KR20230115122A - A medicine for treating dermatophytosis - Google Patents

Abstract

The present invention discloses a therapeutic agent for ringworm and a method for preparing the same. Treatments for ringworm include the following ingredients:
Coix Seed 5-13 parts by weight, Prunella vulgaris 11-17 parts by weight, Golden (Scutellaria baicalensis) 6-12 parts by weight, Cortex Phellodendri Chinensis 2-7 parts by weight, Rhizoma Coptidis 3-7 parts by weight, water 300-700 parts by weight, alum 3-7 parts by weight, gold (Scutellaria baicalensis Genorgi) 5-12 parts by weight and windbreak (Radix Saposhnikoviae) 6-9 parts by weight.

Description

Ringworm Treatment {A MEDICINE FOR TREATING DERMATOPHYTOSIS}

The present invention relates to the field of medical health, and more particularly to a therapeutic agent for ringworm and a method for producing the same.

Ringworm is a very common disease. Although many people suffer from ringworm, there is a lack of drugs and methods to effectively treat ringworm.

Ringworm is a highly contagious foot skin disease caused by a pathogenic fungus. There are no sebaceous glands between the soles and toes, so the fatty acids that suppress filamentous fungi on the skin are lacking, and the physiological defense function is weak. On the other hand, skin sweat glands are abundant in these locations, resulting in frequent sweating, which promotes the growth of filamentous fungi along with poor air circulation and local moisture and warmth. In addition, there is a thick stratum corneum on the soles of the feet, and keratin in the stratum corneum supplies rich nutrients to fungi and promotes fungal growth.

Most existing ringworm treatments use ingredients containing salicylic acid. However, these raw materials can cause serious damage to the patient's skin, cannot completely cure ringworm, and can easily recur. In addition, these drugs have an unpleasant odor and irritation, and can easily irritate the patient's respiratory tract and cause side effects.

An object of the present invention is to provide a therapeutic agent for ringworm and a method for preparing the same, which can overcome the disadvantages of the prior art.

The present invention discloses a therapeutic agent for ringworm prepared using the following raw materials:

Coix Seed 5-13 parts by weight, Prunella vulgaris 11-17 parts by weight, Golden (Scutellaria baicalensis) 6-12 parts by weight, Cortex Phellodendri Chinensis 2-7 parts by weight, Rhizoma Coptidis 3-7 parts by weight and 300-700 parts by weight of water.

The present invention also provides a method for preparing a medicament for treating ringworm, comprising the following steps:

Step 1: Wash all raw materials with clean water;

2nd step: mechanically pulverizing uiyiin, Lamiaceae and golden, respectively; drying the pulverized raw material under infrared heating; Grinding each of the dried raw materials; filtering the ground raw material through a filter screen; 5-13 parts by weight of the filtered raw material Uiyin, 11-17 parts by weight of Lamiaceae and 6-12 parts by weight of gold are mixed to obtain powder A;

Step 3: mechanically pulverize yellow white, yellow lotus, alum, gold (Scutellaria baicalensis Genorgi) and windbreak (Radix Saposhnikoviae), respectively; freeze-drying the pulverized raw material; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 2-7 parts by weight of the filtered raw material yellow white, 3-7 parts by weight of yellow lotus, 3-7 parts by weight of alum, 5-12 parts by weight of gold, and 6-9 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mix the powder A and the powder B, add 300-700 parts by weight of water, soak for 2 hours and boil the resultant, filter twice to obtain a clear liquid, and cool the clear liquid to ringworm Get a cure for layer treatment.

The ringworm therapeutic agent of the present invention has a rapid onset, no side effects, and a low recurrence rate.

Example 1

Step 1: wash all raw materials with clean water at 20°C;

Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying at 50° C. for 3 hours under infrared heating; Grinding the dried raw material; filtering the ground raw material through a filter screen allowing a particle size of 60 mesh; 5 parts by weight of the filtered raw material Uiin, 17 parts by weight of Lamiaceae and 6 parts by weight of gold were mixed to obtain powder A;

