KR20240105468A - Rna 바이오마커 검출 방법 - Google Patents

Rna 바이오마커 검출 방법 Download PDF

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Publication number
KR20240105468A
KR20240105468A KR1020247020263A KR20247020263A KR20240105468A KR 20240105468 A KR20240105468 A KR 20240105468A KR 1020247020263 A KR1020247020263 A KR 1020247020263A KR 20247020263 A KR20247020263 A KR 20247020263A KR 20240105468 A KR20240105468 A KR 20240105468A
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KR
South Korea
Prior art keywords
cancer
tumor
rna
expression
itf3756
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Pending
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KR1020247020263A
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English (en)
Korean (ko)
Inventor
지안루카 포사티
키아라 리파몬티
크리스티앙 스테인퀼러
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이탈파마코 에스.피.에이.
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Application filed by 이탈파마코 에스.피.에이. filed Critical 이탈파마코 에스.피.에이.
Publication of KR20240105468A publication Critical patent/KR20240105468A/ko
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00Nucleic acid detection characterised by assay method
    • C12Q2561/101Taqman
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020247020263A 2021-11-23 2022-11-22 Rna 바이오마커 검출 방법 Pending KR20240105468A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT202100029558 2021-11-23
IT102021000029558 2021-11-23
PCT/EP2022/082762 WO2023094365A1 (en) 2021-11-23 2022-11-22 Method to detect rna biomarkers

Publications (1)

Publication Number Publication Date
KR20240105468A true KR20240105468A (ko) 2024-07-05

Family

ID=80121649

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247020263A Pending KR20240105468A (ko) 2021-11-23 2022-11-22 Rna 바이오마커 검출 방법

Country Status (9)

Country Link
US (1) US20250011878A1 (https=)
EP (1) EP4437138A1 (https=)
JP (1) JP2024543138A (https=)
KR (1) KR20240105468A (https=)
CN (1) CN118202068A (https=)
AR (1) AR127708A1 (https=)
CA (1) CA3235259A1 (https=)
TW (1) TW202340480A (https=)
WO (1) WO2023094365A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025080842A1 (en) * 2023-10-11 2025-04-17 Dana-Farber Cancer Institute, Inc. Methods of cancer detection, prediction of response to therapy, and treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012018499A2 (en) * 2010-08-05 2012-02-09 Acetylon Pharmaceuticals Specific regulation of cytokine levels by hdac6 inhibitors
US20120176076A1 (en) 2011-01-10 2012-07-12 Carl Mansfield Methods and systems for powering auxiliary devices in photovol taic system
WO2014032899A1 (en) * 2012-08-31 2014-03-06 Novo Nordisk A/S Diagnosis and treatment of lupus nephritis
EP3084446B1 (en) * 2013-12-20 2022-12-14 Acetylon Pharmaceuticals, Inc. Histone deacetylase 6 (hdac6) biomarkers in multiple myeloma
CA2995520A1 (en) * 2015-08-14 2017-02-23 Hendrik Jan VAN OOIJEN Assessment of nfkb cellular signaling pathway activity using mathematical modelling of target gene expression
WO2017070441A1 (en) * 2015-10-23 2017-04-27 Icahn School Of Medicine At Mount Sinai Identifying and treating cancer patients who are suitable for a targeted therapy using an hdac6 inhibitor
IT201700041723A1 (it) 2017-04-14 2018-10-14 Italfarmaco Spa Nuovi inibitori selettivi di HDAC6

Also Published As

Publication number Publication date
JP2024543138A (ja) 2024-11-19
CA3235259A1 (en) 2023-06-01
US20250011878A1 (en) 2025-01-09
WO2023094365A1 (en) 2023-06-01
TW202340480A (zh) 2023-10-16
CN118202068A (zh) 2024-06-14
EP4437138A1 (en) 2024-10-02
AR127708A1 (es) 2024-02-21

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20240618

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application