KR20230029089A - Microfluidic chip device for measuring microplastics and microplastic measuring method using the same - Google Patents

Abstract

The present invention relates to a microfluidic chip apparatus for measuring microplastics and a microplastics measuring method using the same. The microfluidic chip apparatus for measuring the microplastics according to one technical aspect of the present invention comprises: a supply unit receiving a sample including the microplastics and supplying the sample to a microchannel; and a physical properties measurement unit provided adjacent to the microchannel, and measuring physical properties of the microplastics in the microchannel using an electrode array comprising a plurality of positive electrodes and a plurality of negative electrodes. The physical properties measurement unit may measure the physical properties of the microplastics based on impedances from each of the plurality of positive electrodes to each of the plurality of negative electrodes. Provided are the microfluidic chip apparatus for measuring the microplastics, which can conveniently, immediately and continuously measure the microplastics in various environments, and a microplastics measuring method using the same.

Description

Microfluidic chip device for measuring microplastics and microplastic measuring method using the same {Microfluidic chip device for measuring microplastics and microplastic measuring method using the same}

The present invention relates to a microfluidic chip device for measuring microplastics and a method for measuring microplastics using the same.

With the expansion of plastic use and the emergence of environmental issues, the demand for microplastic measurement technology is increasing.

Most of these microplastics are discharged when absorbed in the body, but toxic substances adsorbed on the surface are accumulated in the body and cause diseases, so there is a need to develop a technology for quantitative detection of the total amount of microplastics and each type of surface toxic substances. .

However, in the conventional case, after obtaining a sample containing microplastics, a separate pretreatment process is essential, and information on microplastics must be individually checked through optical and electron microscopes, etc., and surface adsorbable toxic substances For detection, there is a limitation in that analysis must be additionally performed through a separate analysis system.

Accordingly, there is a growing need for a technology that can conveniently measure microplastics in more diverse environments.

One technical aspect of the present invention is to solve the problems of the prior art, and provides a microfluidic microfluidic chip, that is, based on a Lab-on-a-chip (LOC), for measuring microplastics. Accordingly, it is an object of the present invention to provide a microfluidic chip device for measuring microplastics and a method for measuring microplastics using the microfluidic chip device, which can conveniently, immediately and continuously measure microplastics in various environments.

In addition, one technical aspect of the present invention is a microfluidic chip device for measuring microplastics, which can quickly and accurately derive physical properties such as size, shape, surface area, and number of microplastics using an electrode array, and using the same It is to provide a method for measuring microplastics.

In addition, one technical aspect of the present invention is to measure the toxic properties of microplastics based on optical analysis techniques including spectroscopic techniques, and to quickly and accurately measure the type and total amount of toxic substances in a sample by combining them with physical properties. It is to provide a microfluidic chip device for measuring microplastics and a method for measuring microplastics using the same.

The above objects and various advantages of the present invention will become more apparent from preferred embodiments of the present invention by those skilled in the art.

One technical aspect of the present invention proposes a microfluidic chip device for measuring microplastics. The microfluidic chip device for measuring microplastics receives a sample sample containing microplastics, is provided adjacent to a supply unit providing the microplastics to a microchannel, and is provided adjacent to the microchannel, and includes a plurality of positive electrodes and a plurality of negative electrodes. and a physical property measurement unit for measuring physical properties of the microplastics in the microchannel using an electrode array comprising: The physical property measuring unit may measure physical properties of the microplastics based on impedances from each of the plurality of positive electrodes to each of the plurality of negative electrodes.

In one embodiment, the physical property measuring unit includes a first electrode array including a plurality of positive electrodes formed on one side of the microchannel and a plurality of negative electrodes formed on the other side of the microchannel. It may include an electrode array module including a two-electrode array, and a current control module that conducts current between the plurality of positive electrodes and the plurality of negative electrodes and measures impedance with respect to each current that is passed.

