KR20230044429A - 폐암의 검출을 위한 조성물 및 방법 - Google Patents

폐암의 검출을 위한 조성물 및 방법 Download PDF

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Publication number
KR20230044429A
KR20230044429A KR1020237004288A KR20237004288A KR20230044429A KR 20230044429 A KR20230044429 A KR 20230044429A KR 1020237004288 A KR1020237004288 A KR 1020237004288A KR 20237004288 A KR20237004288 A KR 20237004288A KR 20230044429 A KR20230044429 A KR 20230044429A
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South Korea
Prior art keywords
polypeptide
target
biomarker
lung cancer
rna
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Pending
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KR1020237004288A
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English (en)
Korean (ko)
Inventor
조셉 찰스 세드락
로라 테레사 보톨린
다니엘 파커 살렘
에밀리 수잔 윈-딘
다니엘 구센레이트너
안토니 데이비드 코우빌론
Original Assignee
메르시 바이오애널리틱스, 인코포레이티드
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Publication of KR20230044429A publication Critical patent/KR20230044429A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G01N33/57423—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020237004288A 2020-07-08 2021-07-08 폐암의 검출을 위한 조성물 및 방법 Pending KR20230044429A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063049538P 2020-07-08 2020-07-08
US63/049,538 2020-07-08
PCT/US2021/040971 WO2022011197A1 (en) 2020-07-08 2021-07-08 Compositions and methods for detection of lung cancer

Publications (1)

Publication Number Publication Date
KR20230044429A true KR20230044429A (ko) 2023-04-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237004288A Pending KR20230044429A (ko) 2020-07-08 2021-07-08 폐암의 검출을 위한 조성물 및 방법

Country Status (8)

Country Link
US (1) US20240011993A1 (enExample)
EP (1) EP4179106A4 (enExample)
JP (1) JP2023533970A (enExample)
KR (1) KR20230044429A (enExample)
CN (1) CN116113708A (enExample)
AU (1) AU2021305652A1 (enExample)
CA (1) CA3188377A1 (enExample)
WO (1) WO2022011197A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102752505B1 (ko) * 2024-04-23 2025-01-16 주식회사 이롬 다중오믹스 기반 폐암 진단용 바이오 마커 패널 및 이를 이용한 폐암 진단방법

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12480940B2 (en) 2018-05-17 2025-11-25 Meso Scale Technologies, Llc. Methods for isolating surface marker displaying agents
CN114875144B (zh) * 2022-04-02 2026-04-17 及智(苏州)医学技术有限公司 用于评估肿瘤ibc疗法的疗效的生物标志物、系统、方法及试剂盒
WO2023212315A2 (en) * 2022-04-29 2023-11-02 Meso Scale Technologies, Llc. Methods for detecting and isolating extracellular vesicles
US20240309453A1 (en) * 2023-03-13 2024-09-19 Northwestern University Diagnosis of acute and chronic lung diseases by quantifying spink1 level
CN116855605B (zh) * 2023-06-13 2024-06-25 中国医学科学院北京协和医院 Aoc1作为区分卵巢透明细胞癌和高级别浆液性癌的标志物的应用
CN116593693B (zh) * 2023-07-11 2023-09-19 四川大学华西医院 一种磁性适配体探针、其制备方法和应用及迁移体富集方法
CN117741153A (zh) * 2023-11-07 2024-03-22 南京联笃生物科技有限公司 一种用于多癌种早期筛查、诊断和/或监测的生物标志物及应用
CN118460477B (zh) * 2024-07-09 2024-11-05 苏州唯思尔康科技有限公司 一种特别适于内载有效货物的外泌体支架蛋白及其应用
CN119798401B (zh) * 2024-12-30 2025-10-10 常州因普迈生物科技有限公司 基于pdzk1ip1蛋白的多肽、抗体及其应用
CN120102887B (zh) * 2025-05-10 2025-07-25 浙江格物致知生物科技有限公司 一种检测肺癌的联检产品及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010056337A2 (en) * 2008-11-12 2010-05-20 Caris Mpi, Inc. Methods and systems of using exosomes for determining phenotypes
EP2542696B1 (en) * 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
EP4170031A1 (en) * 2012-10-23 2023-04-26 Caris Science, Inc. Aptamers and uses thereof
AU2013361323B2 (en) * 2012-12-19 2018-09-06 Caris Science, Inc. Compositions and methods for aptamer screening
EP3268476B1 (en) * 2015-03-09 2025-07-16 Caris Science, Inc. Oligonucleotide probes and uses thereof
GB201511546D0 (en) * 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
GB201518655D0 (en) * 2015-10-21 2015-12-02 Olink Ab Method for generating proximity probes
JP7137474B2 (ja) * 2016-03-15 2022-09-14 メルサナ セラピューティクス，インコーポレイティド ＮａＰｉ２ｂ標的化抗体－薬物コンジュゲート及びその使用方法
JP2019168223A (ja) * 2016-08-12 2019-10-03 公立大学法人和歌山県立医科大学 エクソソームの膜に存在するタンパク質の検出方法
EP3740567A4 (en) * 2018-01-18 2022-03-09 Nanosomix Inc. DETECTION OF EXOSOMES AND EXOSOMAL BIOMARKERS FOR DIAGNOSIS AND PROGNOSIS OF DISEASES AND DISORDERS
CN108148912B (zh) * 2018-03-08 2021-10-08 四川大学 肿瘤的生物标志物、应用和肿瘤检测试剂盒
CN110954703A (zh) * 2019-12-27 2020-04-03 杭州迪相实业有限公司 一种同时检测外泌体内蛋白和rna、外泌体膜蛋白的方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102752505B1 (ko) * 2024-04-23 2025-01-16 주식회사 이롬 다중오믹스 기반 폐암 진단용 바이오 마커 패널 및 이를 이용한 폐암 진단방법

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Publication number Publication date
AU2021305652A1 (en) 2023-02-23
EP4179106A4 (en) 2024-10-23
CN116113708A (zh) 2023-05-12
JP2023533970A (ja) 2023-08-07
EP4179106A1 (en) 2023-05-17
CA3188377A1 (en) 2022-01-13
WO2022011197A1 (en) 2022-01-13
US20240011993A1 (en) 2024-01-11

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