Step 3: mechanically pulverize Cortex Phellodendri Chinensis, Rhizoma Coptidis, alum, Scutellaria baicalensis Genorgi, and Radix Saposhnikoviae; Freeze-drying the pulverized raw material at -4° C. for 4 hours; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 2 parts by weight of the filtered raw material yellow white, 7 parts by weight of yellow lotus, 3 parts by weight of alum, 12 parts by weight of gold, and 6 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mixing the powder A and the powder B, adding 300 parts by weight of water, soaking for 2 hours, boiling the resultant, filtering twice to obtain a clear liquid, and cooling the clear liquid to treat ringworm get a cure for

Example 2

Step 1: wash all raw materials with clean water at 20°C;

Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying at 50° C. for 3 hours under infrared heating; Grinding the dried raw material; filtering the ground raw material through a filter screen allowing a particle size of 60 mesh; 13 parts by weight of the filtered raw material Uiyin, 11 parts by weight of Lamiaceae, and 12 parts by weight of gold were mixed to obtain powder A;

Step 3: mechanically pulverize Cortex Phellodendri Chinensis, Rhizoma Coptidis, alum, Scutellaria baicalensis Genorgi, and Radix Saposhnikoviae; Freeze-drying the pulverized raw material at -10 ° C for 4 hours; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 7 parts by weight of the filtered raw material yellow white, 3 parts by weight of yellow lotus, 7 parts by weight of alum, 5 parts by weight of gold, and 9 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mixing the powder A and the powder B, adding 700 parts by weight of water, soaking for 2 hours, boiling the resultant, filtering twice to obtain a clear liquid, and cooling the clear liquid to treat ringworm get a cure for

Example 3

Step 1: wash all raw materials with clean water at 20°C;

Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying at 50° C. for 3 hours under infrared heating; Grinding the dried raw material; filtering the ground raw material through a filter screen allowing a particle size of 60 mesh; Powder A was obtained by mixing 8 parts by weight of the filtered raw material Uiyin, 15 parts by weight of Lamiaceae and 7 parts by weight of gold;

Step 3: mechanically pulverize Cortex Phellodendri Chinensis, Rhizoma Coptidis, alum, Scutellaria baicalensis Genorgi, and Radix Saposhnikoviae; Freeze-drying the pulverized raw material at -10 ° C for 4 hours; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 3 parts by weight of the filtered raw material yellow white, 6 parts by weight of yellow lotus, 4 parts by weight of alum, 10 parts by weight of gold, and 7 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mixing the powder A and the powder B, adding 400 parts by weight of water, soaking for 2 hours, boiling the resultant, filtering twice to obtain a clear liquid, and cooling the clear liquid to treat ringworm get a cure for

Example 4

Step 1: wash all raw materials with clean water at 20°C;

Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying at 50° C. for 3 hours under infrared heating; Grinding the dried raw material; filtering the ground raw material through a filter screen allowing a particle size of 60 mesh; Powder A was obtained by mixing 11 parts by weight of the filtered raw material Uiyin, 13 parts by weight of Lamiaceae and 10 parts by weight of gold;

Step 3: mechanically pulverize Cortex Phellodendri Chinensis, Rhizoma Coptidis, alum, Scutellaria baicalensis Genorgi, and Radix Saposhnikoviae; Freeze-drying the pulverized raw material at -10 ° C for 4 hours; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 5 parts by weight of the filtered raw material yellow white, 4 parts by weight of yellow lotus, 6 parts by weight of alum, 6 parts by weight of gold, and 9 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mixing the powder A and the powder B, adding 600 parts by weight of water, soaking for 2 hours, boiling the resultant, filtering twice to obtain a clear liquid, and cooling the clear liquid to treat ringworm get a cure for

Example 5

Step 1: wash all raw materials with clean water at 20°C;

Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying at 50° C. for 3 hours under infrared heating; Grinding the dried raw material; filtering the ground raw material through a filter screen allowing a particle size of 60 mesh; Powder A was obtained by mixing 9 parts by weight of the filtered raw material Uiyin, 14 parts by weight of Lamiaceae and 8 parts by weight of gold;

Step 3: mechanically pulverize Cortex Phellodendri Chinensis, Rhizoma Coptidis, alum, Scutellaria baicalensis Genorgi, and Radix Saposhnikoviae; Freeze-drying the pulverized raw material at -10 ° C for 4 hours; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 4 parts by weight of the filtered raw material yellow white, 5 parts by weight of yellow lotus, 5 parts by weight of alum, 8 parts by weight of gold, and 8 parts by weight of windbreak are mixed to obtain powder B;

Fourth step: mixing the powder A and the powder B, adding 500 parts by weight of water, soaking for 2 hours, boiling the resulting product, filtering twice to obtain a clear liquid, and cooling the clear liquid to treat ringworm get a cure for

comparative example

As a comparative example, a ringworm liquid formulation was prepared in the following step according to the formulation of CN1943697A. Fresh aloe was immersed in white wine (53% ethanol content) for 15 days, garlic was added, and immersed for an additional 7 days, rice vinegar was added, stirred sufficiently, and the clear liquid was collected to obtain a ringworm solution as a comparative example.

