KR830006323A - Preparation of Glucosyl Moranoline Derivatives - Google Patents

Preparation of Glucosyl Moranoline Derivatives Download PDF

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Publication number
KR830006323A
KR830006323A KR1019810001798A KR810001798A KR830006323A KR 830006323 A KR830006323 A KR 830006323A KR 1019810001798 A KR1019810001798 A KR 1019810001798A KR 810001798 A KR810001798 A KR 810001798A KR 830006323 A KR830006323 A KR 830006323A
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South Korea
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glucosyl
preparation
general formula
moranoline
following general
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KR1019810001798A
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Korean (ko)
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KR850000475B1 (en
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마쓰무라신고
히로시 애노모또
요시아끼 아오야기
요오지 애즈래
요시아끼 요시구니
마사히로 야기
노부도시 오지마
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모리시따 히로시
닛본 신야구 가부시기 가이샤
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Publication of KR830006323A publication Critical patent/KR830006323A/en
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Publication of KR850000475B1 publication Critical patent/KR850000475B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

내용 없음No content

Description

글르코시일 모라노린 유도체의 제법Preparation of Glucosyl Moranoline Derivatives

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 메틸 올리고 글르코시일 모라노린에 α-1,4-글르칸글르코 하이드로라아제를 작용했을 때의 각 화합물의 분해%를 나타낸다.FIG. 1 shows the percent decomposition of each compound when α-1,4-glucanglucohydrolase is acted on methyl oligo glycosyl moranoline.

도면에서 - · -는 말토스를, -×-는 4-(α-D-글르코시일)-N-메틸모라노린을, -△-는 4-(α-D-말트시일)-N-메틸모라노린을, -△-은 4-(α-D-말트트리오시일)-N-메틸모라노린을, -○-는 4-(α-D-말트테트라오 시일)-N-메틸모라노린을 표시한다.In the figure---is maltose, -x- is 4- (α-D-glycosyl) -N-methylmoranoline, -Δ- is 4- (α-D-maltyl) -N- Methylmoranoline, -Δ- is 4- (α-D-maltiooxyl) -N-methylmoranoline,-○-is 4- (α-D-maltetraoyl) -N-methylmoranoline Is displayed.

제 2, 제3도는 실시예 2에 있어서의 α-1,4-글르칸글르코하이드로라아제를 반응시키는 전후의 고속 액체크로마트그래피(워터즈 사제 ALC/GPC-244형)의 결과이다.2 and 3 show the results of high-speed liquid chromatography (type ALC / GPC-244 manufactured by Waters) before and after reacting α-1,4-glucan glucohydrolase in Example 2. FIG.

M-본더팩-NH2컬럼을 사용하여 아세트니트릴 : 물 70 : 30, 1.5ml/분으로 전개하여, 시마즈(島津)제크마트팩 C-RIA형으로 분석했다. 종축은 시차(示差)굴절률, 횡축은 전개시간, 도면의 수자는 리텐션타임(분), S는 소르벤트, A, B, C, D, E, F, G, H, I는 N-메틸올리고 글르코시일 모라노린을 표시한다.Using an M-Bonderpack-NH 2 column, the mixture was developed with acetonitrile: water: 70: 30, 1.5 ml / min, and analyzed by Shimadzu Zekmartpak C-RIA type. The vertical axis represents the parallax refractive index, the horizontal axis represents the development time, the number in the drawing is the retention time in minutes, S is the sorbent, A, B, C, D, E, F, G, H, and I are N-methyl Oligo Glycosyl Moranoline is indicated.

Claims (1)

다음의 일반식(Ⅰ)General formula (Ⅰ) (R은 수소 또는 저급알킬기를 나타내고 n은 정수를 나타낸다.)(R represents hydrogen or lower alkyl group and n represents an integer.) 로 나타낼 수 있는 것중, n이 0∼20의 화합물 및 다음의 일반식(Ⅲ)Among the compounds which can be represented by n is 0 to 20 and the following general formula (III) (R는 상기와 동일)으로 표시되는 화합물을 함유한 혼합물(단(Ⅰ)에 있어서 n=0의 화합물만을 함유하는 경우를 제외한다.)을 함유하는용액에 직접 또는 필요에 따라 산 카티온 교환체를 첨가한 후, α-1,4-글르칸글르코 하이드로 라아제를 작용시키는 것을 특징으로 하는 다음의 일반식(Ⅱ)Acid cationic exchange directly or as needed with a solution containing a mixture containing the compound represented by (R is the same as above) except that only the compound of n = 0 is contained in (I). After addition of a sieve, the following general formula (II) characterized in that α-1,4-glycanglucohydrolase is reacted (R는 상기와 동일함)로 표시되는 글르코시일모라노린 유도체의 제법.(R is the same as the above) A method for producing a glycosyl moranoline derivative. ※참고사항:최초출원 내용에 의하여 공개하는 것임.※ Note: This is to be disclosed based on the first application.
KR1019810001798A 1980-09-22 1981-05-23 Method of preparing for the glycocyl moranoline derivative KR850000475B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55131949A JPS602038B2 (en) 1980-09-22 1980-09-22 Method for producing glucosylmoranoline derivatives
JP131949 1980-09-22

Publications (2)

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KR830006323A true KR830006323A (en) 1983-09-20
KR850000475B1 KR850000475B1 (en) 1985-04-08

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KR1019810001798A KR850000475B1 (en) 1980-09-22 1981-05-23 Method of preparing for the glycocyl moranoline derivative

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JP (1) JPS602038B2 (en)
KR (1) KR850000475B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62242692A (en) * 1986-04-15 1987-10-23 Nippon Shinyaku Co Ltd Production of moranoline derivative
JPS62242691A (en) * 1986-04-15 1987-10-23 Nippon Shinyaku Co Ltd Production of moranoline derivative

Also Published As

Publication number Publication date
JPS5758890A (en) 1982-04-08
KR850000475B1 (en) 1985-04-08
JPS602038B2 (en) 1985-01-18

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