KR20230136773A - Beverage composition for dementia prevention - Google Patents

Beverage composition for dementia prevention Download PDF

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KR20230136773A
KR20230136773A KR1020220033183A KR20220033183A KR20230136773A KR 20230136773 A KR20230136773 A KR 20230136773A KR 1020220033183 A KR1020220033183 A KR 1020220033183A KR 20220033183 A KR20220033183 A KR 20220033183A KR 20230136773 A KR20230136773 A KR 20230136773A
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extract
beverage composition
dementia
present
root extract
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이종윤
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이종윤
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14—Yeasts or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/15—Inorganic Compounds
    • A23V2250/156—Mineral combination
    • A23V2250/1642—Zinc
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/208—Fungi extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/21—Plant extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/21—Plant extracts
    • A23V2250/2122—Gingko Biloba
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/70—Vitamins
    • A23V2250/708—Vitamin C
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/14—Extraction

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  • Life Sciences & Earth Sciences (AREA)
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  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
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  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
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Abstract

본 발명은 치매예방용 음료조성물에 관한 것으로, 더욱 상세하게는 다양한 유효성분을 혼합하여 치매 증세 경감과 예방에 도움이 되며, 음료를 장기 복용해도 질리지 않을 맛을 제공하고, 당뇨환자가 장기 복용해도 당 수치를 올리지 않을 감미재를 첨가함으로써, 치매에 걸리지 않은 일반 대중들이나 당뇨를 가진 사람들도 수시로 음용할 수 있는 치매예방용 음료조성물에 관한 것이다.
또한, 본 발명은 브로컬리 추출물, 원지 추출물, 석창포 추출물, 흑생강 추출물, 참당귀 뿌리 추출물, 동충하초 추출물, 은행 잎 추출물, 용안육 및 유산균으로 이루어지는 기본 재료와; 비타민 C, 아연으로 이루어지는 활성화 재료;를 포함하는 것을 특징으로 한다.The present invention relates to a beverage composition for preventing dementia, and more specifically, to a beverage composition for preventing dementia, which helps alleviate and prevent dementia symptoms by mixing various active ingredients, provides a taste that will not be boring even if the drink is taken for a long period of time, and can be used even by diabetic patients for a long time. The present invention relates to a beverage composition for preventing dementia that can be consumed frequently by the general public without dementia or by people with diabetes, by adding a sweetener that does not raise sugar levels.
In addition, the present invention provides a basic material consisting of broccoli extract, root extract, Aspergillus root extract, black ginger extract, Angelica root extract, Cordyceps sinensis extract, ginkgo leaf extract, longan meat and lactic acid bacteria; It is characterized in that it contains an activating material consisting of vitamin C and zinc.

Description

치매예방용 음료조성물{Beverage composition for dementia prevention}Beverage composition for dementia prevention}

본 발명은 치매예방용 음료조성물에 관한 것으로, 더욱 상세하게는 다양한 유효성분을 혼합하여 치매 증세 경감과 예방에 도움이 되며, 음료를 장기 복용해도 질리지 않을 맛을 제공하고, 당뇨환자가 장기 복용해도 당 수치를 올리지 않을 감미재를 첨가함으로써, 치매에 걸리지 않은 일반 대중들이나 당뇨를 가진 사람들도 수시로 음용할 수 있는 치매예방용 음료조성물에 관한 것이다.The present invention relates to a beverage composition for preventing dementia, and more specifically, to a beverage composition for preventing dementia, which helps alleviate and prevent dementia symptoms by mixing various active ingredients, provides a taste that will not be boring even if the drink is taken for a long period of time, and can be used even by diabetic patients for a long time. The present invention relates to a beverage composition for preventing dementia that can be consumed frequently by the general public without dementia or by people with diabetes, by adding a sweetener that does not raise sugar levels.

