KR880000434A - 3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법 - Google Patents

3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법 Download PDF

Info

Publication number
KR880000434A
KR880000434A KR1019870006527A KR870006527A KR880000434A KR 880000434 A KR880000434 A KR 880000434A KR 1019870006527 A KR1019870006527 A KR 1019870006527A KR 870006527 A KR870006527 A KR 870006527A KR 880000434 A KR880000434 A KR 880000434A
Authority
KR
South Korea
Prior art keywords
propyl
amino
dihydro
dione
pyrimidinedione
Prior art date
Application number
KR1019870006527A
Other languages
English (en)
Inventor
페르 군나트 크옐린
Original Assignee
칼 거스 타프 요한슨
악티에볼라게트 드라코
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 칼 거스 타프 요한슨, 악티에볼라게트 드라코 filed Critical 칼 거스 타프 요한슨
Publication of KR880000434A publication Critical patent/KR880000434A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. a) 촉매 존재하에, 포름산 중에서 6-아미노-1-n-2,4-(1H,3H)-피리미딘디온을 아질산 나트륨으로 처리하여 6-아미노-5-포름아미도-1-n-프로필-2,4-(1H,3H)-피리미딘디온을 생성하고,
    b) 생성된 6-아미노-5-포름아미도-1-n-프로필-2,4-(1H,3H)-피리미딘디온 상에서 고리 폐쇄반응을 행하여 3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온을 생성시킴을 특징으로 하는 3,47-디히드로-3-n-프로필-1H-푸린-2,6-디온의 제조방법.
  2. 제 1 항에 있어서, 포름산의 매개에 의해 6-아미노-1-n-프로필-2,4-(1H,3H)-피리미딘디온을 6-아미노-5-포름아미도-1-n-프로필-2,4-(1H,3H)-피리미디온으로 전환시킴을 특징으로 하는 방법.
  3. 제 1 항에 있어서, 단계 a)의 촉매로서 Pt/C, PtO2, Pd/C 또는 Rh/C를 사용함을 특징으로 하는 방법.
  4. 6-아미노-5-포름아미도-1-n-프로필-2,4-(1H,3H)-피리미디온을 생성시키기 위한 6-아미노-1-n-프로필-2,4-(1H,3H)-피리미디온의 화학 반응에 있어서 포름산의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870006527A 1986-06-27 1987-06-26 3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법 KR880000434A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8602887-5 1986-06-27
SE8602887A SE8602887D0 (sv) 1986-06-27 1986-06-27 New chemical method

Publications (1)

Publication Number Publication Date
KR880000434A true KR880000434A (ko) 1988-03-25

Family

ID=20364961

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870006527A KR880000434A (ko) 1986-06-27 1987-06-26 3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법

Country Status (11)

Country Link
US (1) US4777255A (ko)
EP (1) EP0252043A1 (ko)
JP (1) JPS638385A (ko)
KR (1) KR880000434A (ko)
AU (1) AU7383487A (ko)
DK (1) DK299487A (ko)
FI (1) FI872818A (ko)
NO (1) NO872624L (ko)
PH (1) PH22737A (ko)
PT (1) PT85185A (ko)
SE (1) SE8602887D0 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229195B (it) * 1989-03-10 1991-07-25 Poli Ind Chimica Spa Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
DE4410678A1 (de) * 1994-03-28 1995-10-05 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 5-Formylamino-pyrimidinen
CN107141290A (zh) * 2017-06-12 2017-09-08 桑迪亚医药技术（上海）有限责任公司 一种1,3‑二乙基‑3,7‑二氢嘌呤‑2,6‑二酮的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2852516A (en) * 1957-04-17 1958-09-16 Monsanto Chemicals Method for preparing amino-formamido compounds
SE7810946L (sv) * 1978-10-20 1980-04-21 Draco Ab Metod att behandla kronisk obstruktiv luftvegssjukdom

Also Published As

Publication number Publication date
US4777255A (en) 1988-10-11
EP0252043A1 (en) 1988-01-07
AU7383487A (en) 1988-01-07
FI872818A0 (fi) 1987-06-25
PH22737A (en) 1988-11-28
DK299487D0 (da) 1987-06-12
SE8602887D0 (sv) 1986-06-27
JPS638385A (ja) 1988-01-14
FI872818A (fi) 1987-12-28
NO872624D0 (no) 1987-06-23
DK299487A (da) 1987-12-28
NO872624L (no) 1987-12-28
PT85185A (en) 1987-07-01

Similar Documents

Publication Publication Date Title
KR880001558A (ko) 결정성 트리브로모스티렌의 제조 방법
DE60004186D1 (de) Verfahren zur herstellung von 1,1,1,3,3-pentafluorpropen und 1,1,1,3,3-pentafluorpropan
ES2006296A6 (es) Un procedimiento mejorado para preparar alcoholes.
KR880000434A (ko) 3,7-디히드로-3-n-프로필-1H-푸린-2,6-디온(엔프로필린)의 신규의 제조방법
DE50204071D1 (de) Verfahren zur Herstellung von Metallformat-Ameisensäure-Mischungen
YU47120B (sh) Postupak za dobijanje 4-(3,4-dihlorfenil)-4-fenilbutanske kiseline
KR880001569A (ko) 2-하이드록시나프탈렌-6-카르복시산의 제조방법
KR880011054A (ko) 산화티탄 담지 팔라듐 촉매의 제조방법
KR910007917A (ko) Bmy 21502의 대규모 제조방법
KR880006156A (ko) 메틸 이소부틸 케톤의 제조 방법
ATE13760T1 (de) Verfahren zur herstellung von phydroxybenzylnitrilen oder p-hydroxybenzylaminen.
KR830005080A (ko) 산화된 화합물의 제조 방법
KR850003386A (ko) 1,3-비스(3-아미노페녹시)-벤젠의 제조방법
ATE69031T1 (de) Verfahren zur umwandlung von kohlenstoffmonoxid und wasser in wasserstoff und kohlenstoffdioxid.
ES477208A1 (es) Proceso para producir aldehidos aromaticos.
KR880000411A (ko) 벤조구아나민 유도체의 제법
SU564257A1 (ru) Способ получени кислорода
KR870009980A (ko) 4' -히드록시바이페닐-4-카르복실산의 제조방법
KR830005079A (ko) 아세트알데히드와 에탄올의 루테늄 촉매 제조방법
KR910007856A (ko) 질산(12hno₃)을 이용한 수산[(cooh)₂₂2h₂o)]의 제조방법
SU582252A1 (ru) Способ получени производных 5-фенацил2,,3-имидазол-2,4-диона
FR2226388A1 (en) Epsilon-aminocaproamide prodn in liq. ammonia - by catalytic hydrogen-ation of epsilon -nitrocaproamide under pressure
KR860000376A (ko) 인삼박(粕)을 이용한 제빵 효모의 제조방법
KR910011742A (ko) 신남산의 제조방법
ES2038209T3 (es) Procedimiento para la obtencion de 1-aminoantraquinonas.

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid