KR880002839A - 신규한 α-치환된 케토니트론 유도체 - Google Patents

신규한 α-치환된 케토니트론 유도체 Download PDF

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Publication number
KR880002839A
KR880002839A KR870009309A KR870009309A KR880002839A KR 880002839 A KR880002839 A KR 880002839A KR 870009309 A KR870009309 A KR 870009309A KR 870009309 A KR870009309 A KR 870009309A KR 880002839 A KR880002839 A KR 880002839A
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South Korea
Prior art keywords
compound
phenyl
oxide
methyl
ethanimine
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KR870009309A
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English (en)
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에스티이. 죠지 바실
비이.멀렌 죠지
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마델린 알.락스니스
펜왈트 코포레이션
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Application filed by 마델린 알.락스니스, 펜왈트 코포레이션 filed Critical 마델린 알.락스니스
Publication of KR880002839A publication Critical patent/KR880002839A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

신규한 α-치환된 케토니트론 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (24)

  1. 일반식(Ⅰ)의 화합물,
    상기 식에서, R1은 2-나프틸, 2-푸라닐, 2-티에닐, 페닐, 및 할로겐, 저급 알킬, 저급 알콕시 또는 이들의 조합에 의해 치환된 하나 또는 그 이상의 메타 및 파라 수소를 갖는 치환된 페닐중에서 선택되고, R2는 수소 및 페닐중에서 선택되며, X는 질소 및 메틸(CH=) 그룹중에서 선택된다.
  2. 제1항에 있어서, R1은 페닐 또는 치환된 페닐이고, R2는 수소이며, X는 메틴인 화합물.
  3. 제2항에 있어서, 2-(1H-이미다졸-1-일)-N-메틸-1-페닐에탄이민 N-옥사이드의 화합물.
  4. 제2항에 있어서, 1-(4-클로로페닐)-2-(1H-아미다졸-1-일)-N-메틸에탄이민 N-옥사이드의 화합물.
  5. 제2항에 있어서, 1-(4-플루오로페닐)-2-(1H-아미다졸-1-일)-N-메틸에탄이민 N-옥사이드의 화합물.
  6. 제2항에 잇어서, 2-(1H-이미다졸-1-일)-1-(4-메톡시페닐)-N-메틸에탄이미 N데옥사이드의 화합물.
  7. 제2항에 있어서, 2-(1H-이미다졸-1-일)-1-(3-메톡시페닐)-N-메틸에탄이민 N-옥사이드의 화합물.
  8. 제2항에 있어서, 2-(1H-아미다졸-1-일)-N-메틸-1-(3-메틸페닐)에탄이민 N-옥사이드의 화합물
  9. 제2항에 있어서, 1-(4-클로로-3-메틸페닐)-2-(1H-이미다졸-1-일)-N-메틸에탄이민 N-옥사이드의 화합물.
  10. 제1항에 있어서, R1이 페닐 또는 치한된 페닐이고, R2는 페닐이며, X는 메틴인 화합물.
  11. 제10항에 있어서, 2-(1H-이미다졸-1-일)-1-페닐-N-(페닐메틸)에탄인민 N-옥사이드의 화합물.
  12. 제10항에 있어서, 1-(4-플루오로페닐)-2-(1H-이미다졸-1-일)-N-(페닐메틸)에탄이민 N-옥사이드의 화합물.
  13. 제1항에 있어서, R1이 페닐 또는 치환된, 페닐이고 R2는 수소이며 X는 질소인 화합물.
  14. 제13항에 있어서, N-메틸-1-페닐-2-(1H-1, 2, 4-트리아졸-1-일)에탄이민 N-옥사이드의 화합물.
  15. 제13항에 있어서, 1-(4-클로로페닐)-N-메틸-2-(1H-1, 2, 4-트리아졸-1-일)-에탄이민 N-옥사이드의 화합물.
  16. 제13항에 있어서, 1-(4-메톡시페닐)-N-메틸-2-(1H-1, 2, 4-트리아졸-1-일)-에탄이민 N-옥사이드의 화합물.
  17. 제13항에 있어서, 1-(4-플루오로페닐)-N-메틸-2-(1H-1, 2, 4-트리아졸-1-일) -에탄이민 N-옥사이드의 화합물.
  18. 제13항에 있어서, N-메틸-1-(3-메틸페닐)-2-(1H-1, 2, 4-트리아졸-1-일)-에탄이민 N-옥사이드의 화합물.
  19. 제1항에 있어서, R1이 2-나프틸이고 R2가 수소이며 X가 메틴인 화합물.
  20. 제19항에 있어서, 2-(1H-이미다졸-1-일)-N-메틸-1-(2-나프틸)에탄이민 N-옥사이드의 화합물.
  21. 제1항에 있어서, R1이 2-푸라닐이고, R2가 수소이며 X가 메틴인 화합물.
  22. 제21항에 있어서, 1-(2-푸라닐)-2-(1H-이미다졸-1-일)-N-메틸에탄이민 N-옥사이드의 화합물.
  23. 제1항에 있어서, R1이 2-티에닐이고, R2가 수소이며 X가 메틴인 화합물.
  24. 제23항에 있어서, 2-(1H-이미다졸-1-일)-N--메틸-1-(2-티에닐) 에탄이민 N-옥사이드의 화합물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR870009309A 1986-08-27 1987-08-26 신규한 α-치환된 케토니트론 유도체 KR880002839A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US900856 1986-08-27
US06/900,856 US4803282A (en) 1986-08-27 1986-08-27 Alpha-substituted ketonitrone derivatives