치매는 다양한 유전적, 환경적 위험요소에 의해서 유발되는 다각적인 병인(multifaceted pathoge nesis)를 보이는 후천성 뇌질환으로 다발성 인지장애(multiple cognitive deficits)를 겪는 임상질환을 일컫는다. 가장 대표적인 치매원인 질환은 알츠하이머병으로 노년층에서 주로 발병하고 전체 치매의 60-70% 정도를 차지하는 것으로 보고되고 있다(Ann Neurol. 1993 May;33(5):494-501.).Dementia is an acquired brain disease with a multifaceted pathogenesis caused by various genetic and environmental risk factors and refers to a clinical disease suffering from multiple cognitive deficits. The most representative cause of dementia is Alzheimer's disease, which is reported to mainly occur in the elderly and account for 60-70% of all dementia (Ann Neurol. 1993 May;33(5):494-501.).

유전성과 산발성 알츠하이머병의 공통된 원인으로 알려져 있는 아밀로이드 베타단백질(Aβ)에 대한 연구가 활발히 진행되고 있다. Aβ는 정상인의 경우에도 인체 곳곳에서 소량 만들어진다. 정상인의 경우 Aβ는 만들어진 후 빠르게 분해돼 인체 내에 쌓이지 않지만 알츠하이머병 환자의 경우에는 Aβ가 비정상적으로 많이 생성되어 분해되지 않고 조직에 축적됨으로써 노인반이 생성되거나 기억과 학습에 중요한 역할을 하는 해마나 대뇌 피질 같은 곳에 과다하게 쌓이게 된다. 축적된 Aβ는 주변의 세포들에 염증 반응을 일으킨다. 따라서 신경 세포가 손상되고 점점 뇌의 정상적인 기능을 유지하는 신경 회로망마저 훼손되기에 이른다. 게다가 축적된 Aβ는 신경 세포를 죽이는 신호 체계를 가동 시키는 활성산소를 많이 만들어낸다.Research on amyloid beta protein (Aβ), which is known to be a common cause of hereditary and sporadic Alzheimer's disease, is actively underway. Even in normal people, Aβ is produced in small amounts throughout the body. In normal people, Aβ is quickly decomposed after it is created and does not accumulate in the body, but in patients with Alzheimer's disease, Aβ is produced in abnormally large amounts and accumulates in tissues without being decomposed, resulting in the formation of senile plaques or the hippocampus and cerebral cortex, which play an important role in memory and learning. Excessive amounts accumulate in the same place. Accumulated Aβ causes an inflammatory response in surrounding cells. Therefore, nerve cells are damaged and even the neural network that maintains the normal function of the brain is gradually damaged. In addition, accumulated Aβ generates a lot of reactive oxygen species, which activates a signaling system that kills nerve cells.

Aβ는 β-secretase에 의해 절단된 아밀로이드 전구단백질(amyloid precursor protein)의 일부분이다. Aβ는 그것을 구성하고 있는 아미노산의 수에 따라 여러 가지 형태가 있다. 알츠하이머병 환자의 경우 40개 또는 42개의 아미노산으로 이뤄진 Aβ의 비율이 급격히 많아진다. Aβ를 in vitro에서 배양하는 신경세포에 처리하였을 때 신경세포사를 유도하며 그 세포사의 기전이 알츠하이머병 환자에서 나타나는 apoptosis의 유형과 유사하다는 많은 보고들이 있다. Aβ1-42 또는 Aβ1-43 단백질에 의한 신경세포의 손상이 Alzheimer형 질환 유발의 중요한 원인중의 하나로 확인되고 있으며(Yan, S D et al. Nature 1997 Oct 16;389(6652):689-95.)(Haass C, Selkoe DJ. Cell 1993 Dec 17;75(6):1039-42.), Aβ25-35는 신경세포의 손상을 유발하는 Aβ1-42 or 43의 중요한 toxic fragment로서 알려지고 있다.(Pike CJ, Ramezan-Arab N, Cotman CW. J Neurochem 1997 Oct;69(4):1601-11.)(Lorenzo A, Yankner BA. Ann NY Acad Sci 777, 89-95, 1996.)Aβ is a part of amyloid precursor protein cleaved by β-secretase. Aβ has several forms depending on the number of amino acids that make it up. In patients with Alzheimer's disease, the proportion of Aβ, which consists of 40 or 42 amino acids, rapidly increases. There are many reports that Aβ induces neuronal cell death when treated with neuronal cells cultured in vitro, and that the cell death mechanism is similar to the type of apoptosis that occurs in Alzheimer's disease patients. Damage to nerve cells caused by Aβ1-42 or Aβ1-43 protein has been confirmed as one of the important causes of Alzheimer's disease (Yan, SD et al. Nature 1997 Oct 16;389(6652):689-95.) (Haass C, Selkoe DJ. Cell 1993 Dec 17;75(6):1039-42.), Aβ25-35 is known to be an important toxic fragment of Aβ1-42 or 43 that causes damage to nerve cells. (Pike CJ, Ramezan-Arab N, Cotman CW. J Neurochem 1997 Oct;69(4):1601-11.) (Lorenzo A, Yankner BA. Ann NY Acad Sci 777, 89-95, 1996.)

