KR101028238B1 - A whitening cosmetic composition comprising birch, top and tall fortified extract - Google Patents

Abstract

The present invention relates to a whitening cosmetic composition comprising as an active ingredient a birch extract, an upper body extract, and a toughened extract. More particularly, the present invention relates to a whitening cosmetic composition comprising, as an active ingredient, 0.0001 to 10% by weight of a birch extract, 0.0001 to 10% by weight of a topical extract, and 0.0001 to 10% It shows a very low whitening effect and an improved whitening effect.

Birch, upper body, snow strengthen, whitening, cosmetics

Description

The present invention relates to a cosmetic composition containing Betula platyphylla var. japonica stem exract, Morus alba Linne ver. Morus bombycis Koidz stem extract and Galanthus nivalis whole plant extract}

  1 is a graph showing the effect of inhibiting tyrosinase activity using birch,

The present invention relates to a whitening cosmetic composition containing a natural plant extract. More particularly, the present invention relates to a whitening cosmetic composition comprising a birch extract, a topical extract,

Generally, when the skin is exposed to ultraviolet rays, the epidermis becomes black. This is due to the synthesis and release of melanin in melanocytes. Melanin is produced by tyrosine as a substrate in tyrosinase and tyrosinase as a result of enzymatic action to generate dopaquinone and spontaneous oxidation from dopaquinone.

Therefore, in order to prevent the skin from becoming black, the method of reducing the production of melanin by inhibiting some reactions during the melanin production is the simplest and general. For this purpose, various extracts such as hydroquinone, ascorbic acid, kojic acid, glutathione, mulberry bark extract, and arbutin have been conventionally used.

Among them, ascorbic acid, mucilage extract, glutathione and the like have been used to treat skin blackening or skin diseases, but their use has been limited due to problems in safety of skin and safety of cosmetic formulation. In addition, hydroquinone has been used as a medicine for the treatment of spots, but it has skin irritation, and ascorbic acid has difficulties in using because it has a problem of stability against light and heat, and high use cost.

In order to solve the above-mentioned problems, the present invention has found that skin stability is greatly improved while exhibiting a whitening effect synergistically when the ingredient ratio is appropriately adjusted using the birch extract, topical extract, It was completed.

The present invention provides a whitening cosmetic composition comprising, as an active ingredient, 0.0001 to 10% by weight of a birch extract, 0.0001 to 10% by weight of a topical extract, and 0.0001 to 10% by weight of a tallest fortified extract in a conventional cosmetic composition.

In the present invention, the birch extract, the topical extract, and the sea tangle extract, which are used as an active ingredient in the present invention, greatly reduce the skin irritation such as erythema and itching observed as side effects of the conventional whitening cosmetic composition, Respectively.

The birch extract, topical extract and tall skin-reinforced extract used as an active ingredient in the present invention may contain 0.0001 to 10% by weight of birch extract, 0.0001 to 10% by weight of topoisomeric extract and 0.0001 to 10% Preferably, the amount of the birch extract is 5 to 9% by weight, the amount of the upper body extract is 5 to 8% by weight, and the amount of the hardy extract is 4 to 8% by weight.

The extracts of birch extract, topoisomerase and tall oil-base extract of the present invention are each composed of 10% by weight on the dry weight basis.

When the content of birch is less than 5% by weight, synergistic effects can not be expected more. When the content of birch is more than 9% by weight, there is no significant effect due to increase of content, Is reduced. In the cosmetic composition of the present invention, a synergistic effect can not be expected when the content of the topical extract is less than 0.0001% by weight. When the content exceeds 8% by weight, there is no significant increase in the content of the topical extract, Lt; / RTI >

According to a most preferred embodiment of the present invention, the amount of the birch extract is 8 wt%, the amount of the top extract is 6 wt%, and the amount of the extract is 5 wt%.

In the cosmetic composition of the present invention, the birch extract and upper limb extract, which are used as active ingredients, are collectively referred to as substances extracted from the respective branches of birch and upper limb. In addition, In this case, the extraction method is not particularly limited, but a method of obtaining an extract by adding an aqueous or organic solvent to each of the birch stem, the mulberry stem and the tongue, specifically water, an anhydrous or a function having 1 to 4 carbon atoms It is preferable to use a method of obtaining an extract by adding a lower alcohol, acetone, ethyl acetate, butyl acetate, chloroform and 1, 3-butylene glycol, and other treatment methods using birch can also be used. It is obvious to those of ordinary skill in the art .

The components contained in the cosmetic composition of the present invention include components commonly used in cosmetic compositions in addition to birch extract, topical extract and tall oil-extracted extract as active ingredients, and examples thereof include antioxidants, stabilizers, solubilizers, vitamins, Customary adjuvants such as perfumes, and carriers.

The whitening composition of the present invention can be prepared in a conventional manner in the art and also in the form of a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing But are not limited to, cleansing, oils, powder foundations, emulsion foundations, wax foundations and sprays. More specifically, it can be manufactured in the form of a flexible lotion, a nutritional lotion, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder.

When the formulation of the present invention is a paste, a cream or a gel, an animal oil, a vegetable oil, a wax, a paraffin, a starch, a tracer, a cellulose derivative, polyethylene glycol, silicon, talc or zinc oxide may be used as a carrier component.

In the case where the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. Especially, in the case of spraying, chlorofluorohydrocarbons, Propane / butane or dimethyl ether.