Publications (1)

Publication Number Publication Date
KR880002839A true KR880002839A (ko) 1988-05-11

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KR870009309A KR880002839A (ko) 1986-08-27 1987-08-26 신규한 α-치환된 케토니트론 유도체

Country Status (12)

Country Link
US (1) US4803282A (ko)
EP (1) EP0257289A3 (ko)
JP (1) JPS6357575A (ko)
KR (1) KR880002839A (ko)
AU (1) AU7445387A (ko)
DK (1) DK444687A (ko)
FI (1) FI873707A (ko)
IL (1) IL82805A0 (ko)
NO (1) NO873606L (ko)
NZ (1) NZ220570A (ko)
PH (1) PH22444A (ko)
ZA (1) ZA874515B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286698A (en) * 1989-04-25 1994-02-15 University Of Notre Dame Du Lac Metal oxide catalysts
CA2260825A1 (en) * 1996-07-19 1998-01-29 Centaur Pharmaceuticals, Inc. Furan nitrone compounds
ATE228123T1 (de) * 1998-01-16 2002-12-15 Centaur Pharmaceuticals Inc Thiophennitronderivate
JP2002509143A (ja) * 1998-01-16 2002-03-26 センター ファーマシューティカルズ， インコーポレイテッド チオエーテルフランニトロン化合物
FR2780404B1 (fr) * 1998-06-26 2001-04-13 Adir Nouveaux derives de nitrone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR3012460B1 (fr) 2013-10-25 2015-12-11 Michelin & Cie Composition de caoutchouc comprenant un elastomere dienique portant des fonctions imidazole reparties de facon aleatoire le long de la chaine
FR3012451B1 (fr) * 2013-10-25 2016-11-11 Michelin & Cie Compose 1,3-dipolaire portant une fonction imidazole
FR3012458B1 (fr) 2013-10-25 2015-10-30 Michelin & Cie Composition de caoutchouc comprenant un additif compose 1,3-dipolaire portant une fonction imidazole

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3016569A1 (de) * 1980-04-30 1981-11-05 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von alkylarylketoximethern
US4719306A (en) * 1986-08-27 1988-01-12 Pennwalt Corporation Substituted 3,5-diphenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines

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Publication number Publication date
DK444687A (da) 1988-02-28
JPS6357575A (ja) 1988-03-12
FI873707A0 (fi) 1987-08-26
FI873707A (fi) 1988-02-28
NO873606D0 (no) 1987-08-26
IL82805A0 (en) 1987-12-20
DK444687D0 (da) 1987-08-26
AU7445387A (en) 1988-03-03
PH22444A (en) 1988-09-12
NO873606L (no) 1988-02-29
EP0257289A2 (en) 1988-03-02
ZA874515B (en) 1988-05-25
NZ220570A (en) 1989-02-24
US4803282A (en) 1989-02-07
EP0257289A3 (en) 1989-02-15

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