현재 FDA 승인을 받고 치매 치료를 위해 사용되고 있는 가장 보편적인 약물들에는 AChEI와 NMDA 수용체 길항제(N-Methyl-D-aspartate receptor antagonist)가 있으며, 이외에도 항산화제(antioxidant), 비스테로이드 항염증제(nonsteroidal anti-inflammatory drug, NSAID), 항염증제(anti-inflammatory agent), 스타틴(statin) 제제, 호르몬(hormone) 제제 등 다양한 약제들이 이들과 함께 혼용되어 사용되고 있다. The most common drugs currently approved by the FDA and used to treat dementia include AChEIs and NMDA receptor antagonists (N-Methyl-D-aspartate receptor antagonists), as well as antioxidants and nonsteroidal anti-inflammatory drugs. Various drugs, such as inflammatory drugs (NSAIDs), anti-inflammatory agents, statins, and hormones, are used interchangeably.

그러나 시중에는 알츠하이머 증세를 저감시키거나, 혈류를 개선하는 데 도움을 줄 수 있는 치매 예방을 위한 음료조성물은 유통되지 않고 있는 실정이다.However, there are no beverage compositions on the market for dementia prevention that can help reduce Alzheimer's symptoms or improve blood flow.

대한민국 등록특허 제10-0744015호Republic of Korea Patent No. 10-0744015 대한민국 공개특허 제10-2001-0069034호Republic of Korea Patent Publication No. 10-2001-0069034

상기와 같은 문제점을 감안한 본 발명이 해결하고자 하는 과제는, 다양한 유효성분을 혼합하여 치매 증세 경감과 예방에 도움이 되며, 음료를 장기 복용해도 질리지 않을 맛을 제공하고, 당뇨환자가 장기 복용해도 당 수치를 올리지 않을 감미재를 첨가함으로써, 치매에 걸리지 않은 일반 대중들이나 당뇨를 가진 사람들도 수시로 음용할 수 있는 치매예방용 음료조성물을 제공하는 것이다.The problem to be solved by the present invention in consideration of the above problems is to help alleviate and prevent dementia symptoms by mixing various active ingredients, to provide a taste that will not be boring even if the drink is taken for a long period of time, and to reduce the sugar content even if diabetic patients take it for a long time. By adding a sweetener that does not increase the level, we provide a beverage composition for preventing dementia that can be consumed frequently by the general public without dementia or by people with diabetes.

본 발명의 해결하고자 하는 과제는 이상에서 언급된 것들에 한정되지 않으며, 언급되지 아니한 다른 해결과제들은 아래의 기재로부터 당업자에게 명확하게 이해되어 질 수 있을 것이다.The problems to be solved by the present invention are not limited to those mentioned above, and other problems not mentioned can be clearly understood by those skilled in the art from the description below.

