KR20240058358A - Cosmetic composition for improving skin condtion - Google Patents
Cosmetic composition for improving skin condtion Download PDFInfo
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- KR20240058358A KR20240058358A KR1020220139005A KR20220139005A KR20240058358A KR 20240058358 A KR20240058358 A KR 20240058358A KR 1020220139005 A KR1020220139005 A KR 1020220139005A KR 20220139005 A KR20220139005 A KR 20220139005A KR 20240058358 A KR20240058358 A KR 20240058358A
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- South Korea
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- cosmetic composition
- improving skin
- culture
- lotion
- skin condition
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
본 발명은 피부 상태 개선용 화장료 조성물에 관한 것으로, Lactobacillus, Lactococcus, Bifida 및 Leuconostoc 중 적어도 하나 이상의 배양물로 구성된 유산균 복합 배양물을 포함하여 이루어진다. The present invention relates to a cosmetic composition for improving skin condition, comprising a complex culture of lactic acid bacteria consisting of at least one culture of Lactobacillus, Lactococcus, Bifida, and Leuconostoc.
Description
본 발명은 피부 상태 개선용 화장료 조성물에 관한 것으로, 더욱 상세하게는 피부의 염증을 완화시키고 미백 효과를 제공하는, 피부 상태 개선용 화장료 조성물에 관한 것이다. The present invention relates to a cosmetic composition for improving skin condition, and more specifically, to a cosmetic composition for improving skin condition that relieves skin inflammation and provides a whitening effect.
사람의 피부색은 피부 내부의 멜라닌(melanin) 농도와 분포에 따라 결정되는데, 유전적인 요인 외에도, 태양 자외선이나 피로, 스트레스 등의 환경적 또는 생리적 조건에 의해서도 영향을 받는다. 멜라닌은 피부 표피층에 있는 멜라노사이트에서 합성되는데, 멜라노사이트 내 소기관인 멜라노좀(melanosome)에서 아미노산의 일종인 티로신(tyrosine)에 티로시나제(tyrosinase)라는 효소가 작용하여 도파(DOPA), 도파퀴논(dopaquinone)으로 바뀐 후 비효소적인 산화반응을 거쳐 만들어진다. 이와 같은 멜라닌의 합성이 피부 내에서 과도하게 일어나면, 피부 톤을 어둡게 하고, 기미, 주근깨 등을 발생시킨다. 따라서, 피부 내의 티로시나제 활성을 저해하여 멜라닌 색소의 합성을 저해시키면, 피부 톤을 밝게 하여 피부 미백을 실현할 수 있을 뿐만 아니라 자외선, 호르몬 및 유전적인 원인에 기인하여 발생하는 기미, 주근깨 등의 피부 과색소 침착증을 개선시킬 수 있다. 상기 피부의 미백을 위해 많은 합성물이 사용되고 있지만 미백 이외의 피부 붉어짐, 피부 염증 등과 같은 부작용이 발생하기도 한다. A person's skin color is determined by the concentration and distribution of melanin inside the skin. In addition to genetic factors, it is also affected by environmental or physiological conditions such as solar ultraviolet rays, fatigue, and stress. Melanin is synthesized in melanocytes in the epidermal layer of the skin. In melanosomes, an organelle within melanocytes, an enzyme called tyrosinase acts on tyrosine, a type of amino acid, to produce DOPA and dopaquinone. ) and then produced through a non-enzymatic oxidation reaction. If this synthesis of melanin occurs excessively within the skin, it darkens the skin tone and causes spots, freckles, etc. Therefore, by inhibiting the synthesis of melanin pigment by inhibiting the activity of tyrosinase in the skin, not only can skin whitening be achieved by brightening the skin tone, but also skin hyperpigmentation such as spots and freckles caused by ultraviolet rays, hormones, and genetic causes. It can improve calmness. Many synthetic compounds are used to whiten the skin, but side effects such as skin redness and skin inflammation other than whitening may occur.
