KR20230169981A - 적혈구증가증을 치료하기 위한 조성물 및 방법 - Google Patents

적혈구증가증을 치료하기 위한 조성물 및 방법 Download PDF

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Publication number
KR20230169981A
KR20230169981A KR1020237034671A KR20237034671A KR20230169981A KR 20230169981 A KR20230169981 A KR 20230169981A KR 1020237034671 A KR1020237034671 A KR 1020237034671A KR 20237034671 A KR20237034671 A KR 20237034671A KR 20230169981 A KR20230169981 A KR 20230169981A
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KR
South Korea
Prior art keywords
subject
polycythemia
alkyl
group
glyt1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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KR1020237034671A
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English (en)
Korean (ko)
Inventor
존 퀴셀
윌리엄 자콥 새비지
마리아 가브리엘라 비코니
부 홍
민 우
이 시앙
파반 레디
Original Assignee
디스크 메디슨, 인크.
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Application filed by 디스크 메디슨, 인크. filed Critical 디스크 메디슨, 인크.
Publication of KR20230169981A publication Critical patent/KR20230169981A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020237034671A 2021-03-12 2022-03-11 적혈구증가증을 치료하기 위한 조성물 및 방법 Pending KR20230169981A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163160412P 2021-03-12 2021-03-12
US63/160,412 2021-03-12
US202163185464P 2021-05-07 2021-05-07
US63/185,464 2021-05-07
PCT/US2022/020038 WO2022192730A1 (en) 2021-03-12 2022-03-11 Compositions and methods for treating polycythemia

Publications (1)

Publication Number Publication Date
KR20230169981A true KR20230169981A (ko) 2023-12-18

Family

ID=83228388

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237034671A Pending KR20230169981A (ko) 2021-03-12 2022-03-11 적혈구증가증을 치료하기 위한 조성물 및 방법

Country Status (10)

Country Link
US (3) US20260027107A1 (https=)
EP (1) EP4304596A4 (https=)
JP (1) JP2024509265A (https=)
KR (1) KR20230169981A (https=)
AU (1) AU2022233178A1 (https=)
BR (1) BR112023018403A2 (https=)
CA (1) CA3213395A1 (https=)
IL (1) IL305806A (https=)
MX (1) MX2023010449A (https=)
WO (1) WO2022192730A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법
CN116942668A (zh) * 2023-03-17 2023-10-27 天津医科大学 Glyt1抑制剂在治疗器官纤维化中的应用
AU2024339974A1 (en) * 2023-09-15 2026-03-26 Disc Medicine, Inc. Glyt-1 inhibitors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20180036A1 (ar) * 2017-04-18 2019-01-30 Vifor Int Ag أملاح لمثبطات فروبورتين جديدة
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법

Also Published As

Publication number Publication date
US20240269132A1 (en) 2024-08-15
US20260027107A1 (en) 2026-01-29
US20250248995A1 (en) 2025-08-07
MX2023010449A (es) 2023-11-09
WO2022192730A1 (en) 2022-09-15
JP2024509265A (ja) 2024-02-29
EP4304596A1 (en) 2024-01-17
CA3213395A1 (en) 2022-09-15
IL305806A (en) 2023-11-01
AU2022233178A1 (en) 2023-10-26
EP4304596A4 (en) 2025-02-19
BR112023018403A2 (pt) 2023-10-10

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PA0105 International application

Patent event date: 20231011

Patent event code: PA01051R01D

Comment text: International Patent Application

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A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250221

Comment text: Request for Examination of Application