KR830005191A - Method for producing furan derivative - Google Patents

Method for producing furan derivative Download PDF

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Publication number
KR830005191A
KR830005191A KR1019810000033A KR810000033A KR830005191A KR 830005191 A KR830005191 A KR 830005191A KR 1019810000033 A KR1019810000033 A KR 1019810000033A KR 810000033 A KR810000033 A KR 810000033A KR 830005191 A KR830005191 A KR 830005191A
Authority
KR
South Korea
Prior art keywords
formula
thiol
group
furan derivative
process according
Prior art date
Application number
KR1019810000033A
Other languages
Korean (ko)
Other versions
KR840002007B1 (en
Inventor
브래드셔 존
와트슨 크리디로 존
Original Assignee
배리 안토니 뉴삼
그랙소 그룹 리밋티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 배리 안토니 뉴삼, 그랙소 그룹 리밋티드 filed Critical 배리 안토니 뉴삼
Publication of KR830005191A publication Critical patent/KR830005191A/en
Priority to KR1019840005346A priority Critical patent/KR840002002B1/en
Application granted granted Critical
Publication of KR840002007B1 publication Critical patent/KR840002007B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Abstract

내용 없음No content

Description

푸란유도체의 제조방법Method for producing furan derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (6)

구조식(Ⅱ)의 티올을 구조식(Ⅲ)의 알킬화제와 반응시켜서 구조식(Ⅰ)의 푸란유도체를 제조하는 방법.A process for preparing a furan derivative of formula (I) by reacting a thiol of formula (II) with an alkylating agent of formula (III). 여기서 R1은 -CH2CH2L(L은 이탈기)기이고, R2는 수소원자이거나 R1과 R2모두가 질소원자에 부착되어서 에틸렌이미노기를 형성하기도 한다.R 1 is a -CH 2 CH 2 L (L is a leaving group), R 2 is a hydrogen atom or both R 1 and R 2 is attached to a nitrogen atom to form an ethyleneimino group. R1이 -CH2CH2L기이고 R2가 수소원자인 청구범위 1항과 같은 제조방법.A process according to claim 1 wherein R 1 is a -CH 2 CH 2 L group and R 2 is a hydrogen atom. R1R2N이 에틸렌이미노기인 청구범위 1항과 같은 제조방법.The method according to claim 1, wherein R 1 R 2 N is an ethyleneimino group. L이 할로겐원자인 청구범위 1 또는 2항과 같은 제조방법.A process according to claim 1 or 2, wherein L is a halogen atom. 구조식(Ⅱ)의 티올이 산부가염에서 원상태로 생성된 것인 청구범위 1-4항과 같은 제조방법.The thiol of formula (II) is produced in the original state in the acid addition salt as in claim 1-4. 구조식(Ⅱ)의 티올이 염기성 상태에서 이소티오우레와(Ⅳ)나 그것의 염으로부터 원상태로 생성된 것인 청구범위 1-4항과 같은 제조방법.A process according to claim 1-4, wherein the thiol of formula II is produced intact from isothiourea (IV) or a salt thereof in a basic state. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019810000033A 1980-01-08 1981-01-08 Process for the preparation of a furan derivative KR840002007B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840005346A KR840002002B1 (en) 1980-01-08 1984-08-31 Process for preparing aziridine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8000580 1980-01-08
GB8000580 1980-01-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019840005346A Division KR840002002B1 (en) 1980-01-08 1984-08-31 Process for preparing aziridine derivatives

Publications (2)

Publication Number Publication Date
KR830005191A true KR830005191A (en) 1983-08-03
KR840002007B1 KR840002007B1 (en) 1984-10-27

Family

ID=10510510

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810000033A KR840002007B1 (en) 1980-01-08 1981-01-08 Process for the preparation of a furan derivative

Country Status (5)

Country Link
JP (1) JPS56103171A (en)
KR (1) KR840002007B1 (en)
BE (1) BE886997A (en)
CH (1) CH654830A5 (en)
GB (1) GB2067991B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0055625B1 (en) * 1980-12-30 1985-05-02 Glaxo Group Limited Process for the preparation of a furan derivative
JPS57134476A (en) * 1980-12-30 1982-08-19 Glaxo Group Ltd Manufacture of furan derivatives
JPS57150640A (en) * 1981-02-03 1982-09-17 Glaxo Group Ltd Therapeutical nitrovinyl derivatives and medicinal composition containing them
US4399293A (en) * 1981-02-20 1983-08-16 Glaxo Group Limited Process for the preparation of a furan derivative
DE3213509A1 (en) * 1982-04-10 1983-10-20 Basf Ag, 6700 Ludwigshafen N-SUBSTITUTED IMIDAZOLE DERIVATIVES, THEIR PRODUCTION, THE MEDICINES CONTAINING THEM AND THEIR USE
YU45634B (en) * 1983-07-15 1992-07-20 Richter Gedeon Vegyeszeti Gyar R.T. PROCESS FOR THE PREPARATION OF 1- / 2- / 5-DIMETHYLAMINOMETHYL-2- (FURYLMETHYLTHIOL) -ETHYL / -AMINO-1-METHYLAMINO-2-NITROETHYLENE HYDROCHLORIDE
US5686588A (en) * 1995-08-16 1997-11-11 Yoo; Seo Hong Amine acid salt compounds and process for the production thereof

Also Published As

Publication number Publication date
CH654830A5 (en) 1986-03-14
JPH0224827B2 (en) 1990-05-30
KR840002007B1 (en) 1984-10-27
GB2067991B (en) 1983-10-19
GB2067991A (en) 1981-08-05
BE886997A (en) 1981-07-08
JPS56103171A (en) 1981-08-18

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