In one embodiment, the physical property measuring unit uses the arrangement structure between the plurality of positive electrodes and the plurality of negative electrodes and the measured impedance, and the microplastics present between the plurality of positive electrodes and the plurality of negative electrodes. It may further include an external measurement module for measuring the physical characteristics of.

In one embodiment, the microchannel may be irradiated with light, and a toxicity characteristic measuring unit configured to measure toxicity characteristics of microplastics present in the microchannel based on optical properties including spectral characteristics of the light may be further included.

In one embodiment, the toxicity characteristic measurement unit includes a light irradiation module for irradiating irradiation light to the microchannel, optical analysis for confirming optical properties including a spectral spectrum for the irradiation light, and the confirmed spectral spectrum Based on the optical characteristics, a toxicity characteristic extraction module for measuring the toxicity characteristics within the microchannel using predetermined optical characteristics and optical characteristic data may be included.

In one embodiment, the physical characteristics may include at least one of size information, number information, surface area information, and shape information of the microplastics. The toxicity characteristic may include at least one of the type and concentration of the toxic substance adsorbed on the microplastic.

Another technical aspect of the present invention proposes a method for measuring microplastics. The method for measuring microplastics is a method for measuring microplastics performed in a microfluidic chip device for measuring microplastics, comprising the steps of inducing a sample containing microplastics into a microchannel and an electrode array provided adjacent to the microchannel. and measuring physical properties of the microplastics in the microchannel by using. The electrode array includes a plurality of positive electrodes formed on one side of the microchannel and a plurality of negative electrodes formed on the other side of the microchannel. Physical properties of the microplastic are measured based on impedances from each of the plurality of positive electrodes to each of the plurality of negative electrodes.

In one embodiment, the measuring of the physical properties of the microplastics may include conducting an electrical current between a plurality of positive electrodes and a plurality of negative electrodes, and measuring impedance for each of the currents that are energized in the conducting step. and measuring physical properties of microplastics existing between the plurality of positive electrodes and the plurality of negative electrodes using the arrangement structure and measured impedance between the plurality of positive electrodes and the plurality of negative electrodes. can do.

In one embodiment, the conducting of the energization may include sequentially applying a voltage between any one positive electrode and a plurality of negative electrodes among a plurality of positive electrodes, and sequentially between any one positive electrode and a plurality of negative electrodes, respectively. An energization step of conducting current and an energization repetition step of sequentially and repeatedly performing the conduction step with respect to the rest of the plurality of positive electrodes.

In one embodiment, the conducting of the energization may include simultaneously applying a voltage between any one positive electrode and a plurality of negative electrodes among a plurality of positive electrodes, and simultaneously applying current between any one positive electrode and a plurality of negative electrodes. and an energization repetition step of sequentially and repeatedly performing the energization step with respect to the rest of the plurality of positive electrodes.

In an embodiment, the method may further include radiating light to the microchannel and measuring toxicity characteristics of microplastics present in the microchannel based on optical properties including spectral characteristics of the light.

In one embodiment, measuring the toxicity characteristics of the microplastics may include irradiating irradiation light to the microchannel, confirming optical properties including a spectral spectrum of the irradiation light, and confirming the spectral spectrum. Based on the optical characteristics including, measuring toxicity characteristics within the microchannel using predetermined optical characteristic data.

The means for solving the problems described above do not enumerate all the features of the present invention. Various means for solving the problems of the present invention will be understood in more detail with reference to specific embodiments of the detailed description below.

According to one embodiment of the present invention, by providing a microplastic measurement environment based on a microfluidic chip, that is, a Lab-on-a-chip (LOC), it is convenient to measure microplastics in various environments. There is an effect that can be performed immediately or continuously.

In addition, according to one embodiment of the present invention, there is an effect of quickly and accurately deriving physical characteristics such as size, shape, surface area, and number of microplastics using an electrode array.

In addition, according to one embodiment of the present invention, there is an effect of measuring the toxic properties of microplastics based on spectroscopic technology and combining them with physical properties to quickly and accurately measure the type and total amount of toxic substances in a sample. there is.

