KR20230082024A - 재프로그래밍을 위한 기능적 단편, 구성 및 이의 응용 - Google Patents
재프로그래밍을 위한 기능적 단편, 구성 및 이의 응용 Download PDFInfo
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- KR20230082024A KR20230082024A KR1020237011913A KR20237011913A KR20230082024A KR 20230082024 A KR20230082024 A KR 20230082024A KR 1020237011913 A KR1020237011913 A KR 1020237011913A KR 20237011913 A KR20237011913 A KR 20237011913A KR 20230082024 A KR20230082024 A KR 20230082024A
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- A—HUMAN NECESSITIES
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C07K14/4702—Regulators; Modulating activity
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
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- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010934192.9A CN114231489A (zh) | 2020-09-08 | 2020-09-08 | 用于重编程的功能性片段、组合及其应用 |
| CN202010934192.9 | 2020-09-08 | ||
| PCT/CN2021/117302 WO2022052964A1 (zh) | 2020-09-08 | 2021-09-08 | 用于重编程的功能性片段、组合及其应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230082024A true KR20230082024A (ko) | 2023-06-08 |
Family
ID=80632100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237011913A Pending KR20230082024A (ko) | 2020-09-08 | 2021-09-08 | 재프로그래밍을 위한 기능적 단편, 구성 및 이의 응용 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240026379A1 (https=) |
| EP (1) | EP4212624A4 (https=) |
| JP (1) | JP7680072B2 (https=) |
| KR (1) | KR20230082024A (https=) |
| CN (2) | CN114231489A (https=) |
| WO (1) | WO2022052964A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117070477A (zh) * | 2022-05-10 | 2023-11-17 | 纽伦捷生物医药科技(上海)有限公司 | 重组溶瘤病毒的重编程的功能性片段、组合及其应用 |
| WO2025108407A2 (en) | 2023-11-23 | 2025-05-30 | Neuexcell Therapeutics (Suzhou) Co., Ltd. | Gene therapy compositions and methods for treating glioma |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010053522A2 (en) * | 2008-10-29 | 2010-05-14 | The Regents Of The University Of California | Methods for identifying and producing neural stem and progenitor cells and their progeny |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| US9057053B2 (en) * | 2010-01-19 | 2015-06-16 | The Board Of Trustees Of The Leland Stanford Junior University | Direct conversion of cells to cells of other lineages |
| EP2531599A4 (en) * | 2010-02-04 | 2014-01-08 | Vivoscript Inc | COMPOSITIONS AND METHODS OF RENEWING CELLS WITHOUT GENETIC MODIFICATION FOR THE TREATMENT OF NEUROLOGICAL SUFFERING |
| WO2014037527A1 (en) * | 2012-09-07 | 2014-03-13 | Cambridge Enterprise Limited | Maturation of mammalian cells by modulation of protein phosphorylation |
| US10076574B2 (en) | 2013-10-25 | 2018-09-18 | Wayne State University | Methods, systems and compositions relating to cell conversion via protein-induced in-vivo cell reprogramming |
| EP3099786A1 (en) * | 2014-01-29 | 2016-12-07 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Trans-differentiation of differentiated cells |
| WO2017081033A1 (en) * | 2015-11-09 | 2017-05-18 | Universite De Nice Sophia Antipolis | Cell differentiation or reprogramming using fezf2 and lmo4 |
| CN107435050B (zh) * | 2017-06-20 | 2021-02-09 | 向孟清 | 一种将人或动物体细胞诱导为神经干细胞的方法 |
| EP3418378B1 (en) * | 2017-06-22 | 2024-12-25 | HI-STEM gGmbH Im Deutschen Krebsforschungszentrum DKFZ | Novel methods for the generation and use of human induced neural border stem cells |
| US20200018746A1 (en) * | 2018-03-14 | 2020-01-16 | The Broad Institute, Inc. | Three-Dimensional Human Neural Tissues for CRISPR-Mediated Perturbation of Disease Genes |
| US20210228741A1 (en) * | 2018-04-27 | 2021-07-29 | University Of Washington | Methods and compositions to stimulate retinal regeneration |
| US20200002679A1 (en) * | 2018-06-05 | 2020-01-02 | Kcellbio Banking Co., Ltd. | Composition for cell regeneration comprising cells hypersecreting growth factors, and at least one of neural stem cells, neurons and gabaergic neurons |
| US20210268126A1 (en) * | 2018-08-23 | 2021-09-02 | Rutgers, The State University Of New Jersey | Treating spinal cord injury (sci) and brain injury using gsx1 |
| CN109385404B (zh) * | 2018-10-19 | 2021-07-06 | 国典(北京)医药科技有限公司 | 一种诱导干细胞分化为神经元的方法及神经元与应用 |
-
2020
- 2020-09-08 CN CN202010934192.9A patent/CN114231489A/zh active Pending
-
2021
- 2021-09-08 JP JP2023515253A patent/JP7680072B2/ja active Active
- 2021-09-08 EP EP21866017.3A patent/EP4212624A4/en active Pending
- 2021-09-08 CN CN202180054720.4A patent/CN116437943A/zh active Pending
- 2021-09-08 WO PCT/CN2021/117302 patent/WO2022052964A1/zh not_active Ceased
- 2021-09-08 US US18/024,504 patent/US20240026379A1/en active Pending
- 2021-09-08 KR KR1020237011913A patent/KR20230082024A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7680072B2 (ja) | 2025-05-20 |
| JP2023540130A (ja) | 2023-09-21 |
| EP4212624A1 (en) | 2023-07-19 |
| WO2022052964A1 (zh) | 2022-03-17 |
| CN114231489A (zh) | 2022-03-25 |
| CN116437943A (zh) | 2023-07-14 |
| EP4212624A4 (en) | 2024-12-18 |
| US20240026379A1 (en) | 2024-01-25 |
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