상기와 같은 과제를 해결하기 위한 본 발명에 따른 치매예방용 음료조성물은 브로컬리 추출물, 원지 추출물, 석창포 추출물, 흑생강 추출물, 참당귀 뿌리 추출물, 동충하초 추출물, 은행 잎 추출물, 용안육 및 유산균으로 이루어지는 기본 재료와; 비타민 C, 아연으로 이루어지는 활성화 재료;를 포함하는 것을 특징으로 한다.The beverage composition for preventing dementia according to the present invention to solve the above problems is a basic material consisting of broccoli extract, root extract, Aspergillus root extract, black ginger extract, Angelica root extract, Cordyceps sinensis extract, ginkgo leaf extract, longan meat, and lactic acid bacteria. and; It is characterized in that it contains an activating material consisting of vitamin C and zinc.

또한, 본 발명에 따른 치매예방용 음료조성물에 있어서, 흑 구기자, 홍화 씨, 약콩, 녹차, 백복신 및 결명자 중 적어도 하나의 성분을 더 포함하는 것을 특징으로 한다.In addition, in the beverage composition for preventing dementia according to the present invention, it is characterized in that it further contains at least one ingredient among black goji berry, safflower seed, medicinal bean, green tea, white bokshin, and gyeolmyeongja.

또한, 본 발명에 따른 치매예방용 음료조성물에 있어서, 오미자, 감태, 미강 및 블루 아가베 중 적어도 하나의 성분을 더 포함하는 것을 특징으로 한다.In addition, the beverage composition for preventing dementia according to the present invention is characterized in that it further contains at least one ingredient among Schisandra chinensis, Ecklonia cava, rice bran, and blue agave.

또한, 본 발명에 따른 치매예방용 음료조성물에 있어서, 기본 재료는 음료조성물 총 중량에 대하여 0.1~10중량% 함유할 수 있고, 활성화 재료는 0.01~0.1중량% 함유하는 것을 예시할 수 있으나, 이에 한정되는 것은 아니다.In addition, in the beverage composition for preventing dementia according to the present invention, the base material may contain 0.1 to 10% by weight based on the total weight of the beverage composition, and the activating material may contain 0.01 to 0.1% by weight. It is not limited.

또한, 본 발명에 따른 치매예방용 음료조성물에 있어서, 흑 구기자, 홍화 씨, 약콩, 녹차, 백복신, 결명자, 오미자, 감태, 미강 및 블루 아가베는 각각 0.01~1중량% 함유하는 것을 예시할 수 있으나, 이에 한정되는 것은 아니다.In addition, in the beverage composition for preventing dementia according to the present invention, black goji berry, safflower seed, medicinal bean, green tea, white bokshin, Cassia chinensis, Schisandra chinensis, gamtae, rice bran, and blue agave may each be contained 0.01 to 1% by weight. , but is not limited to this.

본 발명에 따른 피치매예방용 음료조성물에 따르면, 다양한 유효성분을 혼합하여 치매 증세 경감과 예방에 도움이 되며, 음료를 장기 복용해도 질리지 않을 맛을 제공하고, 당뇨환자가 장기 복용해도 당 수치를 올리지 않을 감미재를 첨가함으로써, 치매에 걸리지 않은 일반 대중들이나 당뇨를 가진 사람들도 수시로 음용할 수 있는 효과가 있다.According to the beverage composition for preventing pitch itch according to the present invention, it helps alleviate and prevent dementia symptoms by mixing various active ingredients, provides a taste that will not be boring even if the drink is taken for a long period of time, and reduces sugar levels even if diabetic patients take it for a long time. By adding sweeteners that are not intended to be sweetened, even the general public without dementia or people with diabetes can drink it on a regular basis.

또한, 본 발명의 목적은 폐 기능 활성화 및 혈중 산소농도 증강에 도움이 성분을 추가함으로써, 음료를 복용할 경우 이 약효가 혈액을 통해 뇌의 해마조직이나 신경세포에 효율적으로 전달되도록 하는 효과가 있다.In addition, the purpose of the present invention is to add ingredients that help activate lung function and increase oxygen concentration in the blood, so that when the drink is taken, the medicinal effect is efficiently delivered to the hippocampus tissue or nerve cells of the brain through the blood. .