1 is a block diagram illustrating a microfluidic chip device for measuring microplastics according to an embodiment of the present invention.
FIG. 2 is a flowchart illustrating a method for measuring microplastics using the microfluidic chip device shown in FIG. 1 .
FIG. 3 is a block diagram illustrating an embodiment of a physical characteristic measuring unit shown in FIG. 1 .
FIG. 4 is a flowchart illustrating an embodiment of step S1120 shown in FIG. 2 .
5 is a diagram illustrating an electrode array according to an embodiment of the present invention.
6 to 9 are diagrams explaining the derivation of physical properties of microplastics by the physical property measuring unit shown in FIG. 3 .
FIG. 10 is a block diagram illustrating an embodiment of a toxicity characteristic measuring unit shown in FIG. 1 .
FIG. 11 is a flowchart illustrating an embodiment of step S1130 shown in FIG. 2 .

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings.

However, the embodiments of the present invention can be modified in many different forms, and the scope of the present invention is not limited to the embodiments described below. In addition, the embodiments of the present invention are provided to more completely explain the present invention to those skilled in the art.

That is, the above objects, features, and advantages will be described later in detail with reference to the accompanying drawings, and accordingly, those skilled in the art to which the present invention belongs will be able to easily implement the technical spirit of the present invention. In describing the present invention, if it is determined that the detailed description of the known technology related to the present invention may unnecessarily obscure the subject matter of the present invention, the detailed description will be omitted. Hereinafter, preferred embodiments according to the present invention will be described in detail with reference to the accompanying drawings. In the drawings, the same reference numerals are used to indicate the same or similar components.

Also, singular expressions used in this specification include plural expressions unless the context clearly indicates otherwise. In this application, terms such as "consisting of" or "comprising" should not be construed as necessarily including all of the various components or steps described in the specification, and some of the components or some of the steps It should be construed that it may not be included, or may further include additional components or steps.

In addition, in order to describe the system according to the present invention, various components and sub-components thereof are described below. These components and their subcomponents may be implemented in various forms, such as hardware, software, or a combination thereof. For example, each element may be implemented as an electronic configuration for performing a corresponding function, or may be implemented as software itself that can be run in an electronic system or as one functional element of such software. Alternatively, it may be implemented as an electronic configuration and corresponding driving software.

The various techniques described herein may be implemented with hardware or software, or a combination of both where appropriate. As used herein, the terms "Unit", "Server" and "System" likewise refer to a computer-related entity, that is, hardware, a combination of hardware and software, software or It can be treated as equivalent to running software. In addition, each function executed in the system of the present invention may be configured in module units and recorded in one physical memory or distributed between two or more memories and recording media.

Although various flow charts have been disclosed to describe the embodiments of the present invention, these are for convenience of description of each step, and each step is not necessarily performed in the order of the flowchart. That is, each step in the flowchart may be performed simultaneously with each other, in an order according to the flowchart, or in an order reverse to that in the flowchart.

The microfluidics chip device 100 according to an embodiment of the present invention, which will be described below, can receive a sample containing microplastics and calculate physical properties and toxicity characteristics of the microplastics in the sample. there is.

In other words, it is expressed as Lab-on-a-chip (LOC), etc., and can be implemented in a small size and is portable, so it can be used as an on-site analyzer.

In addition, based on its own durability, it can be used as an independent sensor device, for example, a water quality remote monitoring system (TMS) continuous measurement sensor in a water supply and sewage treatment facility.

Hereinafter, the microfluidic chip device 100 for measuring microplastics and a method for measuring microplastics using the microfluidic chip device 100 will be described.

1 is a block diagram illustrating a microfluidic chip device for measuring microplastics according to an embodiment of the present invention, and FIG. 2 illustrates a microfluidic chip measuring method using the microfluidic chip device shown in FIG. 1 It is a sequence of

Referring to FIGS. 1 and 2 , the microfluidic chip device 100 includes a supply unit 110 and a physical characteristic measuring unit 120 . Depending on the embodiment, the microfluidic chip device 100 may further include a toxicity characteristic measuring unit 130 .