피부에서의 염증반응(inflammatory response)은 물리적 자극이나 화학물질, 세균 등에 의해 피부손상이 유발될 때 이를 방어하기 위한 작용으로서 시작되며 다양한 면역세포와 염증성 사이토카인이 관여한다. IL-6(interleukin-6), IL-8(interleukin-8), IL-1β(interleukin-β) 등이 대표적인 염증 유도 사이토카인이다. IL-1β는 활성화된 단핵식균세포, 상피세포, 혈관내피세포에 의해 만들어져 염증 반응을 매개하는 전형적인 사이토카인이고, IL-6는 T 세포 및 대식세포에 의해 분비되어 면역 반응을 자극하며 염증 반응을 조절하는 사이토카인이다. 또한 활성화된 대식세포(macrophage)는 염증성 사이토카인뿐만 아니라 일산화질소(nitric oxide: NO)나 프로스타글란딘(prostagladin) E2 (PGE2)를 과도하게 생성하여 염증 과정을 더욱 활성화시킨다. 피부의 염증을 완하기 위해 많은 연구가 진행되고 있다.The inflammatory response in the skin begins as a defense function when skin damage is caused by physical stimulation, chemicals, bacteria, etc., and various immune cells and inflammatory cytokines are involved. Interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-β (IL-1β) are representative inflammation-inducing cytokines. IL-1β is a typical cytokine produced by activated mononuclear phagocytes, epithelial cells, and vascular endothelial cells and mediates inflammatory responses, while IL-6 is secreted by T cells and macrophages to stimulate immune responses and promote inflammatory responses. It is a cytokine that regulates Additionally, activated macrophages produce excessive amounts of nitric oxide (NO) and prostaglandin E2 (PGE2) as well as inflammatory cytokines, further activating the inflammatory process. A lot of research is being done to relieve skin inflammation.
많은 유산균을 이용한 발효물에서 피부의 미백 및 염증 개선을 위한 연구가 진행 중이다. 한국출원특허번호 제 10-2020-0040330호에는 블루베리 및 흑미 추출물의 유산균 발효물을 포함하는 미세먼지에 의한 피부 염증 예방 또는 개선용 화장료 조성물이 개시되어 있고, 한국출원번호 제 10-2021-0005762호에는 수박의 줄기 및 잎 추출물의 발효물을 유효성분으로 포함하는 항산화 또는 항염증용 화장료 조성물이 개시되어 있다. 이에 본 발명자들은 피부의 미백 및 염증 개선을 위해 연구한 결과, 유산균 복합 배양물이 피부의 미백및 염증에 효과 있는 것을 확인하고 본 발명을 완성하였다. Research is underway to improve skin whitening and inflammation using fermented products using many lactic acid bacteria. Korean Patent Application No. 10-2020-0040330 discloses a cosmetic composition for preventing or improving skin inflammation caused by fine dust containing lactic acid bacteria fermentation products of blueberry and black rice extract, and Korean Application No. 10-2021-0005762 Disclosed is an antioxidant or anti-inflammatory cosmetic composition containing fermented watermelon stem and leaf extract as an active ingredient. Accordingly, as a result of research on skin whitening and inflammation improvement, the present inventors confirmed that lactic acid bacteria complex culture is effective in skin whitening and inflammation, and completed the present invention.
본 발명은 상기와 같은 문제점을 해결하기 위해 안출된 것으로, 본 발명의 목적은 염증 유발 인자의 수준을 감소시켜 피부의 염증을 완화하고, 멜라닌의 생성량을 농도 의존적으로 감소시키고, 멜라닌 색소 형성에 관여하는 티로시나제의 생성을 억제하여 피부에 미백 효과를 제공하는, 피부 상태 개선용 화장료 조성물을 제공하고자 하는 것이다. The present invention was devised to solve the above problems. The purpose of the present invention is to alleviate skin inflammation by reducing the level of inflammation-causing factors, reduce the amount of melanin produced in a concentration-dependent manner, and participate in the formation of melanin pigment. The object is to provide a cosmetic composition for improving skin condition, which provides a whitening effect on the skin by inhibiting the production of tyrosinase.
본 발명의 해결과제는 이상에서 언급된 것들에 한정되지 않으며, 언급되지 아니한 다른 해결과제들은 아래의 기재로부터 당업자에게 명확하게 이해되어 질 수 있을 것이다.The problems to be solved by the present invention are not limited to those mentioned above, and other problems not mentioned can be clearly understood by those skilled in the art from the description below.
상기 목적을 달성하기 위한 본 발명에 의한 피부 상태 개선용 화장료 조성물은, Lactobacillus, Lactococcus, Bifida 및 Leuconostoc 중 적어도 하나 이상의 배양물로 구성된 유산균 복합 배양물을 포함한다. The cosmetic composition for improving skin condition according to the present invention for achieving the above object includes a complex culture of lactic acid bacteria composed of at least one culture of Lactobacillus, Lactococcus, Bifida, and Leuconostoc.
