KR20230097020A - 활성제를 함유하는 안구 임플란트 - Google Patents

활성제를 함유하는 안구 임플란트 Download PDF

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KR20230097020A
KR20230097020A KR1020237014006A KR20237014006A KR20230097020A KR 20230097020 A KR20230097020 A KR 20230097020A KR 1020237014006 A KR1020237014006 A KR 1020237014006A KR 20237014006 A KR20237014006 A KR 20237014006A KR 20230097020 A KR20230097020 A KR 20230097020A
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South Korea
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implant
sustained release
release biodegradable
active agent
ocular implant
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Korean (ko)
Inventor
찰스 디 블리자드
아서 드리스콜
라미 엘-하이에크
마이클 골드스타인
조셉 이아코나
피터 자렛
티모시 에스 자렛
에리카 칸
재커리 라트렐
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오큘라 테라퓨틱스, 인코포레이티드
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Publication of KR20230097020A publication Critical patent/KR20230097020A/ko
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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US202163209725P 2021-06-11 2021-06-11
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WO2022251710A2 (en) 2021-05-28 2022-12-01 Sight Sciences, Inc. Intraocular devices, systems, and methods
US20260108561A1 (en) * 2022-10-04 2026-04-23 National University Of Singapore Composition for cell transplantation therapy and the use thereof
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
PE20260040A1 (es) * 2023-04-11 2026-01-09 Ocular Therapeutix Inc Implante ocular que contiene un inhibidor de la tirosina cinasa
CN120459009A (zh) * 2024-04-29 2025-08-12 浙江瑞瞳生物科技有限公司 可降解泪小管插入剂及制备方法
WO2025248489A1 (en) * 2024-05-29 2025-12-04 Sight Sciences, Inc. Bio-erodible ocular implants for treatment of conditions of the eye
WO2025255203A1 (en) * 2024-06-06 2025-12-11 Ocular Therapeutix, Inc. Compositions and methods for treating ocular diseases
CN119185164A (zh) * 2024-09-09 2024-12-27 沈阳药科大学 一种高载药量的抗vegf眼内缓释植入剂及其制备方法
CN120571053A (zh) * 2025-06-19 2025-09-02 青岛大学附属医院 一种用于密封视网膜裂孔的可荧光示踪的水凝胶材料及其制备方法与应用

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CN114533648B (zh) * 2020-11-26 2026-04-07 成都康弘药业集团股份有限公司 一种阿西替尼眼内植入剂

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