CN116348093A - 用于疼痛控制的关节内皮质类固醇的药物组合物 - Google Patents

用于疼痛控制的关节内皮质类固醇的药物组合物 Download PDF

Info

Publication number
CN116348093A
CN116348093A CN202180057600.XA CN202180057600A CN116348093A CN 116348093 A CN116348093 A CN 116348093A CN 202180057600 A CN202180057600 A CN 202180057600A CN 116348093 A CN116348093 A CN 116348093A
Authority
CN
China
Prior art keywords
pharmaceutical composition
intra
pain
osteoarthritis
grade
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180057600.XA
Other languages
English (en)
Chinese (zh)
Inventor
施雪芳
周步朗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiwan Liposome Co Ltd
TLC Biopharmaceuticals Inc
Original Assignee
Taiwan Liposome Co Ltd
TLC Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiwan Liposome Co Ltd, TLC Biopharmaceuticals Inc filed Critical Taiwan Liposome Co Ltd
Publication of CN116348093A publication Critical patent/CN116348093A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN202180057600.XA 2020-08-05 2021-08-05 用于疼痛控制的关节内皮质类固醇的药物组合物 Pending CN116348093A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063061395P 2020-08-05 2020-08-05
US63/061,395 2020-08-05
PCT/US2021/044619 WO2022031898A1 (en) 2020-08-05 2021-08-05 Pharmaceutical composition of intra-articular corticosteroid for pain control

Publications (1)

Publication Number Publication Date
CN116348093A true CN116348093A (zh) 2023-06-27

Family

ID=77519828

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180057600.XA Pending CN116348093A (zh) 2020-08-05 2021-08-05 用于疼痛控制的关节内皮质类固醇的药物组合物

Country Status (13)

Country Link
US (1) US12514820B2 (https=)
EP (1) EP4192426A1 (https=)
JP (1) JP2023537474A (https=)
KR (1) KR20230048066A (https=)
CN (1) CN116348093A (https=)
AU (1) AU2021320774A1 (https=)
BR (1) BR112023001926A2 (https=)
CA (1) CA3187955A1 (https=)
CL (1) CL2023000315A1 (https=)
IL (1) IL300354A (https=)
MX (1) MX2023001410A (https=)
TW (1) TW202220668A (https=)
WO (1) WO2022031898A1 (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2854769T1 (sl) * 2012-07-05 2023-09-29 Taiwan Liposome Company, Ltd. Postopki za zdravljenje artritisa
ES2985871T3 (es) * 2017-03-14 2024-11-07 Seikagaku Kogyo Co Ltd Composición para tratar artropatías y kit que incluye la misma
EP3849522A1 (en) * 2018-09-16 2021-07-21 TLC Biopharmaceuticals, Inc. Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain

Also Published As

Publication number Publication date
EP4192426A1 (en) 2023-06-14
TW202220668A (zh) 2022-06-01
KR20230048066A (ko) 2023-04-10
IL300354A (en) 2023-04-01
US20230285293A1 (en) 2023-09-14
JP2023537474A (ja) 2023-09-01
US12514820B2 (en) 2026-01-06
AU2021320774A1 (en) 2023-03-09
WO2022031898A1 (en) 2022-02-10
CA3187955A1 (en) 2022-02-10
CL2023000315A1 (es) 2023-09-22
BR112023001926A2 (pt) 2023-03-07
MX2023001410A (es) 2023-03-06

Similar Documents

Publication Publication Date Title
US11793755B2 (en) Pharmaceutical composition for intraarticular delivery
CN112702993A (zh) 适用于关节递送的药物组合物及其在治疗关节疼痛中的用途
TW202023529A (zh) 緩釋眼用藥物組合物及其用途
US12514820B2 (en) Pharmaceutical composition of intra-articular corticosteroid for pain control
TWI857961B (zh) 減少關節內類固醇的併發症之方法
HK40087158A (zh) 用於疼痛控制的关节内皮质类固醇的药物组合物
RU2806023C2 (ru) Способы уменьшения осложнений от внутрисуставного стероида
TW202519194A (zh) 用於疼痛控制之關節內皮質類固醇的微脂體組成物
HK40041258A (en) Methods to reduce complications of intra-articular steroid
HK40041739A (en) Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain
HK1219414B (en) Methods of treating arthritis

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40087158

Country of ref document: HK