또는 침전제에 의해 분리하는 것으로 구성되는, 다음 구조식 화합물의 제조방법.The salt obtained by reacting 3-[(1-diethylaminoethylidene) azinomethyl] rifamycin SV with an equimolar amount of an appropriate inorganic base or organic base, optionally in the presence of ascorbic acid or a salt thereof in an aqueous or organic solvent, A process for preparing a compound of formula [식중, B는 약리학적으로 허용가능한 비독성 무기 염기 또는 유기 염기.[Wherein B is a pharmacologically acceptable non-toxic inorganic base or organic base. 제1항에 있어서, 무기 염기가 수산화나트륨 또는 소듐 메톡사이드인 방법.The method of claim 1 wherein the inorganic base is sodium hydroxide or sodium methoxide. 제1항에 있어서, 유기 염기가 라이신인 방법.The method of claim 1 wherein the organic base is lysine. 사람의 경구, 비경구 또는 국소용 제약학적 제제를 제조하거나 전염병을 치료하는 수의학에 다음 구조식 화합물을 사용하는 방법.Use of the following structural compounds in the manufacture of oral, parenteral or topical pharmaceutical preparations in humans or in veterinary medicine to treat infectious diseases. [식중, B는 유기 염기 또는 무기 염기.][Wherein B is an organic base or an inorganic base.] ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019880000536A 1987-01-26 1988-01-25 Rifamycin derivative salts KR960006393B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19162A/87 1987-01-26
IT19162/87A IT1202424B (en) 1987-01-26 1987-01-26 SALTS OF A RIFAMICINIC DERIVATIVE

Publications (2)

Publication Number Publication Date
KR880009026A true KR880009026A (en) 1988-09-13
KR960006393B1 KR960006393B1 (en) 1996-05-15

Family

ID=11155406

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880000536A KR960006393B1 (en) 1987-01-26 1988-01-25 Rifamycin derivative salts

Country Status (7)

Country Link
KR (1) KR960006393B1 (en)
CN (1) CN1015368B (en)
ES (1) ES2006280A6 (en)
GB (1) GB2200353B (en)
IN (1) IN165924B (en)
IT (1) IT1202424B (en)
PT (1) PT86621B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0447813A1 (en) * 1990-02-28 1991-09-25 GRUPPO LEPETIT S.p.A. Water soluble salts of purpuromycin and pharmaceutical formulations thereof
BG64021B1 (en) * 1998-11-04 2003-10-31 КОНСТАНТИНОВА Румяна Sodium salt of 3-(4-cinnamyl-1-piperazinyl)-iminomethyl rifamycin and method for its preparation
UA120030C2 (en) * 2012-08-13 2019-09-25 Адіфарм Еад Pharmaceutical formulations containing 3-(4-cinnamyl-l-piperazinyl) amino derivatives of 3-formylrifamycin sv and 3-formylrifamycin s and a process of their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1201963B (en) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa DERIVATIVES OF THE REFAMICINE AND PROCEDURE FOR THEIR PREPARATION

Also Published As

Publication number Publication date
GB8801577D0 (en) 1988-02-24
IT8719162A0 (en) 1987-01-26
PT86621A (en) 1988-02-01
IN165924B (en) 1990-02-10
GB2200353B (en) 1990-11-28
PT86621B (en) 1991-12-31
GB2200353A (en) 1988-08-03
IT1202424B (en) 1989-02-09
CN88100328A (en) 1988-09-28
ES2006280A6 (en) 1989-04-16
KR960006393B1 (en) 1996-05-15
CN1015368B (en) 1992-02-05

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