KR880002685B1 - 6-[(사이클릭아미노)-알킬아미노]-테트라하이드로 트리아졸로[3,4-a]프탈라진 및 이의 제조방법 - Google Patents

6-[(사이클릭아미노)-알킬아미노]-테트라하이드로 트리아졸로[3,4-a]프탈라진 및 이의 제조방법 Download PDF

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Publication number
KR880002685B1
KR880002685B1 KR1019830004193A KR830004193A KR880002685B1 KR 880002685 B1 KR880002685 B1 KR 880002685B1 KR 1019830004193 A KR1019830004193 A KR 1019830004193A KR 830004193 A KR830004193 A KR 830004193A KR 880002685 B1 KR880002685 B1 KR 880002685B1
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KR
South Korea
Prior art keywords
tetrahydro
triazolo
phthalazine
compound
ethylamino
Prior art date
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Expired
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KR1019830004193A
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English (en)
Korean (ko)
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KR840006247A (ko
Inventor
폴 피트 노튼
앤 알렉산더 캐더린
Original Assignee
더 다우 케미칼 캄파니
리차드 고든 워터맨
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Publication of KR840006247A publication Critical patent/KR840006247A/ko
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Publication of KR880002685B1 publication Critical patent/KR880002685B1/ko
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019830004193A 1982-09-07 1983-09-06 6-[(사이클릭아미노)-알킬아미노]-테트라하이드로 트리아졸로[3,4-a]프탈라진 및 이의 제조방법 Expired KR880002685B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/414,766 US4487930A (en) 1982-09-07 1982-09-07 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines
US414766 1982-09-07

Publications (2)

Publication Number Publication Date
KR840006247A KR840006247A (ko) 1984-11-22
KR880002685B1 true KR880002685B1 (ko) 1988-12-20

Family

ID=23642869

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830004193A Expired KR880002685B1 (ko) 1982-09-07 1983-09-06 6-[(사이클릭아미노)-알킬아미노]-테트라하이드로 트리아졸로[3,4-a]프탈라진 및 이의 제조방법

Country Status (17)

Country Link
US (1) US4487930A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0104506B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5965092A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR880002685B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE23339T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU555725B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1204753A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3367393D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK160310C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES525368A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR78970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE55908B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL69659A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO833181L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ205493A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH18334A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA836551B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194310B (it) * 1983-07-12 1988-09-14 Lepetit Spa Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti
US5011835A (en) * 1990-02-07 1991-04-30 Merrell Dow Pharmaceuticals Inc. Substituted triazolopyridazines, pharmaceutical compositions and use
ES2194205T3 (es) 1996-07-25 2003-11-16 Merck Sharp & Dohme Derivados de triazolo-piridazina sustituidos como ligandos para los receptores gaba.
US6989080B2 (en) * 2003-06-19 2006-01-24 Albany International Corp. Nonwoven neutral line dryer fabric
PH12012501361A1 (en) 2009-12-31 2012-10-22 Centro Nac De Investigaciones Oncologicas Cnio Tricyclic compounds for use as kinase inhibitors
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
WO2013005041A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Tricyclic heterocyclic compounds as kinase inhibitors
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
WO2013005057A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) New compounds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA883836A (en) * 1971-10-19 H. De Ruiter Ernest Selective hydrogenation of tri- and tetrazoloisquinolines
US2484629A (en) * 1943-11-27 1949-10-11 Squibb & Sons Inc 2-sulfanilamido-4-alkoxymethyl-6-methyl-pyrimidines and their preparation
FR1248409A (fr) * 1957-06-13 1960-12-16 Bellon Labor Sa Roger Perfectionnements aux procédés de préparation de dérivés de la triazolo [4-3,b]pyridazine
US3096329A (en) * 1957-10-15 1963-07-02 Sterling Drug Inc Triazolo [b] pyridazines
US3079392A (en) * 1961-04-27 1963-02-26 Pesson Marcel Triazolo(4-3, b)pyridazines
NL128591C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1965-07-02
FR2068082A6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1969-11-27 1971-08-20 Guinard Pompes
US3915968A (en) * 1973-09-21 1975-10-28 Lepetit Spa Triazolopyridazines
JPS5516450B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-08-16 1980-05-02
US4016162A (en) * 1974-08-27 1977-04-05 Gruppo Lepetit S.P.A. 6-Morpholino-3-substituted phenyl-S-triazolo[4,3-b]pyridazines
US4136182A (en) * 1976-05-26 1979-01-23 The Dow Chemical Company Triazolopyridazines used to alleviate bronchial spasms
CA1080712A (en) * 1976-09-22 1980-07-01 Jay D. Albright Hypotensive agents
US4112095A (en) * 1976-10-07 1978-09-05 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents
US4272535A (en) * 1978-07-31 1981-06-09 Schering Corporation 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents
GR70309B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1979-10-29 1982-09-08 Dow Chemical Co

Also Published As

Publication number Publication date
AU1871383A (en) 1984-03-15
EP0104506A1 (en) 1984-04-04
EP0104506B1 (en) 1986-11-05
PH18334A (en) 1985-06-05
ATE23339T1 (de) 1986-11-15
JPH0378396B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-12-13
IE832096L (en) 1984-03-07
IE55908B1 (en) 1991-02-14
DK160310B (da) 1991-02-25
NZ205493A (en) 1985-09-13
DK404383A (da) 1984-03-08
ZA836551B (en) 1984-04-25
ES8601985A1 (es) 1985-12-01
KR840006247A (ko) 1984-11-22
US4487930A (en) 1984-12-11
DE3367393D1 (de) 1986-12-11
AU555725B2 (en) 1986-10-09
ES525368A0 (es) 1985-12-01
CA1204753A (en) 1986-05-20
NO833181L (no) 1984-03-08
DK160310C (da) 1991-07-29
IL69659A0 (en) 1983-12-30
IL69659A (en) 1986-08-31
GR78970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-10-02
DK404383D0 (da) 1983-09-06
JPS5965092A (ja) 1984-04-13

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