The supply unit 110 may receive a sample sample containing microplastic and guide it to a microchannel (S1110).

For example, the supply unit 110 may include a storage module for receiving and storing samples containing microplastics, and may flow the samples stored in the storage module into the microchannel.

The microchannel is a flow path through which a sample containing microplastics flows.

Depending on the embodiment, the microchannel may be configured in various ways. For example, the microchannel may include a plurality of microtubes having different microdiameters and arranged side by side. In this embodiment, by differentially setting the microplastic diameter, the microtube through which the microplastic flows is set differently according to the size of the microplastic in the sample.

The supply unit 110 may include a supply module for allowing a sample to flow into the microchannel. For example, the supply module may open and close a connection between the storage module and the microchannel to allow the sample to flow through the microchannel. Depending on the embodiment, the supply module may include a pump and a valve for inputting the sample into the microchannel and adjusting the input amount.

The physical characteristic measurement unit 120 is provided adjacent to the microchannel. The physical property measurer 120 may measure the physical properties of the microplastics in the microchannel using an electrode array including a plurality of positive electrodes and a plurality of negative electrodes (S1120).

For example, the physical property measurement unit 120 may measure impedances of each of a plurality of negative electrodes from each of a plurality of positive electrodes, and measure physical properties of microplastics based on the measured impedance.

Here, the physical characteristics may include at least one of size information, number information, surface area information, and shape information of the microplastics.

The toxicity characteristic measuring unit 130 may irradiate the microchannel with light and measure the toxicity characteristics of the microplastics present in the microchannel based on optical properties including spectral characteristics of the light (S1130).

Here, the toxicity characteristics may include at least one of the type and concentration of the toxic substance adsorbed on the microplastics.

In addition, the toxicity characteristic measurement unit 130 may generate toxicity information on the entire sample by reflecting the physical characteristics and toxicity characteristics of the microplastics (S1140).

For example, by reflecting the type and amount of toxic substances on the surface of the microplastics measured by the toxicity characteristic measurement unit 130 in information such as the size, shape, surface area, and number of microplastics measured by the physical characteristics measurement unit 120, The type and total amount of toxic substances in the sample can be calculated.

Although not shown, the microfluidic chip device 100 may include a communication module, and may provide data collected through the communication module to other devices such as a server or a manager terminal.

Hereinafter, calculation of physical properties of microplastics using the microfluidic chip device 100 will be described in more detail with reference to FIGS. 3 to 9 .

FIG. 3 is a block diagram illustrating an embodiment of a physical characteristic measuring unit shown in FIG. 1 .

Referring to FIG. 3 , the physical characteristic measurement unit 120 may include an electrode array module 121 , a current control module 122 and an external shape measurement module 123 .

The electrode array module 121 may include a plurality of positive electrodes and a plurality of negative electrodes.

FIG. 5 is a diagram for explaining an electrode array according to an embodiment of the present invention. Referring to FIG. 5, the electrode array module 121 includes a plurality of positive electrodes formed on one side of the microchannel 111. and a second electrode array 121b including a plurality of negative electrodes formed on the other side of the microchannel 111.

The current control module 122 may control operations of the positive and negative electrodes included in the electrode array module 121 so that current flows between the positive and negative electrodes.

For example, the current control module 122 may sequentially apply a voltage between one positive electrode and a plurality of negative electrodes, and control current to sequentially flow between one positive electrode and a plurality of negative electrodes.

As another example, the current control module 122 may simultaneously apply a voltage between one positive electrode and a plurality of negative electrodes, and control current to simultaneously flow between one positive electrode and a plurality of negative electrodes.

In addition, the current control module 122 may measure the impedance of the current energized between the positive electrode and the negative electrode, and provide information about the impedance to the external measurement module 123 .

