KR880007487A - 피리미디닐 오가노포스페이트를 제조하는 방법 - Google Patents
피리미디닐 오가노포스페이트를 제조하는 방법 Download PDFInfo
- Publication number
- KR880007487A KR880007487A KR870014597A KR870014597A KR880007487A KR 880007487 A KR880007487 A KR 880007487A KR 870014597 A KR870014597 A KR 870014597A KR 870014597 A KR870014597 A KR 870014597A KR 880007487 A KR880007487 A KR 880007487A
- Authority
- KR
- South Korea
- Prior art keywords
- carbon atoms
- alkyl
- alkylthio
- hydrogen
- pyrimidinate
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 8
- 125000000714 pyrimidinyl group Chemical group 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 11
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- ZFCHNZDUMIOWFV-UHFFFAOYSA-N pyrimidine-2-carboxylic acid Chemical compound OC(=O)C1=NC=CC=N1 ZFCHNZDUMIOWFV-UHFFFAOYSA-N 0.000 claims 3
- 229910052717 sulfur Chemical group 0.000 claims 3
- 239000011593 sulfur Chemical group 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 239000003444 phase transfer catalyst Substances 0.000 claims 2
- -1 pyrimidinyl organophosphorus compound Chemical class 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 1
- 150000001342 alkaline earth metals Chemical class 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims 1
- 125000003253 isopropoxy group Chemical group [H]C([H])([H])C([H])(O*)C([H])([H])[H] 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 150000003242 quaternary ammonium salts Chemical group 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 다음 일반식(II)의 피리미디네이트를 함유하는 수용액을 상 전이촉매의 존재하 및 첨가된 유기용매의 부재하에서 다음 일반식(III)의 포스포로에스테르와 접촉반응시킴을 특징으로 하여 다음 일반식(I)의 피리미디닐 오가노포스포러스 화합물을 제조하는 방법.상기식에서, R은 탄소수 1 내지 6의 알킬이고; R1은 탄소수 1 내지 6의 알킬, 탄소수 1 내지 6의 알콕시, 탄소수 1 내지 6의 알킬티오 또는 모노알킬아미노 이며; R2는 수소, 탄소수 1 내지 8의 알킬, 탄소수 1 내지 4의 알케닐, 알킬의 탄소수가 1 내지 4인 알킬티오메틸, 알킬설피닐메틸 또는 알킬설포닐메틸, 페닐, 페닐티오, 알킬의 탄소수가 1 내지 4인 알킬티오, 알킬설피닐 또는 알킬설포닐, 또는 알킬의 탄소수가 l 내지 2인 알킬티오 에틸티오이고; R3은 수소, 또는 탄소수 1 내지 3의 알킬이며; R4는 수소, 탄소수 1 내지 4의 알킬, 또는 탄소수 1 내지 2의 알킬티오이고; X는 산소 또는 황이며; M+는 알칼리 금속, 알칼리 토금속 또는 암모늄 이고; Z는 할로겐, 바람직하게는 염소, 또는 토실레이트이다.
- 제1항에 있어서, R2가 3급-부틸이고, R3및 R4가 수소인 방법.
- 제1항에 있어서, M+이 나트륨 또는 칼륨인 방법.
- 제1항 내지 제3항 중의 어느 한 항에 있어서, Z가 할로겐이고, X가 황이며, R이 에틸이고, R1이 에톡시인 방법.
- 제1항 내지 제3항 중의 어느 한 항에 있어서, Z가 할로겐이고, X가 황이며, R이 에틸이고, R1이 이소프로폭시인 방법.
- 제1항 내지 제3항 중의 어느 한 항에 있어서, 상 전이촉매가 4급 암모늄염인 방법.
- 제1항 내지 제3항 중의 어느 한 항에 있어서, 수용액중의 피리미디네이트 농도가 5 내지 60중량% 범위인 방법.
- 제7항에 있어서, 피리미디네이트 농도가 15 내지 30중량%인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94525886A | 1986-12-22 | 1986-12-22 | |
| US945258 | 1986-12-22 | ||
| US945,258 | 1986-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR880007487A true KR880007487A (ko) | 1988-08-27 |
| KR900003395B1 KR900003395B1 (ko) | 1990-05-18 |
Family
ID=25482858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019870014597A KR900003395B1 (ko) | 1986-12-22 | 1987-12-21 | 피리미디닐 오가노포스페이트를 제조하는 방법 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0277292B1 (ko) |
| JP (1) | JPS63166896A (ko) |
| KR (1) | KR900003395B1 (ko) |
| AU (1) | AU603843B2 (ko) |
| BR (1) | BR8707053A (ko) |
| CA (1) | CA1310643C (ko) |
| DE (1) | DE3769969D1 (ko) |
| DK (1) | DK168442B1 (ko) |
| ES (1) | ES2038981T3 (ko) |
| HU (1) | HU202875B (ko) |
| IL (1) | IL84507A0 (ko) |
| NZ (1) | NZ222896A (ko) |
| RU (1) | RU1801112C (ko) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100775914B1 (ko) * | 2005-09-06 | 2007-11-15 | 중앙대학교 산학협력단 | 커패시터 및 그 제조방법 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5502190A (en) * | 1993-11-12 | 1996-03-26 | Bayer Corporation | Process for the production of dialkyl pyrimidylphosphates |
| ES2170609B1 (es) * | 1999-08-23 | 2003-12-16 | Aldecoa Juan Cruz Sarriugarte | Mecanismo de disparo para escopetas de cañones paralelos. |
