KR880006359A - 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 - Google Patents

사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 Download PDF

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Publication number
KR880006359A
KR880006359A KR870013131A KR870013131A KR880006359A KR 880006359 A KR880006359 A KR 880006359A KR 870013131 A KR870013131 A KR 870013131A KR 870013131 A KR870013131 A KR 870013131A KR 880006359 A KR880006359 A KR 880006359A
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t11ts
sheep
human
immunized
ser
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KR870013131A
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English (en)
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휘니그 토마스
티펜탈러 게오르그
미트나흐트 리타
뫼이어 스테펜
Original Assignee
하인리히 벡커, 베른 하르트 벡크
훽스트 아크티엔게젤샤프트
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Publication of KR880006359A publication Critical patent/KR880006359A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

사람의 T11TS를 제조하기 위한 중간물질로서의 균일한 양 T11TS및 이의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 서역식(Ⅰ)의 아미노산 조성물 및 서열식(Ⅰ)의 N-말단을 갖는 균질한 양 T11TS 및 이의 변형체.
    VaL/Phe-Ser- GLn/Ser-ASP-ILe-Tyr-GLy-ALa-Met-Asn-GLy-Y-VaL-Thr-Phe-Tyr-VaL-Ser-Glu-Ser-Gln-Phhe-Thr-GLu-ILe-Met-Lys
    상기 서열식(Ⅱ)에서 X및 Y는 천연아미노산을 나타내고, Y는 바람직하게는 세린이다.
  2. 동물을 균질한 양 T11TS로 면역시킴을 특징으로 하여, 양 T11TS 및 사람의 T11TS에 대한 항체를 함유하는 특이적 항체를 제조하는 방법.
  3. 제2항에 있어서, 토끼(rabit)를 면역시키는 방법.
  4. 적합한 종류의 동물을 균질한 양 T11TS로 면역시키고, 항 혈청중의 항체를 사람의 T11TS를 면역학적으로 측절하는 방법.
  5. 제4 항에 있어서, 토끼를 면역시키는 방법.
  6. 제2항 및 3항에 청구된 방법에 의해 수득할 수 있는 양 T11TS및 사람의 T11TS에 대한 항체를 함유하는 특이적 항체.
  7. 제4항 또는 5항에 청구된 방법에 의해 수득할 수 있는 60,000의 분자량을 갖는 사람의 양 T11TS당단백질.
  8. 면역조절제로서, 및 모노클로날 항체의 제조를 위한 제1항 및 7항에 청구된 사람 및/또는 양 T11TS 및 이의 변형체의 용도.
  9. 양 T11TS에 대한 모노클로날 항체를 이용하여 양의 적혈구의 분해생성물로부터 양 T11TS를 농축 시키고, 경우에 따라 겔 전기영동에 의해 정제시킴을 특징으로 하여, 제1항에 청구된 균질한 양 T11TS를 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR870013131A 1986-11-22 1987-11-21 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 KR880006359A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3639920.5 1986-11-22
DE19863639920 DE3639920A1 (de) 1986-11-22 1986-11-22 Homogenes schaf-t11ts als zwischenprodukt zur herstellung von menschlichem t11ts und dessen verwendung

Publications (1)

Publication Number Publication Date
KR880006359A true KR880006359A (ko) 1988-07-22

Family

ID=6314535

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870013131A KR880006359A (ko) 1986-11-22 1987-11-21 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도

Country Status (9)

Country Link
EP (1) EP0268995A3 (ko)
JP (1) JPS63150228A (ko)
KR (1) KR880006359A (ko)
DE (1) DE3639920A1 (ko)
DK (1) DK610387A (ko)
IE (1) IE873143L (ko)
IL (1) IL84549A0 (ko)
PT (1) PT86174B (ko)
ZA (1) ZA878695B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660312B2 (en) * 1991-06-06 1995-06-22 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha LFA-3-like protein, derivatives thereof, genes thereof and processes for preparing the same

Also Published As

Publication number Publication date
EP0268995A2 (de) 1988-06-01
EP0268995A3 (de) 1990-04-18
DK610387A (da) 1988-05-23
IE873143L (en) 1988-05-22
DE3639920A1 (de) 1988-06-01
IL84549A0 (en) 1988-04-29
PT86174B (pt) 1990-08-31
PT86174A (de) 1987-12-01
DK610387D0 (da) 1987-11-20
JPS63150228A (ja) 1988-06-22
ZA878695B (en) 1988-05-20

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