본 발명의 효과는 이상에서 언급된 것들에 한정되지 않으며, 언급되지 아니한 다른 해결과제들은 아래의 기재로부터 당업자에게 명확하게 이해되어 질 수 있을 것이다.The effects of the present invention are not limited to those mentioned above, and other problems not mentioned can be clearly understood by those skilled in the art from the description below.

본 발명을 설명함에 있어서, 관련된 공지기능 혹은 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우 그 상세한 설명은 생략한다. 또한, 후술되는 용어들은 본 발명에서의 기능을 고려하여 정의된 용어들로서 이는 사용자의 의도 또는 판례 등에 따라 달라질 수 있다. 그러므로 그 정의는 본 명세서 전반에 걸친 내용을 토대로 내려져야 할 것이다.In describing the present invention, if a detailed description of a related known function or configuration is judged to unnecessarily obscure the gist of the present invention, the detailed description will be omitted. In addition, the terms described below are terms defined in consideration of functions in the present invention, and may vary depending on the user's intention or precedent. Therefore, the definition should be made based on the contents throughout this specification.

본 발명에 따른 치매예방용 음료조성물은 유효성분으로서 기본 재료와, 활성화 재료를 포함하여 이루어진다.The beverage composition for preventing dementia according to the present invention includes a basic material as an active ingredient and an activating material.

상기 기본 재료는 브로컬리 추출물, 원지 추출물, 석창포 추출물, 흑생강 추출물, 참당귀 뿌리 추출물, 동충하초 추출물, 은행 잎 추출물, 용안육 및 유산균으로 이루어지는 것을 예시할 수 있다.The basic material may include broccoli extract, root extract, Aspergillus root extract, black ginger extract, Angelica root extract, Cordyceps sinensis extract, Ginkgo biloba leaf extract, longan meat, and lactic acid bacteria.

기본 재료를 구성하는 각 추출물은 열수 추출, 초임계 추출, 유기 용매 추출 등 추출 방식으로 이루어지는 것을 예시할 수 있으나, 이에 한정되는 것은 아니다.Each extract constituting the basic material may be made by extraction methods such as hot water extraction, supercritical extraction, and organic solvent extraction, but is not limited thereto.

상기 브로컬리 추출물에는 유효성분으로서 설포라판(sulforaphane)이 함유되어 있는데, 상기 설포라판은 강력한 항산화 효과를 갖는 것으로서, 대장암, 유방암, 전립선암 등의 암 발병 위험을 감소 및 각종 성인병 예방에 효과적이라고 알려져 있으며, 특히 치매를 일으키는 단백질인 베타 아밀로이드 및 타우의 감소 효능을 가지고 있다.The broccoli extract contains sulforaphane as an active ingredient. Sulforaphane has a strong antioxidant effect and is known to be effective in reducing the risk of developing cancer such as colon cancer, breast cancer, and prostate cancer and in preventing various adult diseases. In particular, it has the effect of reducing beta-amyloid and tau, proteins that cause dementia.

상기 원지 추출물에는 유효성분으로서 원지사포닌(Onjisaponin) A~G, 테누이딘(Tenuidine)，테누이폴린(Tenuifdin) 등이 함유되어 있으며, 기억력 증강과 건망증 치료에 좋고 두뇌 활동을 활발하게 해주는 등 인지능력 향상 및 기억력 개선，노인성 치매 예방，항우울증 효과가 있다.The extract contains Onjisaponin A~G, Tenuidine, Tenuifdin, etc. as active ingredients, and is good for improving memory and treating forgetfulness, activating brain activity, etc. It improves ability and memory, prevents senile dementia, and has antidepressant effects.