상기 유산균 복합 배양물은, Lactobacillus, Lactococcus, Bifida 및 Leuconostoc의 배양물을 5: 2: 1: 1 중량비로 혼합한 것이 바람직하다. The lactic acid bacteria complex culture is preferably a mixture of cultures of Lactobacillus, Lactococcus, Bifida and Leuconostoc in a weight ratio of 5: 2: 1: 1.
상기 Lactobacillus 배양물은, Soybean, Acerola Cherry 또는 Punica Granatum Fruit의 추출물을 이용하여 발효할 수 있다. The Lactobacillus culture can be fermented using extracts of Soybean, Acerola Cherry, or Punica Granatum Fruit.
상기 화장료 조성물은, 정제수를 42 내지 90 wt% 포함하고, 상기 유산균 복합 배양물을 10 내지 58 wt% 포함하는 것이 바람직하다. The cosmetic composition preferably contains 42 to 90 wt% of purified water and 10 to 58 wt% of the lactic acid bacteria complex culture.
상기 화장료 조성물은, 스킨로션, 스킨소프너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스쳐로션, 영양로션, 맛사지크림, 영양크림, 모이스쳐크림, 핸드크림, 파운데이션, 에센스, 영양에센스, 팩, 비누, 클렌징폼, 클렌징로션, 클렌징크림, 바디로션 및 바디클렌저로 구성된 그룹에서 선택된 하나 이상의 제형일 수 있다. The cosmetic composition includes skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, foundation, essence, nutritional essence, pack, soap, It may be one or more formulations selected from the group consisting of cleansing foam, cleansing lotion, cleansing cream, body lotion, and body cleanser.
상기 화장료 조성물은, 앰플 제형을 제외한 나머지 제형으로 이루어진 경우, 전체 조성물에 대하여 0.05 내지 100 wt%로 포함되는 것이 바람직하다. When the cosmetic composition consists of formulations other than the ampoule formulation, it is preferably contained in an amount of 0.05 to 100 wt% based on the total composition.
상기 화장료 조성물은, 프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 및 바실러스 배양물을 추가로 더 포함할 수 있다. The cosmetic composition may further include fructoolirosaccharide, bioecholia, aloe biome, and bacillus culture.
상기 프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 또는 바실러스 배양물은, 전체 조성물에 대하여 1 내지 10 wt% 포함될 수 있다. The fructoolirosaccharide, bioecholia, aloe biome, or bacillus culture may be included in an amount of 1 to 10 wt% based on the total composition.
상술한 바와 같은 구성을 가지는 본 발명에 의한 피부 상태 개선용 화장료 조성물은, 아토피 피부염 환자에서 황색포도상 구균에 대한 항균 활성을 보이며, 염증 유발 인자들의 수준을 감소시켜 피부의 염증을 완화하며, 멜라닌의 생성량을 농도 의존적으로 감소시키고, 멜라닌 색소 형성에 관여하는 티로시나제의 생성을 억제하여 피부의 색소 침착을 방지하면서 피부 미백을 가능하게 하는 효과가 있다. The cosmetic composition for improving skin condition according to the present invention having the above-described composition shows antibacterial activity against Staphylococcus aureus in patients with atopic dermatitis, relieves skin inflammation by reducing the level of inflammation-causing factors, and reduces the level of melanin. It has the effect of reducing the production amount in a concentration-dependent manner and suppressing the production of tyrosinase, which is involved in the formation of melanin pigment, preventing pigmentation of the skin and enabling skin whitening.
본 발명의 효과는 이상에서 언급된 것들에 한정되지 않으며, 언급되지 아니한 다른 효과들은 아래의 기재로부터 당업자에게 명확하게 이해되어 질 수 있을 것이다.The effects of the present invention are not limited to those mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the description below.
아하에서는 본 발명에 의한 피부 상태 개선용 화장료 조성물을 상세히 설명하기로 한다. In the following, the cosmetic composition for improving skin condition according to the present invention will be described in detail.
본 발명의 목적을 달성하기 위해, 본 발명은 유산균 복합 배양물을 포함하고, 피부 미백 및 염증 개선을 가능하게 하는 피부 상태 개선용 화장료 조성물을 제공할 수 있다.In order to achieve the object of the present invention, the present invention can provide a cosmetic composition for improving skin condition that includes a lactic acid bacteria complex culture and enables skin whitening and inflammation improvement.
상기 유산균 복합 배양물은 Lactobacillus, Lactococcus, Bifida 및 Leuconostoc의 배양물로 구성될 수 있다. The lactic acid bacteria complex culture may be composed of cultures of Lactobacillus, Lactococcus, Bifida, and Leuconostoc.
