CA3213395A1 - Compositions and methods for treating polycythemia - Google Patents

Compositions and methods for treating polycythemia Download PDF

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Publication number
CA3213395A1
CA3213395A1 CA3213395A CA3213395A CA3213395A1 CA 3213395 A1 CA3213395 A1 CA 3213395A1 CA 3213395 A CA3213395 A CA 3213395A CA 3213395 A CA3213395 A CA 3213395A CA 3213395 A1 CA3213395 A1 CA 3213395A1
Authority
CA
Canada
Prior art keywords
subject
polycythemia
group
inhibitor
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3213395A
Other languages
English (en)
French (fr)
Inventor
John QUISEL
William Jacob Savage
Maria Gabriela Beconi
Vu HONG
Min Wu
Yi XIANG
Pavan REDDY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Disc Medicine Inc
Original Assignee
Disc Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Disc Medicine Inc filed Critical Disc Medicine Inc
Publication of CA3213395A1 publication Critical patent/CA3213395A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3213395A 2021-03-12 2022-03-11 Compositions and methods for treating polycythemia Pending CA3213395A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163160412P 2021-03-12 2021-03-12
US63/160,412 2021-03-12
US202163185464P 2021-05-07 2021-05-07
US63/185,464 2021-05-07
PCT/US2022/020038 WO2022192730A1 (en) 2021-03-12 2022-03-11 Compositions and methods for treating polycythemia

Publications (1)

Publication Number Publication Date
CA3213395A1 true CA3213395A1 (en) 2022-09-15

Family

ID=83228388

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3213395A Pending CA3213395A1 (en) 2021-03-12 2022-03-11 Compositions and methods for treating polycythemia

Country Status (10)

Country Link
US (3) US20260027107A1 (https=)
EP (1) EP4304596A4 (https=)
JP (1) JP2024509265A (https=)
KR (1) KR20230169981A (https=)
AU (1) AU2022233178A1 (https=)
BR (1) BR112023018403A2 (https=)
CA (1) CA3213395A1 (https=)
IL (1) IL305806A (https=)
MX (1) MX2023010449A (https=)
WO (1) WO2022192730A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법
CN116942668A (zh) * 2023-03-17 2023-10-27 天津医科大学 Glyt1抑制剂在治疗器官纤维化中的应用
AU2024339974A1 (en) * 2023-09-15 2026-03-26 Disc Medicine, Inc. Glyt-1 inhibitors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20180036A1 (ar) * 2017-04-18 2019-01-30 Vifor Int Ag أملاح لمثبطات فروبورتين جديدة
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법

Also Published As

Publication number Publication date
US20240269132A1 (en) 2024-08-15
US20260027107A1 (en) 2026-01-29
US20250248995A1 (en) 2025-08-07
MX2023010449A (es) 2023-11-09
WO2022192730A1 (en) 2022-09-15
KR20230169981A (ko) 2023-12-18
JP2024509265A (ja) 2024-02-29
EP4304596A1 (en) 2024-01-17
IL305806A (en) 2023-11-01
AU2022233178A1 (en) 2023-10-26
EP4304596A4 (en) 2025-02-19
BR112023018403A2 (pt) 2023-10-10

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