상기 석창포 추출물은 뇌신경 보호, 기억력 증진 및 인지능력 개선 효능이 있다.The extract of Aspergillus chinensis has the effect of protecting brain nerves, improving memory, and improving cognitive ability.

상기 흑생강 추출물에는 유효성분으로서 사포닌, 아르기닌 등이 함유되어 있으며, 사포닌은 LDL 콜레스테롤을 저하시켜 혈관 강화, 혈류 개선 및 혈액 정화에 효과가 있고, 아르기닌은 혈관을 확장시켜 혈액 순환에 도움이 되며 항산화작용을 하는 것으로 알려져 있다.The black ginger extract contains saponin and arginine as active ingredients. Saponin lowers LDL cholesterol and is effective in strengthening blood vessels, improving blood flow, and purifying blood. Arginine dilates blood vessels, helps blood circulation, and is an antioxidant. It is known to work.

상기 참당귀 뿌리 추출물에는 유효성분으로서 데쿠르신(decursin), 데커시놀 안젤레이트(decursinol angelate) 등이 함유되어 있으며, 데쿠르신은 뇌세포의 손상을 막고 독성을 차단하여 뇌를 보호하고 뇌경색과 치매를 예방하는 효과가 있고, 데커시놀 안젤레이트는 항산화, 항노화 작용을 하는 것으로 알려져 있다.The Angelica root extract contains decursin and decursinol angelate as active ingredients, and decursin protects the brain by preventing damage to brain cells and blocking toxicity, preventing cerebral infarction and dementia. It is effective in preventing , and decursinol angelate is known to have antioxidant and anti-aging effects.

상기 동충하초 추출물에는 유효성분으로서 코디세핀(Cordycepin)이 함유되어 있으며, 코디세핀은 심혈관 건강은 물론, 항암, 항염, 항바이러스에 효과적인 것으로 알려져 있다.The Cordyceps sinensis extract contains cordycepin as an active ingredient, and cordycepin is known to be effective for cardiovascular health as well as anti-cancer, anti-inflammatory, and antiviral.

상기 은행 잎 추출물에는 유효성분으로서 폴리페놀의 일종인 폴라보노이드(비타민 P)가 함유되어 있는데, 폴라보노이드는 혈행 개선, 해마세포 재생 등에 효과가 있다.The ginkgo leaf extract contains flavonoid (vitamin P), a type of polyphenol, as an active ingredient, and flavonoid is effective in improving blood circulation and regenerating hippocampal cells.

상기 용안육 또는 용안육 추출물은 심신 안정에 도움을 준다.The yongan yuk or yongan yuk extract helps stabilize the mind and body.

상기 유산균은 알츠하이머병 환자의 인지 기능, 기억력을 개선하는 데 도움을 준다.The lactic acid bacteria help improve cognitive function and memory in Alzheimer's disease patients.

상기 활성화 재료는 기본재료의 기능을 활성화시키는 역할을 하는 것으로서, 비타민 C와, 아연을 예시할 수 있다.The activating material serves to activate the function of the basic material, and examples include vitamin C and zinc.

상기 비타민 C는 항산화 작용 및 모세혈관 강화 작용을 하며, 상기 아연은 비타민C와 함께 콜라겐의 합성, 세포막의 항산화 역할(세포재생)을 한다.The vitamin C acts as an antioxidant and strengthens capillaries, and the zinc, together with vitamin C, plays a role in the synthesis of collagen and as an antioxidant for cell membranes (cell regeneration).

본 발명에서는 기본재료와 함께 흑 구기자, 홍화 씨, 약콩, 녹차, 백복신 및 결명자 중 적어도 하나의 성분을 더 포함할 수 있으며, 이들 성분들은 분말 형태로 가공하거나 또는 열수추출 등을 통해서 유효성분을 추출하여 사용할 수 있다.In the present invention, in addition to the basic ingredients, at least one ingredient of black goji berry, safflower seed, medicinal bean, green tea, white bokxin, and cassia may be further included, and these ingredients are processed into powder form or the active ingredients are extracted through hot water extraction, etc. You can use it.

상기 흑 구기자에는 류신, 메티오닌, 페닐알라닌, 이소류신 등의 아미노산이 많이 함유되어 있고 무기염류, 베타카로틴, 비타민C 등이 다량으로 함유되어 있고, 이러한 생리활성 물질에 의하여 항산화 작용이 매우 큰 것으로 알려져 있으며 간 기능보호, 콜레스테롤 제거, 자양강장 등의 효능이 있는 것으로 알려져 있다. The black goji berry contains a lot of amino acids such as leucine, methionine, phenylalanine, and isoleucine, as well as a large amount of inorganic salts, beta-carotene, and vitamin C. It is known to have a very strong antioxidant effect due to these bioactive substances, and is known to have a great antioxidant effect on the liver. It is known to have effects such as functional protection, cholesterol removal, and nutritional tonic.

또한, 흑 구기자에는 안토시아닌의 함유량이 매우 많아 수면장애 개선과 항노화, 피부주름억제, 피부재생 효과 등이 있고, 혈액순환을 개선시키고 혈관의 탄력을 증강시켜 심혈관질환을 개선하는 효과가 있다.In addition, black goji berry has a very high anthocyanin content, which has the effect of improving sleep disorders, anti-aging, suppressing skin wrinkles, and skin regeneration. It also has the effect of improving cardiovascular disease by improving blood circulation and enhancing the elasticity of blood vessels.

상기 홍화 씨에는 리놀산(비타민 F)과, 비타민 E가 함유되어 있기 때문에 지방 분해, 혈관 속 콜레스테롤 제거, 혈액순환개선, 항노화 및 항산화 효과가 있는 것으로 알려져 있다.Since the safflower seeds contain linoleic acid (vitamin F) and vitamin E, they are known to have decomposition of fat, removal of cholesterol in blood vessels, improvement of blood circulation, anti-aging, and antioxidant effects.

상기 약콩은 사이토카인 생성을 촉진하는데, 사이토카인은 면역세포에서 생성되는 단백질 중재자로 외부 항원에 대한 여러 면역세포간의 협력을 중재하므로 이들의 생성과 분비는 면역기능을 향상시키는 데 매우 중요하다.The medicinal bean promotes the production of cytokines. Cytokines are protein mediators produced in immune cells and mediate cooperation between various immune cells against external antigens, so their production and secretion are very important in improving immune function.

상기 녹차 잎에는 '카테킨(catechins)'이라 불리는 폴리페놀 성분 등이 풍부하게 들어 있으며, LDL 콜레스테롤 수준을 낮추고, 혈액 흐름을 원활하게 해주며, 혈관의 염증반응을 예방하는 등의 효과가 있다. 특히 카테킨(catechins) 중 하나인 '에피갈로카테킨 갈레이트(epigallocatechin gallate: EGCG)'는 산화 스트레스로부터 뇌세포를 보호하고 기억력을 증강시키는 역할을 한다.The green tea leaves are rich in polyphenols called 'catechins' and have the effect of lowering LDL cholesterol levels, facilitating blood flow, and preventing inflammatory reactions in blood vessels. In particular, 'epigallocatechin gallate (EGCG)', one of the catechins, protects brain cells from oxidative stress and plays a role in enhancing memory.

상기 백복신은 소나무 뿌리에 기생하는 균류로서, 심장을 보해 마음을 평안하게 해준다고 알려져 있으며, 혈관을 안정시키는 작용을 한다.The Baekboksin is a fungus that lives on the roots of pine trees, and is known to nourish the heart and provide peace of mind, and has the effect of stabilizing blood vessels.

상기 결명자에는 카로틴과 안트라퀴논 성분이 함유되어 있는데, 카로틴은 눈의 피로회복을 돕고 야맹증을 예방하며, 안트라퀴논은 강장, 이뇨, 고혈압, 혈관 건강 등에 효과가 있다.The above-mentioned absence contains carotene and anthraquinone. Carotene helps recover from eye fatigue and prevents night blindness, and anthraquinone is effective in tonic, diuretic, high blood pressure, and vascular health.