The treatment for ringworm prepared in Examples 1 to 5 and the ringworm liquid prepared in Comparative Example were administered to 50 patients with mild symptoms and 50 patients with severe symptoms, respectively, and the effects on the patients after administration are shown in Table 1 below.

Table 1: Effects of Examples 1-5 and Comparative Examples

It can be seen from Table 1 that the ringworm solution of Comparative Example has a general therapeutic effect and a long treatment time. However, the ringworm treatment prepared according to the present invention has a high cure rate and a short treatment time.

Claims (8)

Coix Seed 5-13 parts by weight, Prunella vulgaris 11-17 parts by weight, Golden (Scutellaria baicalensis) 6-12 parts by weight, Cortex Phellodendri Chinensis 2-7 parts by weight, Rhizoma Coptidis 3-7 parts by weight and 300-700 parts by weight of water,
A cure for ringworm. According to claim 1,
Further comprising 3-7 parts by weight of alum, 5-12 parts by weight of golden (Scutellaria baicalensis Genorgi) and 6-9 parts by weight of windproof (Radix Saposhnikoviae),
A cure for ringworm. According to claim 2,
The treatment for ringworm is:
Coix Seed 8-11 parts by weight, Prunella vulgaris 13-15 parts by weight, Golden (Scutellaria baicalensis) 7-10 parts by weight, Cortex Phellodendri Chinensis 3-5 parts by weight, Rhizoma Coptidis 4-6 parts by weight, 400-600 parts by weight of water, 4-6 parts by weight of alum, 6-10 parts by weight of gold (Scutellaria baicalensis Genorgi) and 7-9 parts by weight of windbreak (Radix Saposhnikoviae),
A cure for ringworm. According to claim 2,
The treatment for ringworm is:
9 parts by weight of Coix Seed, 145 parts by weight of Prunella vulgaris, 8 parts by weight of Golden (Scutellaria baicalensis), 4 parts by weight of Cortex Phellodendri Chinensis, 5 parts by weight of Rhizoma Coptidis, 500 parts by weight of water , containing 5 parts by weight of alum, 8 parts by weight of golden (Scutellaria baicalensis Genorgi) and 8 parts by weight of windbreak (Radix Saposhnikoviae),
A cure for ringworm. A method for preparing a therapeutic agent for ringworm according to claim 1 comprising the following steps:
Step 1: Wash all raw materials with clean water;
Step 2: Mechanically pulverizing Coix Seed, Prunella vulgaris and Scutellaria baicalensis respectively; drying the pulverized raw material under infrared heating; Grinding each of the dried raw materials; filtering the ground raw material through a filter screen; 5-13 parts by weight of the filtered raw material Uiyin, 11-17 parts by weight of Lamiaceae and 6-12 parts by weight of gold are mixed to obtain powder A;
Step 3: Mechanically pulverize Cortex Phellodendri Chinensis and Rhizoma Coptidis, respectively; freeze-drying the pulverized raw material; Grinding the freeze-dried raw material; filtering the ground raw material through a filter screen; 2 to 7 parts by weight of the filtered raw material yellow white and 3 to 7 parts by weight of yellow lotus are mixed to obtain powder B;
Fourth step: mix the powder A and the powder B, add 300-700 parts by weight of water, soak for 2 hours and boil the resultant, filter twice to obtain a clear liquid, and cool the clear liquid to ringworm Get a cure for layer treatment. According to claim 5,
The filter screens in the second stage and the third stage allow for a 60 mesh particle size.
A manufacturing method for ringworm treatment. According to claim 5,
Drying under infrared heating in the second step is carried out at 50 ° C. for 3 hours,
A manufacturing method for ringworm treatment. According to claim 5,
Freeze-drying in the third step is carried out at -10 ° C for 4 hours,
A manufacturing method for ringworm treatment.