MX2023004614A - Implante ocular que contiene un agente activo. - Google Patents

Implante ocular que contiene un agente activo.

Info

Publication number
MX2023004614A
MX2023004614A MX2023004614A MX2023004614A MX2023004614A MX 2023004614 A MX2023004614 A MX 2023004614A MX 2023004614 A MX2023004614 A MX 2023004614A MX 2023004614 A MX2023004614 A MX 2023004614A MX 2023004614 A MX2023004614 A MX 2023004614A
Authority
MX
Mexico
Prior art keywords
ocular implant
implant containing
active agent
hydrogel
treatment
Prior art date
Application number
MX2023004614A
Other languages
English (en)
Inventor
Peter Jarrett
Michael Goldstein
Rami El-Hayek
Timothy S Jarrett
Charles D Blizzard
Arthur Driscoll
Joseph Iacona
Erica Kahn
Zachary Lattrell
Original Assignee
Ocular Therapeutix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ocular Therapeutix Inc filed Critical Ocular Therapeutix Inc
Publication of MX2023004614A publication Critical patent/MX2023004614A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/16—Amides, e.g. hydroxamic acids
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/47—Quinolines; Isoquinolines
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Abstract

La invención se refiere a un implante ocular biodegradable de liberación sostenida que contiene un inhibidor de tirosina quinasa disperso en un hidrogel para el tratamiento de una enfermedad de la retina durante un período de tiempo prolongado.
MX2023004614A 2020-10-27 2021-10-26 Implante ocular que contiene un agente activo. MX2023004614A (es)

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US202063106270P 2020-10-27 2020-10-27
US202163165423P 2021-03-24 2021-03-24
US202163209725P 2021-06-11 2021-06-11
PCT/US2021/056648 WO2022093818A1 (en) 2020-10-27 2021-10-26 Ocular implant containing an active agent

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KR (1) KR20230097020A (es)
CN (1) CN116419755A (es)
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WO2021195163A1 (en) * 2020-03-25 2021-09-30 Ocular Therapeutix, Inc. Ocular implant containing a tyrosine kinase inhibitor
WO2024076303A1 (en) * 2022-10-04 2024-04-11 National University Of Singapore Composition for cell transplantation therapy and the use thereof

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* Cited by examiner, † Cited by third party
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US10226417B2 (en) * 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
EP4279064A3 (en) * 2015-05-12 2024-02-28 Incept, LLC Drug delivery from hydrogels
WO2021195163A1 (en) * 2020-03-25 2021-09-30 Ocular Therapeutix, Inc. Ocular implant containing a tyrosine kinase inhibitor
CN114533648A (zh) * 2020-11-26 2022-05-27 成都康弘药业集团股份有限公司 一种阿西替尼眼内植入剂

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JP2023547607A (ja) 2023-11-13
CA3192909A1 (en) 2022-05-05
KR20230097020A (ko) 2023-06-30
AU2021367970A1 (en) 2023-05-11
CN116419755A (zh) 2023-07-11
EP4236943A4 (en) 2024-04-24
EP4236943A1 (en) 2023-09-06

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