한편, 본 발명에서는 기본재료와 함께 폐기능 활성화 및 혈중산소 농도 증대에 도움이 되는 오미자 및 감태와, 맛과 영양을 개선시키는 미강과, 감미료 역할을 하는 블루 아가베 등을 더 포함할 수 있으며, 이들 성분들은 분말 형태로 가공하거나 또는 열수추출 등을 통해서 유효성분을 추출하여 사용할 수 있다.Meanwhile, in the present invention, along with the basic ingredients, Schisandra chinensis and Ecklonia cava, which help activate lung function and increase blood oxygen concentration, rice bran, which improves taste and nutrition, and blue agave, which acts as a sweetener, may be further included. Ingredients can be processed into powder form or the active ingredients can be extracted and used through hot water extraction.

한편, 본 발명의 상세한 설명에서는 구체적인 실시예에 관해 설명하였으나, 본 발명은 개시된 실시예에 한정되지 않고 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자에게 있어 본 발명의 기술적 사상을 벗어나지 않는 범위 내에서 여러 가지 치환, 변형 및 변경이 가능하다. 따라서, 본 발명의 범위는 설명된 실시예에 국한되어 정해져서는 안되며 후술하는 특허청구범위뿐만 아니라 이 특허청구범위와 균등한 것들을 포함하는 것으로 해석되어야 할 것이다.Meanwhile, although specific embodiments have been described in the detailed description of the present invention, the present invention is not limited to the disclosed embodiments and is within the scope of the technical spirit of the present invention to those skilled in the art to which the present invention pertains. Various substitutions, modifications and changes are possible within. Accordingly, the scope of the present invention should not be limited to the described embodiments and should be construed to include not only the claims described below but also those equivalent to the claims.

Claims (3)

브로컬리 추출물, 원지 추출물, 석창포 추출물, 흑생강 추출물, 참당귀 뿌리 추출물, 동충하초 추출물, 은행 잎 추출물, 용안육 및 유산균으로 이루어지는 기본 재료와;
비타민 C, 아연으로 이루어지는 활성화 재료;
를 포함하는 것을 특징으로 하는 치매예방용 음료조성물.
Basic ingredients consisting of broccoli extract, root extract, Aspergillus root extract, black ginger extract, Angelica root extract, Cordyceps sinensis extract, ginkgo leaf extract, longan meat and lactic acid bacteria;
Activating ingredients consisting of vitamin C and zinc;
A beverage composition for preventing dementia, comprising:
 제1항에 있어서,
흑 구기자, 홍화 씨, 약콩, 녹차, 백복신 및 결명자 중 적어도 하나의 성분을 더 포함하는 것을 특징으로 하는 치매예방용 음료조성물.
According to paragraph 1,
A beverage composition for preventing dementia, characterized in that it further contains at least one ingredient selected from the group consisting of black goji berry, safflower seed, medicinal soybean, green tea, white bokshin, and gyeolmyeongja.
 제1항에 있어서,
오미자, 감태, 미강 및 블루 아가베 중 적어도 하나의 성분을 더 포함하는 것을 특징으로 하는 치매예방용 음료조성물.
According to paragraph 1,
A beverage composition for preventing dementia, further comprising at least one of Schisandra chinensis, Ecklonia cava, rice bran, and blue agave.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010069034A (en) 2000-01-11 2001-07-23 박길래 Composition of drink for improving dementia and activating brain functions using herbs
KR100744015B1 (en) 2006-03-06 2007-07-30 길기정 Health drink for dementia prevention using a chinese medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010069034A (en) 2000-01-11 2001-07-23 박길래 Composition of drink for improving dementia and activating brain functions using herbs
KR100744015B1 (en) 2006-03-06 2007-07-30 길기정 Health drink for dementia prevention using a chinese medicine

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