The external shape measurement module 123 checks information on the arrangement structure between the plurality of positive electrodes and the plurality of negative electrodes, and between the electrode array module 121 based on the arrangement structure and the impedance for the current flowing in each electrode. It is possible to measure the physical properties of microplastics located in

The current control module 122 and the external shape measurement module 123 may include a processor or dedicated control circuit for control processing or arithmetic processing, and may include a storage device such as a memory.

Depending on the embodiment, the current control module 122 and the external shape measuring module 123 may be each function performed by one processor or may be individually implemented.

A physical characteristic measurement method performed by the current control module 122 and the external shape measuring module 123 will be described in more detail with reference to FIG. 4 and the like.

FIG. 4 is a flowchart illustrating an embodiment of S1120 of FIG. 2, which is performed through an embodiment of the physical characteristic measuring unit shown in FIG. 3. Referring to FIG. The example shown in FIG. 4 relates to an embodiment in which a voltage is sequentially applied between one positive electrode and a plurality of negative electrodes to sequentially conduct current, but is not limited thereto, and as described above, one positive electrode A voltage may be simultaneously applied between an electrode and a plurality of negative electrodes so that current is simultaneously conducted.

Referring further to FIG. 4 , the current control module 122 may individually conduct current between a plurality of positive electrodes and a plurality of negative electrodes of the electrode array module 121 .

For example, the current control module 122 sequentially applies a voltage between any one of the plurality of positive electrodes and a plurality of negative electrodes, and sequentially applies a current between any one positive electrode and the plurality of negative electrodes, respectively. can be energized (S1210).

The current control module 122 may measure each impedance in the energized current (S1220). Here, measuring the impedance means including measuring the amount of change in impedance.

Thereafter, the current control module 122 may sequentially and repeatedly perform the above-described energizing step with respect to the remaining of the plurality of positive electrodes (S1230).

The external shape measuring module 123 uses the electrode arrangement structure of the electrode array module 121 - that is, the arrangement structure between the plurality of positive electrodes and the plurality of negative electrodes - and the measured impedance, to measure the plurality of positive electrodes and the plurality of negative electrodes. The physical properties of the microplastics present between the negative electrodes can be measured.

6 to 9 are diagrams for explaining the derivation of physical properties of microplastics by the physical property measuring unit shown in FIG. 3 , which will be further described with reference to them.

In FIG. 6 , the first positive electrode (electrode 1) among the plurality of positive electrodes (electrode 1 to electrode 6) of the first electrode array 121a is a plurality of negative electrodes (electrode A to electrode 6) of the second electrode array 121b. F) and energized respectively.

That is, the current control module 122 may apply a voltage to have a predetermined potential difference between the first positive electrode 1 and the plurality of negative electrodes (electrode A to electrode F), and accordingly, the first positive electrode A current can flow between (1) and the plurality of negative electrodes (electrode A to electrode F).

In one embodiment, the current control module 122 may control the plurality of negative electrodes (electrode A to electrode F) to be sequentially energized one by one. For example, the first positive electrode (electrode 1) and the first negative electrode (electrode A) may be energized, and the impedance change amount may be calculated. Thereafter, the first positive electrode (electrode 1) and the second negative electrode (electrode B) are energized, and an impedance change amount thereto can be calculated.

7 shows that the second positive electrode (electrode 2) of the first electrode array 121a is electrically connected to a plurality of negative electrodes (electrode A to electrode F) of the second electrode array 121b, respectively.

That is, after measuring the impedance of the first positive electrode (electrode 1) and the plurality of negative electrodes (electrode A to electrode F) as shown in FIG. 6, the current control module 122 measures the impedance of the first positive electrode and Current conduction and impedance measurement may be performed in the same manner for another adjacent second positive electrode (electrode 2).

In this way, the current control module 122 may sequentially perform current conduction and impedance measurement between all positive electrodes (electrode 1 to electrode 6) and all negative electrodes (electrode A to electrode F).