상기 Lactobacillus 및 Lactobacillus 균주는 아토피 피부염 환자에서 정상인과 비교하면 5배 비율로 검출되는 황색포도상 구균에 대한 항균 활성을 보인다. 또한 Lactobacillus는 염증을 유발하는 TNF-α 및 INF-γ의 분비량을 감소시켜 피부의 염증을 완하 하는 효과가 있다. Lactobacillus, 특히 Lactobacillus rhamnosus 시료를 농도별로 처리하고 24시간 후 멜라닌 생성량을 측정하면, 농도 의존적으로 감소하는 것을 확인하였으므로, 상기 유산균 복합체는 미백 효과가 있다. Bifida 및 Leuconostoc 배양물은 멜라닌 색소 형성에 관여하는 티로시나제(tyrosinase)의 생성을 억제하여 색소 침착을 막고, 미백 작용을 한다. The Lactobacillus and Lactobacillus strains show antibacterial activity against Staphylococcus aureus, which is detected at a rate of 5 times in patients with atopic dermatitis compared to normal people. Additionally, Lactobacillus has the effect of alleviating skin inflammation by reducing the secretion of TNF-α and INF-γ, which cause inflammation. When samples of Lactobacillus, especially Lactobacillus rhamnosus, were treated at different concentrations and melanin production was measured 24 hours later, it was confirmed that it decreased in a concentration-dependent manner, so the lactic acid bacteria complex has a whitening effect. Bifida and Leuconostoc cultures prevent pigmentation and have a whitening effect by inhibiting the production of tyrosinase, which is involved in the formation of melanin pigment.
상기 유산균 복합 배양물은 Lactobacillus, Lactococcus, Bifida 및 Leuconostoc의 배양물을 5: 2: 1: 1 중량비로 혼합한 것을 특징으로 할 수 있다. The lactic acid bacteria complex culture may be characterized by mixing cultures of Lactobacillus, Lactococcus, Bifida and Leuconostoc in a weight ratio of 5: 2: 1: 1.
상기 Lactobacillus 발효물은 Soybean, Acerola Cherry 또는 Punica Granatum Fruit의 추출물을 이용하여 발효한 것일 수 있다. The Lactobacillus fermented product may be fermented using extracts of Soybean, Acerola Cherry, or Punica Granatum Fruit.
상기 유산균 복합 배양물은 Lactobacillus/Soybean Ferment Extract, Lactobacillus Ferment, Lactococcus Ferment, Lactobacillus/Acerola Cherry Ferment, Bifida Ferment Filtrate, Lactobacillus/Punica Granatum Fruit Ferment Extract, Lactobacillus Ferment Lysate, Leuconostoc/Radish Root Ferment Filtrate 및 Lactococcus Ferment Lysate을 포함할 수 있으며, 상기 표기는 균주/배양액 구성을 기재한 것일 수 있다. The lactic acid bacteria complex culture includes Lactobacillus/Soybean Ferment Extract, Lactobacillus Ferment, Lactococcus Ferment, Lactobacillus/Acerola Cherry Ferment, Bifida Ferment Filtrate, Lactobacillus/Punica Granatum Fruit Ferment Extract, Lactobacillus Ferment Lysate, Leuconostoc/Radish Root Ferment Filtrate and Lactococcus Ferment Lysate. It may include, and the notation may describe the composition of the strain/culture medium.
상기 화장료 조성물은 정제수를 42 내지 90 wt% 포함하고, 상기 유산균 복합 배양물을 10 내지 58 wt% 포함하는 것을 특징으로 할 수 있다. The cosmetic composition may contain 42 to 90 wt% of purified water and 10 to 58 wt% of the lactic acid bacteria complex culture.
상기 유산균 복합 배양물은 항염증, 피부 장벽 강화, 미백, 피부 재생 및 항-노화 효과 있다. The lactic acid bacteria complex culture has anti-inflammatory, skin barrier strengthening, whitening, skin regeneration, and anti-aging effects.
