KR20230128312A - 두경부 편평세포 암종 및 기타 암에 대한 면역요법에서의사용을 위한 신규 펩티드 및 골격 - Google Patents
두경부 편평세포 암종 및 기타 암에 대한 면역요법에서의사용을 위한 신규 펩티드 및 골격 Download PDFInfo
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- KR20230128312A KR20230128312A KR1020237025497A KR20237025497A KR20230128312A KR 20230128312 A KR20230128312 A KR 20230128312A KR 1020237025497 A KR1020237025497 A KR 1020237025497A KR 20237025497 A KR20237025497 A KR 20237025497A KR 20230128312 A KR20230128312 A KR 20230128312A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
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- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662379864P | 2016-08-26 | 2016-08-26 | |
| DE102016115974 | 2016-08-26 | ||
| US62/379,864 | 2016-08-26 | ||
| DE102016115974.3 | 2016-08-26 | ||
| PCT/EP2017/071347 WO2018037085A1 (en) | 2016-08-26 | 2017-08-24 | Novel peptides and scaffolds for use in immunotherapy against head and neck squamous cell carcinoma and other cancers |
| KR1020197008490A KR20190039812A (ko) | 2016-08-26 | 2017-08-24 | 두경부 편평 세포 암종 및 기타 암에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 골격 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197008490A Division KR20190039812A (ko) | 2016-08-26 | 2017-08-24 | 두경부 편평 세포 암종 및 기타 암에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 골격 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230128312A true KR20230128312A (ko) | 2023-09-04 |
Family
ID=59738331
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197008490A Ceased KR20190039812A (ko) | 2016-08-26 | 2017-08-24 | 두경부 편평 세포 암종 및 기타 암에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 골격 |
| KR1020237025497A Ceased KR20230128312A (ko) | 2016-08-26 | 2017-08-24 | 두경부 편평세포 암종 및 기타 암에 대한 면역요법에서의사용을 위한 신규 펩티드 및 골격 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197008490A Ceased KR20190039812A (ko) | 2016-08-26 | 2017-08-24 | 두경부 편평 세포 암종 및 기타 암에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 골격 |
Country Status (19)
| Country | Link |
|---|---|
| US (17) | US10376542B2 (enExample) |
| EP (2) | EP3988563A3 (enExample) |
| JP (3) | JP2019536426A (enExample) |
| KR (2) | KR20190039812A (enExample) |
| CN (2) | CN119060129A (enExample) |
| AU (2) | AU2017315139B2 (enExample) |
| BR (1) | BR112019003513A2 (enExample) |
| CA (1) | CA3033115A1 (enExample) |
| CL (4) | CL2019000460A1 (enExample) |
| CO (1) | CO2019002466A2 (enExample) |
| CR (4) | CR20210067A (enExample) |
| MA (1) | MA46037A (enExample) |
| MX (2) | MX2019002067A (enExample) |
| MY (1) | MY198110A (enExample) |
| PE (1) | PE20190628A1 (enExample) |
| PH (1) | PH12019500313A1 (enExample) |
| SG (2) | SG11201901176XA (enExample) |
| TW (2) | TW202304970A (enExample) |
| WO (1) | WO2018037085A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3319985T (pt) | 2015-07-06 | 2021-01-06 | Immatics Biotechnologies Gmbh | Novos péptidos e combinação de péptidos para uso em imunoterapia do cancro do esófago e outros cancros |
| GB201604490D0 (en) | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
| TW202304970A (zh) | 2016-08-26 | 2023-02-01 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
| DE102018107224A1 (de) * | 2018-02-21 | 2019-08-22 | Immatics Biotechnologies Gmbh | Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
| TWI852977B (zh) * | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| CN113151285B (zh) * | 2019-12-30 | 2023-01-24 | 白素梅 | 人4IgB7-H3的突变编码基因及其调节免疫的应用 |