An example of the amount of change in impedance between the positive and negative electrodes measured by the current control module 122 is shown in FIG. 8 . In the graph shown in FIG. 8, the x-axis is time and the y-axis is impedance. As shown, the amount of change in impedance varies depending on the relative amount of microplastics located between the two electrodes. That is, the amount of change in impedance between the two electrodes is set differently according to the size and shape of the microplastics. Here, the relative amount of the microplastics may be set to at least one of mass, volume, and density, or a combination thereof.

The current control module 122 may provide the external shape measurement module 123 with information about the impedance, for example, information about a peak value of the amount of change in impedance.

The external shape measurement module 123 can know the electrode arrangement structure of the electrode array module 121 . That is, the arrangement structure and arrangement distance between the plurality of positive electrodes and the plurality of negative electrodes can be known.

The external shape measurement module 123 may derive physical characteristics of the microplastics based on the electrode arrangement structure and the impedance information between the respective electrodes.

For example, the basic physical characteristics (dotted line between two points) of the microplastics derived by the external shape measurement module 123 based on the impedance information shown in FIG. 8 may be as shown in (a) of FIG. 9 . The external shape measurement module 123 may derive the physical properties of the microplastics from the basic physical properties by filling in physical data of a blank area corresponding to the area between each electrode based on the derived basic physical properties.

For example, the shape measurement module 123 may select at least two basic physical characteristics adjacent to the blank area in order to fill the physical property data of the blank area. Then, based on the feature values of the selected at least two basic physical properties, filling of a blank area between the two basic physical properties may be performed. First, a median value of two basic physical characteristics may be set in the middle between the two basic physical characteristics, that is, a median value of a blank area. Thereafter, sequential values may be set in the remaining blank space between the median value and the characteristic value of the basic physical characteristic.

For example, assuming that the feature value of the first physical property is 2 and the feature value of the second physical property is 6, 4 is set as an intermediate value at the center between the first physical property and the second physical property, and the first physical property and the second physical property are A value between 2 and 4 may be set between the center and a value between 4 and 6 may be set between the center and the second physical property.

In this way, if the physical characteristic data is filled in the blank area of Figure (a) of Figure 9, it can be illustrated as Figure (b) of Figure 9.

As described above, the movable chip device 100 for measuring microplastics may obtain information on toxic substances of microplastics using the toxicity characteristic measuring unit 130 .

10 is a block configuration diagram illustrating an embodiment of the toxicity characteristic measurement unit shown in FIG. 1, and FIG. 11 is a flowchart illustrating an embodiment of step S1130 shown in FIG. 2, see FIGS. 10 to 11 and explain this.

On the other hand, the toxicity data extracted by the toxicity characteristic measuring unit is assumed to be due to toxic components attached to microplastics located in the microchannel. This is because it is more common for toxic components to be adsorbed on microplastics rather than existing alone, and even if toxic components can actually exist alone in a sample, it is only a very small amount compared to the amount adsorbed on microplastics. am.

Referring to FIGS. 10 and 11 , the toxic characteristic measurement unit 130 may include a light irradiation module 131 , an optical analysis module 132 , and a toxic characteristic extraction module 133 .

The optical analysis module 132 and the toxicity characteristic extraction module 133 may include a processor or a dedicated control circuit for control processing or arithmetic processing, and may include a storage device such as a memory.

Depending on the embodiment, the optical analysis module 132 and the toxicity characteristic extraction module 133 may be separate functions performed by a single processor or implemented individually.

The light irradiation module 131 may irradiate irradiation light to the microchannel (S1310).

In one embodiment, the light irradiation module 131 may be disposed at a distance greater than or equal to a certain distance from the physical characteristic measurement unit 120 to avoid mutual interference and irradiate irradiation light. To this end, the supply unit 110 controls the flow of the samples existing in the microchannel area corresponding to the physical property measurement unit to the microchannel area corresponding to the toxicity characteristic measurement unit when the physical characteristics measurement is completed. can

The optical analysis module 132 may check the spectral spectrum information of the irradiated light (S1320). Here, the spectral spectrum is

The toxicity characteristic extraction module 133 may measure the toxicity characteristics within the microchannel using pre-set optical characteristic toxicity data based on the confirmed spectral spectrum information (S1330).

