KR20240122785A - 면역원성 조성물 및 이의 용도 - Google Patents

면역원성 조성물 및 이의 용도 Download PDF

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Publication number
KR20240122785A
KR20240122785A KR1020247020924A KR20247020924A KR20240122785A KR 20240122785 A KR20240122785 A KR 20240122785A KR 1020247020924 A KR1020247020924 A KR 1020247020924A KR 20247020924 A KR20247020924 A KR 20247020924A KR 20240122785 A KR20240122785 A KR 20240122785A
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Prior art keywords
immunogen
sequence
sequence encoding
circular polyribonucleotide
polyribonucleotide
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KR1020247020924A
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Korean (ko)
Inventor
제니퍼 에이. 넬슨
에릭 폴 카터
마이클 도나토 멜피
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플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨
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Publication of KR20240122785A publication Critical patent/KR20240122785A/ko
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/09—Recombinant DNA-technology
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
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    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020247020924A 2021-11-24 2022-11-23 면역원성 조성물 및 이의 용도 Pending KR20240122785A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163283029P 2021-11-24 2021-11-24
US63/283,029 2021-11-24
PCT/US2022/050908 WO2023097003A2 (en) 2021-11-24 2022-11-23 Immunogenic compositions and their uses

Publications (1)

Publication Number Publication Date
KR20240122785A true KR20240122785A (ko) 2024-08-13

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ID=84901161

Family Applications (1)

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KR1020247020924A Pending KR20240122785A (ko) 2021-11-24 2022-11-23 면역원성 조성물 및 이의 용도

Country Status (12)

Country Link
US (1) US20250032604A1 (https=)
EP (1) EP4436598A2 (https=)
JP (1) JP2024541465A (https=)
KR (1) KR20240122785A (https=)
CN (1) CN118555966A (https=)
AR (1) AR127764A1 (https=)
AU (1) AU2022397300A1 (https=)
CA (1) CA3238735A1 (https=)
IL (1) IL312965A (https=)
MX (1) MX2024006440A (https=)
TW (1) TW202330921A (https=)
WO (1) WO2023097003A2 (https=)

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WO2025227110A2 (en) * 2024-04-25 2025-10-30 Immorna Biotherapeutics Inc. Multivalent antigens

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