피부용 화장품으로는 상기 화장료 조성물을 포함하는 스킨 및 바디 케어 화장품으로서 에센스, 앰플, 비누, 토닉 및 바디 에센스, 에멀젼, 로션, 크림(수중유적형, 유중수적형, 다중상), 용액, 현탁액(무수 및 수계), 무수 생성물(오일 및 글리콜계), 젤, 분말 등의 다양한 제형으로 제조될 수 있으며, 상기 화장료 조성물은 전체화장품에 대하여 0.05 내지 100 wt%로 포함되고, 앰플 제형의 경우 상기 기능성 조성물 100%로 이루어진 것일 수 있다.Cosmetics for skin include skin and body care cosmetics containing the above cosmetic composition, including essence, ampoule, soap, tonic and body essence, emulsion, lotion, cream (oil-in-water type, water-in-oil type, multi-phase), solution, and suspension (anhydrous). and water-based), anhydrous products (oil and glycol-based), gels, powders, etc., and the cosmetic composition is contained in an amount of 0.05 to 100 wt% based on the total cosmetics, and in the case of an ampoule formulation, the functional composition It may be made of 100%.
상기 화장료 조성물은 유산균 복합 배양물 이외에 피부 화장품 제제에 있어서 수용 가능한 담체를 포함할 수 있다. 상기 담체로서는 알콜, 오일, 계면활성제, 지방산, 실리콘 오일, 방부제, 습윤제, 보습제, 점성 변형제, 유제, 안정제, 자외선 차단제, 발색제, 향료, 희석제 등이 예시될 수 있다.The cosmetic composition may include a carrier acceptable for skin cosmetic preparations in addition to the lactic acid bacteria complex culture. Examples of the carrier include alcohol, oil, surfactant, fatty acid, silicone oil, preservative, wetting agent, moisturizing agent, viscosity modifier, emulsion, stabilizer, sunscreen, coloring agent, fragrance, diluent, etc.
상기 알코올, 오일, 계면활성제, 지방산, 실리콘 오일, 방부제, 습윤제, 보습제, 점성 변형제, 유제, 안정제, 자외선 차단제, 발색제, 향료, 희석제 등으로 사용될 수 있는 구체적인 화합물 또는 조성물은 이미 당업계에 공지되어 있기 때문에 당업자라면 적절한 해당 화합물 또는 조성물을 선택하여 사용할 수 있다. Specific compounds or compositions that can be used as the alcohol, oil, surfactant, fatty acid, silicone oil, preservative, wetting agent, moisturizer, viscosity modifier, emulsion, stabilizer, sunscreen, coloring agent, fragrance, diluent, etc. are already known in the art. Therefore, a person skilled in the art can select and use the appropriate compound or composition.
여기서 몇 가지를 예시하여 보면, 알콜로서는 고급 알콜, 프로필렌 글리콜, 1,3-부틸렌 글리콜, 글리세린, 소르비톨, 폴리에틸렌글리콜 등의 수용성 다가 알콜 등을 들 수 있고, 오일로서는 아보가드유, 팜유, 우지, 호호바유 등을 들 수 있고, 방부제로서는 에틸파라벤, 부틸파라벤 등을 들 수 있으며, 보습제로서는 히알론산, 황산콘드로이친(chondroitin sulfate), 피롤리돈카복실산염 등을 들 수 있으며, 희석제로서는 에탄올, 이소프로판올 등을 들 수 있다.To give a few examples, examples of alcohol include water-soluble polyhydric alcohols such as higher alcohols, propylene glycol, 1,3-butylene glycol, glycerin, sorbitol, and polyethylene glycol, and examples of oil include Avogard oil, palm oil, tallow, Examples include jojoba oil, etc., preservatives include ethylparaben, butylparaben, etc., moisturizers include hyaluronic acid, chondroitin sulfate, pyrrolidone carboxylate, etc., and diluents include ethanol, isopropanol, etc. can be mentioned.
더욱 구체적으로 피부용 화장품의 제형이 페이스트, 크림 또는 겔인 경우에는 담체 성분으로서 동물섬유, 식물섬유, 왁스, 파라핀, 전분, 트라칸트, 셀룰로오스 유도체, 폴리에틸렌 글리콜, 실리콘, 벤토나이트, 실리카, 탈크 또는 산화아연 등이 이용될 수 있다.More specifically, when the formulation of skin cosmetics is a paste, cream or gel, the carrier ingredients include animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide, etc. This can be used.
또한 제형이 파우더 또는 스프레이인 경우에는 담체 성분으로서 락토스, 탈크, 실리카, 알루미늄 히드록시드, 칼슘 실리케이트 또는 폴리아미드 파우더가 이용될 수 있고, 특히 스프레이인 경우에는 추가적으로 클로로플루오로히드로카본, 프로판/부탄 또는 디메틸 에테르와 같은 추진체를 포함할 수 있다.In addition, when the formulation is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as carrier ingredients, and especially when the formulation is a spray, chlorofluorohydrocarbon, propane/butane can be used as carrier ingredients. Alternatively, it may include a propellant such as dimethyl ether.