| IL296881A (en) * | 2020-04-14 | 2022-12-01 | Universit? De Montr?Al | New antigens specific for acute myeloid leukemia (aml) and their uses |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| CN112245564A (zh) * | 2020-11-03 | 2021-01-22 | 哈尔滨医科大学 | 一种注射用血管生成抑肽冻干制剂及其冻干方法 |
| CN115403666B (zh) * | 2021-05-26 | 2025-08-12 | 中国农业大学 | 抗流感病毒多肽及其应用 |
| WO2025018697A1 (ko) * | 2023-07-14 | 2025-01-23 | 전남대학교산학협력단 | 암 진단을 위한 시료 처리 방법 및 이를 이용한 암 진단에 대한 정보 제공 방법 |
| WO2025257278A1 (en) * | 2024-06-12 | 2025-12-18 | Boehringer Ingelheim International Gmbh | Immunogenic sequences |
| CN118956629A (zh) * | 2024-07-24 | 2024-11-15 | 佳吾益(北京)科技有限公司 | 表达真正表位接受型mhc胞外结构域的工程化细胞 |
| CN120168640A (zh) * | 2025-05-23 | 2025-06-20 | 四川省医学科学院·四川省人民医院 | 抑制或沉默lap3活性的物质在制备治疗肿瘤和/或延缓李斯特菌浸入的药物中的应用 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440859A (en) | 1977-05-27 | 1984-04-03 | The Regents Of The University Of California | Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms |
| US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| NZ192465A (en) | 1978-12-22 | 1983-09-30 | Biogen Nv | Recombinant dna molecule comprising gene coding for polypeptide displaying hbv (hepatitis b virus) antigenicity usesthereof |
| US4530901A (en) | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
| US4342566A (en) | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
| US4678751A (en) | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4766075A (en) | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US4582800A (en) | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4757006A (en) | 1983-10-28 | 1988-07-12 | Genetics Institute, Inc. | Human factor VIII:C gene and recombinant methods for production |
| US4677063A (en) | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US4810648A (en) | 1986-01-08 | 1989-03-07 | Rhone Poulenc Agrochimie | Haloarylnitrile degrading gene, its use, and cells containing the gene |
| US4897445A (en) | 1986-06-27 | 1990-01-30 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide bond |
| CA2163032C (en) | 1993-06-03 | 2001-02-06 | John Landon | Antibody fragments in therapy |
| AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| ATE244300T1 (de) | 1996-01-17 | 2003-07-15 | Imp College Innovations Ltd | Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl) |
| US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6783961B1 (en) * | 1999-02-26 | 2004-08-31 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| US7238790B2 (en) * | 1999-01-12 | 2007-07-03 | Genentech, Inc. | PRO1313 polypeptides |
| CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| EP2316950A1 (en) | 2000-03-27 | 2011-05-04 | Technion Research and Development Foundation, Ltd. | Single chain class I major histo-compatibility complexes, constructs encoding same and methods of generating same |
| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| AU2001275246B2 (en) | 2000-06-05 | 2006-06-29 | Altor Bioscience Corporation | T cell receptor fusions and conjugates and methods of use thereof |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| AU2003207628A1 (en) * | 2002-01-18 | 2003-09-02 | Incyte Corporation | Structural and cytoskeleton-associated proteins |
| US6992176B2 (en) | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
| CA2476625A1 (en) | 2002-02-20 | 2003-08-28 | Dyax Corp. | Mhc-peptide complex binding ligands |
| EP1549748B1 (en) | 2002-10-09 | 2014-10-01 | Immunocore Ltd. | Single chain recombinant t cell receptors |
| ES2327229T3 (es) | 2002-11-09 | 2009-10-27 | Immunocore Ltd. | Presentacion del receptor de linfocitos t. |
| GB0304068D0 (en) | 2003-02-22 | 2003-03-26 | Avidex Ltd | Substances |
