KR20230150834A - Ap-1 전사 인자를 인코딩하는 코돈-최적화된 뉴클레오티드 서열 - Google Patents

Ap-1 전사 인자를 인코딩하는 코돈-최적화된 뉴클레오티드 서열 Download PDF

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KR20230150834A
KR20230150834A KR1020237032290A KR20237032290A KR20230150834A KR 20230150834 A KR20230150834 A KR 20230150834A KR 1020237032290 A KR1020237032290 A KR 1020237032290A KR 20237032290 A KR20237032290 A KR 20237032290A KR 20230150834 A KR20230150834 A KR 20230150834A
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leu
ser
polynucleotide
pro
gly
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스펜서 박
퀴니 봉
블라이드 새더
병 류
마르크 라주아
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라이엘 이뮤노파마, 인크.
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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KR1020237032290A 2021-02-25 2022-02-24 Ap-1 전사 인자를 인코딩하는 코돈-최적화된 뉴클레오티드 서열 Pending KR20230150834A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163153879P 2021-02-25 2021-02-25
US63/153,879 2021-02-25
US202163263231P 2021-10-28 2021-10-28
US63/263,231 2021-10-28
US202263309380P 2022-02-11 2022-02-11
US63/309,380 2022-02-11
PCT/US2022/017733 WO2022182890A1 (en) 2021-02-25 2022-02-24 Codon-optimized nucleotide sequences encoding an ap-1 transcription factor

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KR20230150834A true KR20230150834A (ko) 2023-10-31

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KR1020237032290A Pending KR20230150834A (ko) 2021-02-25 2022-02-24 Ap-1 전사 인자를 인코딩하는 코돈-최적화된 뉴클레오티드 서열

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US (2) US12270032B2 (https=)
EP (1) EP4298230A1 (https=)
JP (1) JP2024510900A (https=)
KR (1) KR20230150834A (https=)
AU (1) AU2022226655A1 (https=)
CA (1) CA3174248A1 (https=)
WO (1) WO2022182890A1 (https=)

Families Citing this family (7)

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WO2021189008A1 (en) 2020-03-20 2021-09-23 Lyell Immunopharma, Inc. Novel recombinant cell surface markers
US12144827B2 (en) 2021-02-25 2024-11-19 Lyell Immunopharma, Inc. ROR1 targeting chimeric antigen receptor
EP4298230A1 (en) 2021-02-25 2024-01-03 Lyell Immunopharma, Inc. Codon-optimized nucleotide sequences encoding an ap-1 transcription factor
WO2025089255A1 (ja) * 2023-10-23 2025-05-01 慶應義塾 長期生存型ｔ細胞、医薬組成物、及び使用方法
WO2025131119A1 (en) * 2023-12-22 2025-06-26 Everest Medicines (China) Co., Ltd. Cancer vaccines and uses thereof
WO2025184170A1 (en) * 2024-02-27 2025-09-04 Overt Bio, Inc. Methods and compositions for improving t cell function in an immunosuppressive environment
WO2025199252A1 (en) * 2024-03-19 2025-09-25 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Inducible transcription factor expression for modulating immune cell function

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US20220307039A1 (en) 2022-09-29
US12270032B2 (en) 2025-04-08
EP4298230A1 (en) 2024-01-03
JP2024510900A (ja) 2024-03-12
CA3174248A1 (en) 2022-09-01
AU2022226655A9 (en) 2025-01-30
AU2022226655A1 (en) 2023-07-27
US20250297268A1 (en) 2025-09-25
WO2022182890A1 (en) 2022-09-01

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