또한 제형이 용액 또는 유탁액의 경우에는 담체 성분으로서 용매, 용매화제 또는 유탁화제가 이용되고, 예컨대 물, 에탄올, 이소프로판올, 에틸 카보네이트, 에틸 아세테이트, 벤질 알코올, 벤질 벤조에이트, 프로필렌 글리콜, 1,3-부틸글리콜 오일, 글리세롤 지방족 에스테르, 폴리에틸렌 글리콜 또는 소르비탄의 지방산에스테르가 있다.Additionally, when the formulation is a solution or emulsion, a solvent, solvating agent, or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3 -There is butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid ester.
또한 제형이 현탁액인 경우에는 담체 성분으로서 물, 에탄올 또는 프로필렌 글리콜과 같은 액상 희석제, 에톡실화 이소스테아릴 알코올, 폴리옥시에틸렌 소르비톨 에스테르 및 폴리옥시에틸렌 소르비탄 에스테르와 같은 현탁제, 미소결정성 셀룰로오스, 알루미늄 메타히드록시드, 벤토나이트, 아가 또는 트라칸트 등이 이용될 수 있다.In addition, when the formulation is a suspension, the carrier ingredients include water, liquid diluents such as ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystalline cellulose, Aluminum metahydroxide, bentonite, agar or tracant, etc. can be used.
또한 제형이 계면-활성제 함유 클린징인 경우에는 담체 성분으로서 지방족 알코올 설페이트, 지방족 알코올 에테르 설페이트, 설포숙신산 모노에스테르, 이세티오네이트, 이미다졸리늄 유도체, 메틸타우레이트, 사르코시네이트, 지방산 아미드 에테르 설페이트, 알킬아미도베타인, 지방족 알코올, 지방산 글리세리드, 지방산 디에탄올아미드, 식물성 유, 리놀린 유도체 또는 에톡실화 글리세롤 지방산 에스테르 등이 이용될 수 있다.In addition, when the formulation is a cleansing agent containing a surfactant, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, and fatty acid amide ether sulfate. , alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, linoline derivative, or ethoxylated glycerol fatty acid ester can be used.
또한 본 발명의 일실시예에 따른 유산균 복합 배양물을 포함하는 비누의 경우, 비누 기재에 유산균 복합 배양물을 포함하여 제조될 수 있으며, 첨가제로서 피부 보습제, 유화제, 경수 연화제 등을 포함하여 제조될 수 있다.In addition, in the case of soap containing a lactic acid bacteria complex culture according to an embodiment of the present invention, it can be manufactured by including the lactic acid bacteria complex culture in the soap base, and can be manufactured by including a skin moisturizer, emulsifier, water softener, etc. as additives. You can.
상기 비누 기재로서는 야자유, 팜유, 대두유, 파마자유, 올리브유, 팜핵류 등의 식물유지 또는 우지, 돈지, 양지, 어유 등의 동물유지 등이 사용될 수 있고, 상기 피부 보습제로서는 글리세린, 에리트리톨, 폴리에틸렌글리콜, 프로필렌글리콜, 부틸렌글리콜, 펜틸렌글리콜, 헥실글리콜, 이소프로필미리스테이트, 실리콘 유도체, 알로에베라, 솔비톨 등이 사용될 수 있으며, 상기 유화제로서는 천연오일, 왁스 지방알콜, 탄화수소류, 천연식물 추출물 등이 사용될 수 있고, 상기 경수연화제로서는 테트라소듐 이디티에이 등이 사용될 수 있다.As the soap base, vegetable oil such as palm oil, palm oil, soybean oil, legume oil, olive oil, and palm kernels or animal oil such as tallow, pork fat, brisket, and fish oil can be used, and the skin moisturizer may include glycerin, erythritol, and polyethylene glycol. , propylene glycol, butylene glycol, pentylene glycol, hexyl glycol, isopropyl myristate, silicone derivatives, aloe vera, sorbitol, etc. can be used, and the emulsifiers include natural oils, waxy fatty alcohols, hydrocarbons, natural plant extracts, etc. may be used, and as the water softener, tetrasodium EDTA, etc. may be used.
본 발명의 비누 조성물은 또한 첨가제로서 항균제, 분산제, 거품억제제, 용매, 물때 방지제, 부식 방지제, 향료, 색소, 금속이온 봉쇄제, 산화방지제, 방부제 등을 추가적으로 포함할 수 있다.The soap composition of the present invention may additionally include additives such as antibacterial agents, dispersants, anti-foaming agents, solvents, anti-scaling agents, corrosion inhibitors, fragrances, pigments, metal ion sequestering agents, antioxidants, preservatives, etc.
