KR830009091A - 5-플루오로 우라실 유도체의 제조방법 - Google Patents
5-플루오로 우라실 유도체의 제조방법 Download PDFInfo
- Publication number
- KR830009091A KR830009091A KR1019820001266A KR820001266A KR830009091A KR 830009091 A KR830009091 A KR 830009091A KR 1019820001266 A KR1019820001266 A KR 1019820001266A KR 820001266 A KR820001266 A KR 820001266A KR 830009091 A KR830009091 A KR 830009091A
- Authority
- KR
- South Korea
- Prior art keywords
- preparing
- uracil derivatives
- fluoro uracil
- compound
- base
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 2
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical class FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 3
- FVTWJXMFYOXOKK-UHFFFAOYSA-N 2-fluoroacetamide Chemical compound NC(=O)CF FVTWJXMFYOXOKK-UHFFFAOYSA-N 0.000 claims 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 229910052744 lithium Inorganic materials 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 구조식(XII)의 화합물과 플루오로 아세트아마이드(FCH2CONH2)를 염기 존재하에서 핵전환 반응시키는 것을 특징으로 하여 중간체(II)의 화합물을 제조하여 목적물(I)을 제조하는 방법.
- 1항에서 염기는또는 리튬 디이소푸로필 아마이드(LDA)를 의미하며 R은 CH3,C2H5,C3H7,C4H9이 적당하다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019820001266A KR830002379B1 (ko) | 1982-03-25 | 1982-03-25 | 5-플루오로 우라실 유도체의 제조방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019820001266A KR830002379B1 (ko) | 1982-03-25 | 1982-03-25 | 5-플루오로 우라실 유도체의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR830002379B1 KR830002379B1 (ko) | 1983-10-25 |
| KR830009091A true KR830009091A (ko) | 1983-12-17 |
Family
ID=19224246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019820001266A KR830002379B1 (ko) | 1982-03-25 | 1982-03-25 | 5-플루오로 우라실 유도체의 제조방법 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR830002379B1 (ko) |
-
1982
- 1982-03-25 KR KR1019820001266A patent/KR830002379B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR830002379B1 (ko) | 1983-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| G160 | Decision to publish patent application | ||
| O073 | Decision to grant registration after opposition [patent]: decision to grant registration | ||
| O132 | Decision on opposition [patent] | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19930330 Year of fee payment: 12 |
|
| EXPY | Expiration of term |