KR20240009964A - 결절성 양진 치료를 위한 jak1 경로 억제제 - Google Patents
결절성 양진 치료를 위한 jak1 경로 억제제 Download PDFInfo
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- KR20240009964A KR20240009964A KR1020237041700A KR20237041700A KR20240009964A KR 20240009964 A KR20240009964 A KR 20240009964A KR 1020237041700 A KR1020237041700 A KR 1020237041700A KR 20237041700 A KR20237041700 A KR 20237041700A KR 20240009964 A KR20240009964 A KR 20240009964A
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- jak1
- pharmaceutically acceptable
- pathway inhibitor
- compound
- acceptable salt
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- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/247—IL-4
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US202163183249P | 2021-05-03 | 2021-05-03 | |
| US63/183,249 | 2021-05-03 | ||
| PCT/US2022/027389 WO2022235613A1 (en) | 2021-05-03 | 2022-05-03 | Jak1 pathway inhibitors for the treatment of prurigo nodularis |
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| KR20240009964A true KR20240009964A (ko) | 2024-01-23 |
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| AU2021396231A1 (en) | 2020-12-08 | 2023-06-22 | Incyte Corporation | Jak1 pathway inhibitors for the treatment of vitiligo |
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| CA2413330A1 (en) | 2000-06-28 | 2002-01-03 | Smithkline Beecham P.L.C. | Wet milling process |
| CA2762174C (en) | 2009-05-22 | 2018-02-20 | Incyte Corporation | N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| TW201113285A (en) | 2009-09-01 | 2011-04-16 | Incyte Corp | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| RS60680B1 (sr) | 2010-03-10 | 2020-09-30 | Incyte Holdings Corp | Piperidin-4-il azetidin derivati kao inhibitori jak1 |
| EP2640725B1 (en) | 2010-11-19 | 2015-01-07 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors |
| TW201249845A (en) | 2010-11-19 | 2012-12-16 | Incyte Corp | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
| MY165963A (en) | 2011-06-20 | 2018-05-18 | Incyte Holdings Corp | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors |
| TW201313721A (zh) | 2011-08-18 | 2013-04-01 | Incyte Corp | 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物 |
| AR091079A1 (es) | 2012-05-18 | 2014-12-30 | Incyte Corp | Derivados de pirrolopirimidina y pirrolopiridina sustituida con piperidinilciclobutilo como inhibidores de jak |
| US9181271B2 (en) | 2012-11-01 | 2015-11-10 | Incyte Holdings Corporation | Tricyclic fused thiophene derivatives as JAK inhibitors |
| PT3231801T (pt) | 2013-05-17 | 2019-05-24 | Incyte Corp | Sal de bipirazole como inibidor da jak |
| AU2014339897A1 (en) * | 2013-10-24 | 2016-04-21 | Abbvie Inc. | JAK1 selective inhibitor and uses thereof |
| TW201705961A (zh) * | 2015-06-11 | 2017-02-16 | 阿爾米雷爾有限公司 | 作為ｊａｋ抑制劑的２－（吡唑并吡啶－３－基）嘧啶衍生物 |
| MA49570A (fr) * | 2017-08-01 | 2020-05-20 | Theravance Biopharma R&D Ip Llc | Composés bicycliques pyrazolo et triazolo utilisés en tant qu'inhibiteurs de kinase jak |
| IL311485A (en) * | 2018-02-16 | 2024-05-01 | Incyte Corp | JAK1 pathway inhibitors for the treatment of cytokine-related disorders |
| TW202106681A (zh) * | 2019-04-24 | 2021-02-16 | 美商施萬生物製藥研發Ｉｐ有限責任公司 | 用於治療皮膚疾病之嘧啶jak抑制劑 |
| WO2021076124A1 (en) * | 2019-10-16 | 2021-04-22 | Incyte Corporation | Use of jak1 inhibitors for the treatment of cutaneous lupus erythematosus and lichen planus (lp) |
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| US20220378746A1 (en) | 2022-12-01 |
| TW202308610A (zh) | 2023-03-01 |
| WO2022235613A1 (en) | 2022-11-10 |
| CL2023003237A1 (es) | 2024-05-31 |
| EP4333840A1 (en) | 2024-03-13 |
| CA3219092A1 (en) | 2022-11-10 |
| CN117693339A (zh) | 2024-03-12 |
| IL308216A (en) | 2024-01-01 |
| AU2022270072A1 (en) | 2023-11-02 |
| JP2024516302A (ja) | 2024-04-12 |
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