본 발명의 일 구현 예에 따른 방법에 있어서, 상기 피부 상태 개선용 화장료 조성물은 프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 및 바실러스 배양물을 추가로 포함할 수 있다. In the method according to one embodiment of the present invention, the cosmetic composition for improving skin condition may further include fructo-olirosaccharide, bioecholia, aloe biome, and Bacillus culture.
프룩토올리로사카라이드(Fructooligosaccharides)는 유산균의 먹이로 활용되는 프리바이오틱스(Prebiotics)의 한 종류이다. 사람의 소화효소에 의해서 가수분해되지 않고, 장내 유익균에 의해서 이용된다. 사탕무 sugar beet의 효소반응으로, 이눌린 분해의 화학반응 또는 트랜스프룩토실레이션 과정으로 생성된 올리고사카라이드로, 주로 케토스, 니스토스, 프룩토실니스토스, 바일루코스, 이눌로바이오스, 이눌로트라이오스 및이눌로테트로오스로 구성되어 있다. 포도당에 과당이 2-4개 결합된 성분의 혼합물이다. 양파, 치커리 바난등의 천연 식푸멩 존재하는 성분이며, 안전성이 매우 높으며, 급성 독성 및 만성 독서등의 실험에서도 안정성이 확인되어 있다. 식품에도 사용되는 안전한 원료이므로, 피부에도 자극 없이 사용될 수 있다. Fructooligosaccharides are a type of prebiotics used as food for lactic acid bacteria. It is not hydrolyzed by human digestive enzymes and is used by beneficial intestinal bacteria. It is an oligosaccharide produced through the enzymatic reaction of sugar beet, the chemical reaction of inulin decomposition, or the transfructosylation process, mainly ketose, nystos, fructosylnystos, baylucose, inulobiose, and inulotriose. and inulotetrose. It is a mixture of 2-4 fructose bonds to glucose. It is an ingredient that exists in natural foods such as onions, chicory and banan, and its safety is very high, and its safety has been confirmed in tests such as acute toxicity and chronic reading. Since it is a safe raw material used in food, it can be used without irritating the skin.
바이오-에콜리아는 천연 물질를 발효시킨 것으로, 피부 표면의 유익균인 피부 상재균이 정상적으로 유지할 수 있도록 도와준다. 경쟁적 억제를 통해 Bio-Selective가 적용돼 유익균 성장으로 피부 면역력이 상승한다. 자세하게는 항균 펩타이드 생산을 촉진하며, 경쟁적 저해를 통한 유익균을 성장 시킨다. Bio-Echolia is a fermented natural substance that helps maintain normal skin flora, which are beneficial bacteria on the skin surface. Bio-Selective is applied through competitive inhibition, increasing skin immunity through the growth of beneficial bacteria. Specifically, it promotes the production of antibacterial peptides and grows beneficial bacteria through competitive inhibition.
알로에 바이옴은 알로에 베라 추출물에 락토바실러스균을 발효시킨 물질이다. 상기 알로에 바이옴은 멜라닌 색소 형성에 관여하는 티로시나제(tyrosinase)의 생성을 억제하여 색소 침착을 막고, 미백 작용을 하며, SOD(Super Oxide Dismutase)와 유사한 산화 억제 작용을 한다. 또한 보습을 개선하고 보습을 지속시키는 효과가 있다. 나아가 독성이 매우 낮아 화장료의 조성물로 사용하기 용이하며, 세포외 멜라닌 억제효과가 나타나 기미 및 주근깨의 발생을 억제하는 효과도 있다. Aloe biome is a substance made by fermenting Lactobacillus bacteria in aloe vera extract. The aloe biome prevents pigmentation by suppressing the production of tyrosinase, which is involved in the formation of melanin pigment, has a whitening effect, and has an oxidation inhibitory effect similar to SOD (Super Oxide Dismutase). It also has the effect of improving moisturization and maintaining moisturization. Furthermore, it has very low toxicity, making it easy to use as a cosmetic composition, and has an extracellular melanin suppression effect, which has the effect of suppressing the occurrence of spots and freckles.
