KR20250049461A - 전구단백질 컨버타제 서브틸리신 켁신(ｐｃｓｋ9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물 - Google Patents

전구단백질 컨버타제 서브틸리신 켁신(ｐｃｓｋ9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물 Download PDF

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KR20250049461A
KR20250049461A KR1020257010999A KR20257010999A KR20250049461A KR 20250049461 A KR20250049461 A KR 20250049461A KR 1020257010999 A KR1020257010999 A KR 1020257010999A KR 20257010999 A KR20257010999 A KR 20257010999A KR 20250049461 A KR20250049461 A KR 20250049461A
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nucleotides
double
antisense strand
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케빈 피츠제럴드
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알닐람 파마슈티칼스 인코포레이티드
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21061—Kexin (3.4.21.61), i.e. proprotein convertase subtilisin/kexin type 9
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020257010999A 2015-08-25 2016-08-25 전구단백질 컨버타제 서브틸리신 켁신(ｐｃｓｋ9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물 Pending KR20250049461A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562209526P 2015-08-25 2015-08-25
US62/209,526 2015-08-25
KR1020187008279A KR102793532B1 (ko) 2015-08-25 2016-08-25 전구단백질 컨버타제 서브틸리신 켁신 (pcsk9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물
PCT/US2016/048666 WO2017035340A1 (en) 2015-08-25 2016-08-25 Methods and compositions for treating a proprotein convertase subtilisin kexin (pcsk9) gene-associated disorder

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KR1020187008279A Division KR102793532B1 (ko) 2015-08-25 2016-08-25 전구단백질 컨버타제 서브틸리신 켁신 (pcsk9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물

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KR1020257010999A Pending KR20250049461A (ko) 2015-08-25 2016-08-25 전구단백질 컨버타제 서브틸리신 켁신(ｐｃｓｋ9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물
KR1020187008279A Active KR102793532B1 (ko) 2015-08-25 2016-08-25 전구단백질 컨버타제 서브틸리신 켁신 (pcsk9) 유전자-관련 장애를 치료하기 위한 방법 및 조성물

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US (6) US20180187198A1 (enExample)
EP (1) EP3340994A1 (enExample)
JP (3) JP6941598B2 (enExample)
KR (2) KR20250049461A (enExample)
CN (6) CN108348541A (enExample)
AU (3) AU2016310494B2 (enExample)
CA (1) CA2996701C (enExample)
EA (1) EA201890571A1 (enExample)
HK (1) HK1257523A1 (enExample)
IL (3) IL310959A (enExample)
MX (2) MX2018002158A (enExample)
WO (1) WO2017035340A1 (enExample)

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