| ATE461215T1 (de) | 2005-09-05 | 2010-04-15 | Immatics Biotechnologies Gmbh | Tumor-assoziierte peptide, welche an unterschiedliche menschliche leukozytenantigene der klasse ii binden |
| ES2330013T3 (es) * | 2005-09-05 | 2009-12-03 | Immatics Biotechnologies Gmbh | Peptidos asociados a tumores unidos a moleculas del antigeno de leucocito humano (hla) de clase i o ii y vacunas contra el cancer relacionadas. |
| AU2007284651B2 (en) | 2006-08-09 | 2014-03-20 | Institute For Systems Biology | Organ-specific proteins and methods of their use |
| US20100210829A1 (en) | 2007-03-08 | 2010-08-19 | Five Prime Therapeutics, Inc. | Compositions and Methods for Treating Diseases, Disorders, or Conditions Characterized by Myelin Degeneration, Myelin Deficiency or Loss |
| HUE027057T2 (en) * | 2007-07-27 | 2016-08-29 | Immatics Biotechnologies Gmbh | New immunogenic epitope for immunotherapy |
| WO2009036246A2 (en) * | 2007-09-14 | 2009-03-19 | Immunotope, Inc. | Immunogens that induce cytotoxic t-lymphocytes and their use in prevention, treatment, and diagnosis of cancer |
| CN101932598B (zh) * | 2008-01-30 | 2016-12-21 | 皮里斯股份公司 | 具有对人c-met受体酪氨酸激酶的亲和性的泪脂质运载蛋白的突变蛋白及其获得方法 |
| US20090263574A1 (en) | 2008-04-21 | 2009-10-22 | Quinn Daniel E | Method of restoring an article |
| CN102119332A (zh) * | 2008-04-29 | 2011-07-06 | 免疫刺激公司 | 免疫调节组合物及其使用方法 |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| GB201006360D0 (en) | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
| CA2816225A1 (en) | 2010-10-26 | 2012-05-03 | Technion Research & Development Foundation Ltd. | Antibodies which bind soluble t-cell receptor ligands |
| WO2012148720A2 (en) * | 2011-04-27 | 2012-11-01 | The Regents Of The University Of California | Anti-microbial peptides and methods of use thereof |
| CN104081202A (zh) | 2011-09-12 | 2014-10-01 | 克里蒂科斯有限责任公司 | 检测靶分子的非侵入性方法 |
| WO2013057586A1 (en) | 2011-10-19 | 2013-04-25 | Oslo Universitetssykehus Hf | Compositions and methods for producing soluble t - cell receptors |
| AU2013243952A1 (en) * | 2012-04-02 | 2014-10-30 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US20150072922A1 (en) * | 2012-04-17 | 2015-03-12 | The Research Institute At Nationwide Children's Hospital | Rnase 7 antimicrobial peptides |
| ES2603589T3 (es) | 2012-11-08 | 2017-02-28 | F. Hoffmann-La Roche Ag | Ácidos nucleicos que codifican polipéptidos quiméricos para la identificación sistemática de bibliotecas |
| WO2014168242A1 (ja) * | 2013-04-12 | 2014-10-16 | Jnc株式会社 | 歯周病特異的ペプチドに対するモノクローナル抗体およびその用途 |
| EP2808392A1 (en) | 2013-05-28 | 2014-12-03 | Rheinische Friedrich-Wilhelms-Universität Bonn | Aptamers and use of the aptamers in the diagnosis and treatment of cancer |
| TWI636065B (zh) * | 2013-08-05 | 2018-09-21 | 伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物 |
| GB201319446D0 (en) * | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
| GB201408255D0 (en) * | 2014-05-09 | 2014-06-25 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML) |
| GB201411037D0 (en) * | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
| GB201507030D0 (en) | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| GB201511792D0 (en) * | 2015-07-06 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers |
| EP3446119A1 (en) | 2016-04-18 | 2019-02-27 | The Broad Institute Inc. | Improved hla epitope prediction |
| TW202304970A (zh) | 2016-08-26 | 2023-02-01 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
| JP7405688B2 (ja) | 2020-05-14 | 2023-12-26 | 本田技研工業株式会社 | 情報処理装置、車両シェアリングシステム、情報処理方法、及びプログラム。 |
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