| CA3137688A1 (en) * | 2019-05-28 | 2020-12-03 | Bromine Compounds Ltd. | Quaternary ammonium halides for treating halogen contamination |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6809749A (en) * | 1968-07-10 | 1970-01-13 | Di:alkyl aryl phosphoro:thioate prodn. - from phenol and phosphoro:thio:chloridate in presence of water and tert. amine | |
| NL186814C (nl) * | 1975-08-07 | 1991-03-01 | Dow Chemical Co | Werkwijze ter bereiding van een fosforthioaat of fenylfosfonothioaat. |
| CA1099278A (en) * | 1976-12-06 | 1981-04-14 | Raymond A. Simone | Manufacture of substituted phenyl phosphates involving use of phase transfer catalysts |
| GB2011415B (en) * | 1977-12-27 | 1982-06-30 | Ciba Geigy Ag | Process for the production of thiophosphoric acid esters |
-
1987
- 1987-11-16 ES ES198787116893T patent/ES2038981T3/es not_active Expired - Lifetime
- 1987-11-16 EP EP87116893A patent/EP0277292B1/en not_active Expired - Lifetime
- 1987-11-16 DE DE8787116893T patent/DE3769969D1/de not_active Expired - Fee Related
- 1987-11-17 IL IL84507A patent/IL84507A0/xx unknown
- 1987-11-20 DK DK612187A patent/DK168442B1/da not_active IP Right Cessation
- 1987-11-23 AU AU81479/87A patent/AU603843B2/en not_active Ceased
- 1987-11-23 CA CA000552450A patent/CA1310643C/en not_active Expired - Lifetime
- 1987-12-14 NZ NZ222896A patent/NZ222896A/xx unknown
- 1987-12-18 BR BR8707053A patent/BR8707053A/pt not_active Application Discontinuation
- 1987-12-21 KR KR1019870014597A patent/KR900003395B1/ko not_active IP Right Cessation
- 1987-12-21 RU SU874203816A patent/RU1801112C/ru active
- 1987-12-21 HU HU875911A patent/HU202875B/hu not_active IP Right Cessation
- 1987-12-22 JP JP62325128A patent/JPS63166896A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100775914B1 (ko) * | 2005-09-06 | 2007-11-15 | 중앙대학교 산학협력단 | 커패시터 및 그 제조방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ222896A (en) | 1989-12-21 |
| HUT48261A (en) | 1989-05-29 |
| AU8147987A (en) | 1988-06-23 |
| EP0277292B1 (en) | 1991-05-08 |
| RU1801112C (ru) | 1993-03-07 |
| DE3769969D1 (de) | 1991-06-13 |
| IL84507A0 (en) | 1988-04-29 |
| JPS63166896A (ja) | 1988-07-11 |
| EP0277292A1 (en) | 1988-08-10 |
| CA1310643C (en) | 1992-11-24 |
| DK168442B1 (da) | 1994-03-28 |
| DK612187A (da) | 1988-06-23 |
| HU202875B (en) | 1991-04-29 |
| BR8707053A (pt) | 1989-07-18 |
| ES2038981T3 (es) | 1993-08-16 |
| DK612187D0 (da) | 1987-11-20 |
| KR900003395B1 (ko) | 1990-05-18 |
| AU603843B2 (en) | 1990-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR860006448A (ko) | 트리아진유도체의 제조 방법 및 그것을 유효 성분으로하는 제초제 | |
| KR860008981A (ko) | 질소함유 헤테로고리 화합물의 제조방법 | |
| KR880007487A (ko) | 피리미디닐 오가노포스페이트를 제조하는 방법 | |
| KR830007539A (ko) | 시스테인 유동체의 분자내 또는 분자간 이황화물의 제조방법 | |
| KR860008987A (ko) | 2- 카르복시피라진 4-옥시드의 제조방법 | |
| KR840006480A (ko) | 유기화합물 및 이의 제조방법 | |
| KR830007580A (ko) | 신규 피리미딘 유도체의 제조방법 | |
| KR870002100A (ko) | 설포닐이소(티오)우레아 유도체의 제조방법 | |
| KR850002979A (ko) | 1,2,3-트리티안화합물의 신규 제조방법 | |
| KR850006191A (ko) | 티오시아노 피리미딘 유도체의 제조방법 | |
| KR870003102A (ko) | 트리아진 유도체의 제조방법 및 그것을 유효성분으로 하는 제초제 | |
| KR830009113A (ko) | 6-(2-아미노-2-페닐아세트아미도) 페니실란산 1,1-디옥소페니실라노일옥시메틸의 제조방법 | |
| KR860007245A (ko) | 피페라지닐메틸-1,2,4-트리아졸일메틸-카빈올의 제조방법 | |
| KR870002153A (ko) | α-시아노-(디)티오포스폰산 에스테르의 제조 방법 | |
| KR880005115A (ko) | 디페닐 에테르 제초제 | |
| KR870002093A (ko) | 설포닐이소(티오) 우레아의 제조방법 | |
| KR840000504A (ko) | N- 페닐피라졸 유도체의 제조방법 | |
| KR900006295A (ko) | 할로게노-4-메틸피라졸류 및 그의 제조방법 | |
| KR840001957A (ko) | 신규의 이소프로필 아미노 피리미딘 유도체의 제조방법 | |
| KR900006299A (ko) | 비고리 피리미딘 유도체의 제조방법 | |
| KR900001687A (ko) | 오메프라졸염의 제조방법 | |
| KR870002155A (ko) | 디아자포스포린의 제조방법 | |
| KR840004421A (ko) | 4-(치환된 알킬)-n-(1,3-디티올란-2-일리덴) 아닐린의 제조방법 | |
| KR900006279A (ko) | N,n'-디티오비스(설폰아미드)의 합성방법 | |
| KR890014499A (ko) | N-아미노-n'-메틸피페라진의 새로운 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| LAPS | Lapse due to unpaid annual fee |