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C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
C07D239/94—Nitrogen atoms
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Organic Chemistry
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Plural Heterocyclic Compounds
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Abstract
내용 없음No content
Description
4-아닐리노퀴나졸린 유도체의 제조방법Method for preparing 4-anilinoquinazoline derivative
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음This content is subject to disclosure, so the full text is not included.
Claims (1)
일반식(II)을 표시되는 할로퀴나졸린 유도체를 일반식(III)으로 표시되는 아닐린 또는 아닐린 유도체와 반응시켜 일반식(I)로 표시되는 화합물 및 의약적으로 허용되는 그 산부가염을 제조하는 4-아닐리노퀴나졸린 유도체 제조방법.4 to prepare a compound represented by the general formula (I) and a pharmaceutically acceptable acid addition salt thereof by reacting a haloquinazoline derivative represented by the general formula (II) with an aniline or an aniline derivative represented by the general formula (III). -Anilinoquinazoline derivative production method.(상기 일반식들에서 R2및 R3가 둘다 수소인 경우 R1이 6-위치의 수소 또는 염소 원자를 나타내는 것이 아니라는 전제하에,(In the above general formulas, when R 2 and R 3 are both hydrogen, under the premise that R 1 does not represent a 6-position hydrogen or a chlorine atom,R1은 수소원자, 할로겐원자, 트리플루오로메틸기 또는 니트로기를 나타내고,R 1 represents a hydrogen atom, a halogen atom, a trifluoromethyl group or a nitro group,R2는 수소원자, 알킬기, 알톡시기 또는 할로겐원자를 나타내며,R 2 represents a hydrogen atom, an alkyl group, an ALToxy group or a halogen atom,R3는 수소원자 또는 알킬기를 나타내고,R 3 represents a hydrogen atom or an alkyl group,X는 할로겐원자를 나타낸다)X represents a halogen atom)※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed according to the contents of the initial application.
KR1019790003111A1979-09-111979-09-11
Method for preparing 4-anilinoquinazoline derivatives
KR830001347B1
(en)