KR20230048066A - 통증 조절용 관절내 코르티코스테로이드의 약학 조성물 - Google Patents

통증 조절용 관절내 코르티코스테로이드의 약학 조성물 Download PDF

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Publication number
KR20230048066A
KR20230048066A KR1020237006338A KR20237006338A KR20230048066A KR 20230048066 A KR20230048066 A KR 20230048066A KR 1020237006338 A KR1020237006338 A KR 1020237006338A KR 20237006338 A KR20237006338 A KR 20237006338A KR 20230048066 A KR20230048066 A KR 20230048066A
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KR
South Korea
Prior art keywords
pharmaceutical composition
intra
osteoarthritis
pain
human subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237006338A
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English (en)
Korean (ko)
Inventor
쉬에-팡 쉬
칼 오스카 브라운
Original Assignee
티엘씨 바이오파머슈티컬즈 인코포레이티드
타이완 리포좀 캄파니 리미티드
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Application filed by 티엘씨 바이오파머슈티컬즈 인코포레이티드, 타이완 리포좀 캄파니 리미티드 filed Critical 티엘씨 바이오파머슈티컬즈 인코포레이티드
Publication of KR20230048066A publication Critical patent/KR20230048066A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020237006338A 2020-08-05 2021-08-05 통증 조절용 관절내 코르티코스테로이드의 약학 조성물 Pending KR20230048066A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063061395P 2020-08-05 2020-08-05
US63/061,395 2020-08-05
PCT/US2021/044619 WO2022031898A1 (en) 2020-08-05 2021-08-05 Pharmaceutical composition of intra-articular corticosteroid for pain control

Publications (1)

Publication Number Publication Date
KR20230048066A true KR20230048066A (ko) 2023-04-10

Family

ID=77519828

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237006338A Pending KR20230048066A (ko) 2020-08-05 2021-08-05 통증 조절용 관절내 코르티코스테로이드의 약학 조성물

Country Status (13)

Country Link
US (1) US12514820B2 (https=)
EP (1) EP4192426A1 (https=)
JP (1) JP2023537474A (https=)
KR (1) KR20230048066A (https=)
CN (1) CN116348093A (https=)
AU (1) AU2021320774A1 (https=)
BR (1) BR112023001926A2 (https=)
CA (1) CA3187955A1 (https=)
CL (1) CL2023000315A1 (https=)
IL (1) IL300354A (https=)
MX (1) MX2023001410A (https=)
TW (1) TW202220668A (https=)
WO (1) WO2022031898A1 (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2854769T1 (sl) * 2012-07-05 2023-09-29 Taiwan Liposome Company, Ltd. Postopki za zdravljenje artritisa
ES2985871T3 (es) * 2017-03-14 2024-11-07 Seikagaku Kogyo Co Ltd Composición para tratar artropatías y kit que incluye la misma
EP3849522A1 (en) * 2018-09-16 2021-07-21 TLC Biopharmaceuticals, Inc. Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain

Also Published As

Publication number Publication date
EP4192426A1 (en) 2023-06-14
TW202220668A (zh) 2022-06-01
IL300354A (en) 2023-04-01
US20230285293A1 (en) 2023-09-14
JP2023537474A (ja) 2023-09-01
CN116348093A (zh) 2023-06-27
US12514820B2 (en) 2026-01-06
AU2021320774A1 (en) 2023-03-09
WO2022031898A1 (en) 2022-02-10
CA3187955A1 (en) 2022-02-10
CL2023000315A1 (es) 2023-09-22
BR112023001926A2 (pt) 2023-03-07
MX2023001410A (es) 2023-03-06

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20230222

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20240704

Comment text: Request for Examination of Application