KR830000248A - 세파로스포린 항생물질의 제조방법 - Google Patents

세파로스포린 항생물질의 제조방법 Download PDF

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Publication number
KR830000248A
KR830000248A KR1019770000334A KR770000334A KR830000248A KR 830000248 A KR830000248 A KR 830000248A KR 1019770000334 A KR1019770000334 A KR 1019770000334A KR 770000334 A KR770000334 A KR 770000334A KR 830000248 A KR830000248 A KR 830000248A
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KR
South Korea
Prior art keywords
structural formula
following structural
sepharosporin
fur
compound
Prior art date
Application number
KR1019770000334A
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English (en)
Other versions
KR830001521B1 (ko
Inventor
그리그손 미카엘
브룩 스카이스 리카르드
Original Assignee
헤롤드 왈터 마틴
글락소 라보라토리즈
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 헤롤드 왈터 마틴, 글락소 라보라토리즈 filed Critical 헤롤드 왈터 마틴
Priority to KR7700334A priority Critical patent/KR830001521B1/ko
Publication of KR830000248A publication Critical patent/KR830000248A/ko
Application granted granted Critical
Publication of KR830001521B1 publication Critical patent/KR830001521B1/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

내용 없음

Description

세파로스포린 항생물질의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. A)(6R,7R)-3-카바모일옥시메틸-7-[(Z)-2-(푸르-2-일)-2-메톡시이미노아세트아미도]세프-3-엠-4-카복실산(즉, 세푸록심) 또는 그의 염을 다음 구조식(II)인 할로에스텔과 반응시키거나,
  2. 또는
  3. B) 다음 구조식(III)인 화합물 또는 그의 산부가염 또는 N-실린 유도체를 (Z)-2-(푸르-2-일)-2-메톡시이미노 아세틴산 또는 그의 반응성이 큰 유도체로 아실화시킴을 특징으로 하는 다음 구조식(I)인 화합물의 제조방법.
  4. 상기 구조식에서
  5. R은 탄소수 1-4인 일급 또는 2급 알킬 그룹이고,
  6. X는 할로겐이다.
  7. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR7700334A 1977-02-15 1977-02-15 세팔로스포린 항생물질의 제조 방법 KR830001521B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR7700334A KR830001521B1 (ko) 1977-02-15 1977-02-15 세팔로스포린 항생물질의 제조 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR7700334A KR830001521B1 (ko) 1977-02-15 1977-02-15 세팔로스포린 항생물질의 제조 방법

Publications (2)

Publication Number Publication Date
KR830000248A true KR830000248A (ko) 1983-03-30
KR830001521B1 KR830001521B1 (ko) 1983-08-08

Family

ID=19203881

Family Applications (1)

Application Number Title Priority Date Filing Date
KR7700334A KR830001521B1 (ko) 1977-02-15 1977-02-15 세팔로스포린 항생물질의 제조 방법

Country Status (1)

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KR (1) KR830001521B1 (ko)

Also Published As

Publication number Publication date
KR830001521B1 (ko) 1983-08-08

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