바실러스 배양물은 글리세린 및 정제수를 이용하여 바실러스를 발효한 물질이다. 바실러스 배양물은 프로 콜라겐은 유도하여 피부 구조의 탄력을 증가시키고, 눈가 주름을 감소시키는 효과가 있다. 피부의 에너지를 증가시키고, 활성산소를 감소시키는 효과가 있다. Bacillus culture is a material obtained by fermenting Bacillus using glycerin and purified water. Bacillus culture has the effect of inducing procollagen, increasing the elasticity of the skin structure and reducing wrinkles around the eyes. It has the effect of increasing skin energy and reducing free radicals.
상기 프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 또는 바실러스 배양물은 전체 조성물에 대하여 1 내지 10 wt% 포함되는 것을 특징으로 할 수 있다. The fructoolirosaccharide, bioecholia, aloe biome, or bacillus culture may be included in an amount of 1 to 10 wt% based on the total composition.
이상, 본 발명에 대한 바람직한 실시예를 설명하였으나 본 발명은, 위에서 설명된 실시예들에 한정되지 않고 청구범위에 기재된 바에 의해 정의되며 본 발명이 속하는 기술분야에서 다양한 변형과 개발을 할 수 있음은 자명하다.Although the preferred embodiments of the present invention have been described above, the present invention is not limited to the embodiments described above, but is defined by the claims, and various modifications and developments can be made in the technical field to which the present invention pertains. Self-explanatory.
Claims (8)
A cosmetic composition for improving skin condition, comprising a complex culture of lactic acid bacteria consisting of at least one culture of Lactobacillus, Lactococcus, Bifida, and Leuconostoc.
상기 유산균 복합 배양물은,
Lactobacillus, Lactococcus, Bifida 및 Leuconostoc의 배양물을 5: 2: 1: 1 중량비로 혼합한 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to paragraph 1,
The lactic acid bacteria complex culture,
A cosmetic composition for improving skin condition, characterized in that cultures of Lactobacillus, Lactococcus, Bifida and Leuconostoc are mixed in a weight ratio of 5: 2: 1: 1.
상기 Lactobacillus 배양물은,
Soybean, Acerola Cherry 또는 Punica Granatum Fruit의 추출물을 이용하여 발효한 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to paragraph 1,
The Lactobacillus culture,
A cosmetic composition for improving skin condition, characterized by fermentation using extracts of Soybean, Acerola Cherry or Punica Granatum Fruit.
상기 화장료 조성물은,
정제수를 42 내지 90 wt% 포함하고, 상기 유산균 복합 배양물을 10 내지 58 wt% 포함하는 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to paragraph 1,
The cosmetic composition is,
A cosmetic composition for improving skin condition, comprising 42 to 90 wt% of purified water and 10 to 58 wt% of the lactic acid bacteria complex culture.
상기 화장료 조성물은,
스킨로션, 스킨소프너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스쳐로션, 영양로션, 맛사지크림, 영양크림, 모이스쳐크림, 핸드크림, 파운데이션, 에센스, 영양에센스, 팩, 비누, 클렌징폼, 클렌징로션, 클렌징크림, 바디로션 및 바디클렌저로 구성된 그룹에서 선택된 하나 이상의 제형인 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to paragraph 1,
The cosmetic composition is,
Skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, foundation, essence, nutritional essence, pack, soap, cleansing foam, cleansing lotion , A cosmetic composition for improving skin condition, characterized in that it is one or more formulations selected from the group consisting of cleansing cream, body lotion, and body cleanser.
상기 화장료 조성물은,
앰플 제형을 제외한 나머지 제형으로 이루어진 경우, 전체 조성물에 대하여 0.05 내지 100 wt%로 포함되는 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to clause 5,
The cosmetic composition is,
A cosmetic composition for improving skin condition, characterized in that it is contained in an amount of 0.05 to 100 wt% based on the total composition when composed of other formulations excluding the ampoule formulation.
상기 화장료 조성물은,
프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 및 바실러스 배양물을 추가로 더 포함하는 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.
According to paragraph 1,
The cosmetic composition is,
A cosmetic composition for improving skin condition, further comprising fructoolirosaccharide, bioecholia, aloe biome, and bacillus culture.
상기 프룩토올리로사카라이드, 바이오에콜리아, 알로에 바이옴 또는 바실러스 배양물은,
전체 조성물에 대하여 1 내지 10 wt% 포함되는 것을 특징으로 하는 피부 상태 개선용 화장료 조성물.In clause 7,
The fructoolirosaccharide, bioecholia, aloe biome or bacillus culture,
A cosmetic composition for improving skin condition, characterized in that it contains 1 to 10 wt% based on the total composition.
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