KR790000589B1 - Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate - Google Patents

Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate

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Publication number
KR790000589B1
KR790000589B1 KR7803117A KR780003117A KR790000589B1 KR 790000589 B1 KR790000589 B1 KR 790000589B1 KR 7803117 A KR7803117 A KR 7803117A KR 780003117 A KR780003117 A KR 780003117A KR 790000589 B1 KR790000589 B1 KR 790000589B1
Authority
KR
South Korea
Prior art keywords
methylpregna
diene
dione17
dehydroxy
diacetate
Prior art date
Application number
KR7803117A
Other languages
Korean (ko)
Inventor
Emory Ayer D
L Flynn Gordon
Alvin Schlargel C
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to KR7803117A priority Critical patent/KR790000589B1/en
Application granted granted Critical
Publication of KR790000589B1 publication Critical patent/KR790000589B1/en

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Abstract

Title compd. (I), possessing anti-inflammatory activity, was prepd. from 6&, 9&-difluoro-11β, 17, 21-trihydroxy-16β-methylpregna-1,4-diene-3, 20-dione(II) in 3 steps. Thus, II was converted to compd. (III) and then to 6&, 9&-difluoro-11β, 17, 21-trihydroxy-16β-methylpregna-1,4-diene-3, 20-dione-17-acetate (IV). Intermediate IV was 21-acetylated by treating with anhydrous acetate in the presence of a base to give I.
KR7803117A 1978-10-14 1978-10-14 Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate KR790000589B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR7803117A KR790000589B1 (en) 1978-10-14 1978-10-14 Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR7803117A KR790000589B1 (en) 1978-10-14 1978-10-14 Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate

Publications (1)

Publication Number Publication Date
KR790000589B1 true KR790000589B1 (en) 1979-06-08

Family

ID=19208946

Family Applications (1)

Application Number Title Priority Date Filing Date
KR7803117A KR790000589B1 (en) 1978-10-14 1978-10-14 Method for producing 6l-fluoro-17,21-dehydroxy-16b-methylpregna-4,9(11)diene-3,20-dione17,21-diacetate

Country Status (1)

Country Link
KR (1) KR790000589B1 (en)

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