KR830000085B1 - 5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법 - Google Patents

5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법 Download PDF

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Publication number
KR830000085B1
KR830000085B1 KR1019790001163A KR790001163A KR830000085B1 KR 830000085 B1 KR830000085 B1 KR 830000085B1 KR 1019790001163 A KR1019790001163 A KR 1019790001163A KR 790001163 A KR790001163 A KR 790001163A KR 830000085 B1 KR830000085 B1 KR 830000085B1
Authority
KR
South Korea
Prior art keywords
methyl
hydrogen
aza
product
androstan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019790001163A
Other languages
English (en)
Korean (ko)
Inventor
에이취. 라스머슨 게리
비. 알. 존스톤 데이비드
에프. 레인홀드 도날드
어튼 로오리이프
비. 좁슨 로날드
Original Assignee
제임스 에프. 너우톤
맬크 앤드 캄파니 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU45697/79A priority Critical patent/AU527030B2/en
Priority to NZ190119A priority patent/NZ190119A/en
Priority to ZA791752A priority patent/ZA791752B/xx
Priority to EP79101131A priority patent/EP0004949B1/en
Priority to CA000325640A priority patent/CA1142914A/en
Application filed by 제임스 에프. 너우톤, 맬크 앤드 캄파니 인코포레이티드 filed Critical 제임스 에프. 너우톤
Priority to KR1019790001163A priority patent/KR830000085B1/ko
Priority to JP4445879A priority patent/JPS54145669A/ja
Priority to IE765/79A priority patent/IE48127B1/en
Priority to US06/189,981 priority patent/US4377584A/en
Application granted granted Critical
Publication of KR830000085B1 publication Critical patent/KR830000085B1/ko
Priority to JP62231223A priority patent/JPS63152320A/ja
Priority to HK801/87A priority patent/HK80187A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
KR1019790001163A 1978-04-13 1979-04-12 5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법 Expired KR830000085B1 (ko)

Priority Applications (11)

Application Number Priority Date Filing Date Title
AU45697/79A AU527030B2 (en) 1978-04-13 1979-04-04 4-aza-17-substituted-5a-androstan-3-ones
NZ190119A NZ190119A (en) 1978-04-13 1979-04-06 4-aza-17-substituted-5alpha-androstan-3-ones
EP79101131A EP0004949B1 (en) 1978-04-13 1979-04-12 4-aza-17-substituted-5-alpha-androstan-3-one, their a and d homo analogs, process for their preparation and pharmaceutical compositions containing them
CA000325640A CA1142914A (en) 1978-04-13 1979-04-12 4-AZA-17-SUBSTITUTED-5.alpha.-ANDROSTAN-3-ONES USEFUL AS 5.alpha.-REDUCTASE INHIBITORS
ZA791752A ZA791752B (en) 1978-04-13 1979-04-12 4-aza-17 beta -substituted-5 alpha -androstan-3-ones useful as 5 alpha -reductase inhibitors
KR1019790001163A KR830000085B1 (ko) 1978-04-13 1979-04-12 5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법
JP4445879A JPS54145669A (en) 1978-04-13 1979-04-13 44azaa177substitutedd5 alphaaandrostanee33one which is testosteronee5 alphaareductase repressor
IE765/79A IE48127B1 (en) 1978-04-13 1979-08-08 4-aza-17-substituted-5 -androstan-3-one,their a- and d- homo analogues,process for their preparation and pharmaceutical compositions containing them
US06/189,981 US4377584A (en) 1978-04-13 1980-09-23 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
JP62231223A JPS63152320A (ja) 1978-04-13 1987-09-17 ４−アザ−１７−置換−５α−アンドロスタン−３−オンを含むテストステロン−５α−レダクターゼ阻害剤組成物
HK801/87A HK80187A (en) 1978-04-13 1987-10-29 4-aza-17-substituted-5-alpha-androstan-3-one, their a and d homo analogs, process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89611878A 1978-04-13 1978-04-13
KR1019790001163A KR830000085B1 (ko) 1978-04-13 1979-04-12 5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법

Publications (1)

Publication Number Publication Date
KR830000085B1 true KR830000085B1 (ko) 1983-02-08

Family

ID=26626480

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019790001163A Expired KR830000085B1 (ko) 1978-04-13 1979-04-12 5α-환원효소 억제제로서 유용한 4-아자-17-치환-5α-안드로스탄-3-온류의 제조방법

Country Status (3)

Country Link
JP (2) JPS54145669A (enExample)
KR (1) KR830000085B1 (enExample)
ZA (1) ZA791752B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5669952A (en) * 1979-11-09 1981-06-11 Nec Corp Result report control system in message communication
ZA851426B (en) * 1984-02-27 1986-10-29 Merck & Co Inc 17 beta-n-monosubstituted carbamoyl-4-aza-5 alpha-androst-1-en-3-ones as 5 alpha reductase inhibitors
IL74365A (en) * 1984-02-27 1990-07-26 Merck & Co Inc 17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing it
US4888336A (en) * 1987-01-28 1989-12-19 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors
CA2084799C (en) * 1991-12-17 2003-01-28 Glenn J. Gormley Method of prevention of prostatic carcinoma with 17 beta-n-monosubstituted-carbamoyl-4-aza-5 alpha-androst-1 -en-3-ones
EP0547687A1 (en) * 1991-12-18 1993-06-23 Merck & Co. Inc. 17B-N-Substituted adamantyl/norbonanyl carbamoyl-4-aza-5a-and-rost-1-en-3-ones and androstan-3 ones

Also Published As

Publication number Publication date
ZA791752B (en) 1980-11-26
JPS54145669A (en) 1979-11-14
JPH0246566B2 (enExample) 1990-10-16
JPS6361315B2 (enExample) 1988-11-28
JPS63152320A (ja) 1988-06-24

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