When the formulation of the present invention is a solution or an emulsion, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

In the case where the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is an interfacial active agent-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention, and it is to be understood by those skilled in the art that the present invention is not limited thereto It will be obvious.

[Production Example] Preparation of cosmetic composition

Milk lotion compositions were prepared by referring to the ingredients and contents shown in Table 1 below. In the present invention, 100 g of each of the birch, upper and lower tillers was dipped in 900 ml of ethanol at 50 ° C for 5 hours, and then filtered and concentrated. 20g of each extract was obtained.

In the case of the examples, a certain amount of the natural plant extract of 8% by weight of the birch extract, 6% by weight of the upper body extract and 5% by weight of the lyophilized extract is effective in minimizing the side effects such as itching, Respectively.

Milk lotions of Example 1 and Comparative Examples 1 to 4 were prepared with the compositions shown in Table 1 below.

Milk lotion composition (unit: wt%) ingredient Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Birch extract 8 - 8 - - Upper limb extract 6 - - 6 - Strengthening extract 5 - - - 5 glycerin 5 5 5 5 5 Propylene glycol 4 4 4 4 4 Tocopheryl acetate 3 3 3 3 3 Liquid paraffin 4 4 4 4 4 Triethanolamine One One One One One Squalane 3 3 3 3 3 Macadamia nut oil 2 2 2 2 2 Polysorbate 60 1.5 1.5 1.5 1.5 1.5 Sorbitan sesquiterate 1.5 1.5 1.5 1.5 1.5 Propylparaben 0.5 0.5 0.5 0.5 0.5 Carboxyl vinyl polymer 1.5 1.5 1.5 1.5 1.5 incense a very small amount a very small amount a very small amount a very small amount a very small amount antiseptic a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance (% By weight) 100 100 100 100

Experimental Example 1: Skin Irritation Test

In order to examine the skin irritation of each cosmetic preparation prepared in the above Preparation Example, 20 healthy male adults and 20 female subjects were sprayed with 0.1 g of each sample in a 5 * 20 cm area for 2 hours and left for 1 hour After 24 hours, the change of skin condition was visually observed, and the stimulation rate was calculated as a criterion of satisfaction of Table 2 below.

Criteria for Satisfaction Determination value Degree of skin irritation -2 More reddened and bulging than around -One Our red flags One Slightly reddish than around 2 No erythema or unusual symptoms

The satisfaction of each subject was measured and divided by the number of subjects, and the average satisfaction was calculated and shown in Table 3 below.

Results of stimulation rate measurement Prescription Judgment result (after 1 hour) Judgment result (after 24 hours) Example 1 1.9 1.9 Comparative Example 1 1.8 1.8 Comparative Example 2 1.9 1.9 Comparative Example 3 1.8 1.9 Comparative Example 4 1.9 1.8

In the comparison of the above examples and the comparative examples, it was found that the skin irritation rate of the products according to the examples of the present invention was not significantly different from the comparative example.

Experimental Example 2: Measurement of whitening effect

The whitening effect of each of the 20 women aged 19 to 40 years with black skin was measured as follows. Six arms of the female subjects were marked with 1 cm widthwise and 1 cm length, and the cosmetic compositions of Example 1 and Comparative Examples 1 to 4 were respectively applied, and the remaining one was used as a control group. Then, the whitening degree (ΔL value) was measured at intervals of two weeks for one month using a measuring instrument, Minolta CR 300. The results are shown in Table 4 below.

Prescription Whitening degree Example 1 4.7 Comparative Example 1 0.6 Comparative Example 2 1.1 Comparative Example 3 1.5 Comparative Example 4 1.2 Control group 0

Experimental Example 3: Measurement of inhibitory effect of tyrosinase activity

The effect of inhibiting tyrosinase activity was measured by mixing the birch extract, topical extract and tall oil-extracted extract used in Example 1, and arbutin was used as a comparative substance.

First, add 1 ml of tyrosine to 0.3 mg / ml solution in distilled water, add 1 ml of potassium phosphate buffer solution (0.1 M, pH 6.8) and 1 ml of each solution (0.3, 0.6, 1.3, 2.5, 5.0, %, W / V)), and the mixture was incubated at 37 ° C in a thermostat for 10 minutes. As a control, only 0.9 ml of the solvent was added to each sample. 0.1 ml of tyrosinase solution of 2500 Unit / ml was added to the reaction solution, and the mixture was reacted in a 37 ° C thermostat for 10 minutes.

The reaction tube was quenched by placing it in ice water, and the absorbance at 475 nm was measured by a photoelectric spectrometer. The results are shown in FIG.

As shown in Fig. 1, it was confirmed that the mixture of birch extract, topical extract and tall fortified extract was proportionally increased in inhibition of tyrosinase activity depending on the concentration, and thus the whitening effect was excellent.

As described above, the present invention relates to a whitening cosmetic composition comprising the birch extract, the upper limb extract and the toughened extract as an active ingredient. The cosmetic composition of the present invention provides an improved whitening effect with very low skin irritation.

Claims (3)

A whitening cosmetic composition comprising 0.0001 to 10% by weight of a birch extract, 0.0001 to 10% by weight of a topical extract, and 0.0001 to 10% The method according to claim 1, The production of the birch extract, the upper and lower body extracts and the stout fortified extract is used in an amount of 10% by weight (w / w) based on ethanol as an extracting solvent with respect to the dry weight of the birch trunks, Composition The cosmetic composition according to claim 1, wherein the whitening cosmetic composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation and spray Wherein the cosmetic composition has a formulation selected from the group consisting of

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