For example, the toxicity characteristic extraction module 133 stores an optical characteristic database (optical characteristic toxicity data) including a spectral spectrum characteristic for each hazardous chemical substance, and uses the spectral spectrum provided from the optical analysis module 132 as a group. Comparison with the stored spectral spectrum database can determine which toxic substances are present.

The present invention described above is not limited by the above-described embodiments and the accompanying drawings, but is limited by the claims to be described later, and the configuration of the present invention can be varied within a range that does not deviate from the technical spirit of the present invention. Those skilled in the art can easily know that the present invention can be changed and modified accordingly.

100: microfluidic chip device
110: supply unit
120: physical characteristic measurement unit
121: electrode array module 122: current control module
123: external measurement module
130: toxicity characteristic measuring unit
131: light irradiation module 132: spectroscopy spectrum module
133: toxicity characteristic extraction module

Claims (12)

As a microfluidic chip device,
a supply unit receiving a sample sample containing microplastics and supplying the sample to the microchannel; and
a physical property measurement unit for measuring physical properties of microplastics in the microchannel using an electrode array provided adjacent to the microchannel and including a plurality of positive electrodes and a plurality of negative electrodes;
including,
The physical property measuring unit,
Measuring the physical properties of the microplastic based on the impedance from each of the plurality of positive electrodes to each of the plurality of negative electrodes,
A microfluidic chip device for measuring microplastics.
The method of claim 1, wherein the physical property measurement unit,
an electrode array module including a first electrode array including a plurality of positive electrodes formed on one side of the microchannel and a second electrode array including a plurality of negative electrodes formed on the other side of the microchannel; and
A current control module for conducting current between the plurality of positive electrodes and the plurality of negative electrodes and measuring impedance for each of the energized currents,
A microfluidic chip device for measuring microplastics.
The method of claim 2, wherein the physical property measuring unit,
An appearance measurement module for measuring physical properties of microplastics existing between the plurality of positive electrodes and the plurality of negative electrodes using the arrangement structure and measured impedance between the plurality of positive electrodes and the plurality of negative electrodes including,
A microfluidic chip device for measuring microplastics.
According to claim 1,
Further comprising a toxicity characteristic measuring unit for irradiating light to the microchannel and measuring toxicity characteristics of microplastics present in the microchannel based on optical properties including spectral characteristics thereof,
A microfluidic chip device for measuring microplastics.
The method of claim 4, wherein the toxicity characteristic measurement unit,
a light irradiation module for irradiating irradiation light into the microchannel;
an optical analysis module that checks optical characteristics including spectral characteristics of the irradiation light; and
Based on the optical properties including the confirmed spectral properties, a toxicity property extraction module for measuring the toxicity properties in the microchannel using predetermined optical property toxicity data,
A microfluidic chip device for measuring microplastics.
According to claim 4,
The physical properties are
At least one of size information, number information, surface area information, and shape information of the microplastics,
The toxic properties are
Including at least one of the type and concentration of the toxic substance adsorbed on the microplastic,
A microfluidic chip device for measuring microplastics.
A method for measuring microplastics performed in a microfluidic chip device for measuring microplastics,
guiding a sample containing microplastics into a microchannel; and
measuring physical properties of microplastics in the microchannel using an electrode array provided adjacent to the microchannel;
Including,
The electrode array,
A plurality of positive electrodes formed on one side of the microchannel and a plurality of negative electrodes formed on the other side,
Measuring the physical properties of the microplastic based on the impedance from each of the plurality of positive electrodes to each of the plurality of negative electrodes,
How to measure microplastics.
According to claim 7,
The step of measuring the physical properties of the microplastics,
energization step of conducting current between a plurality of positive electrodes and a plurality of negative electrodes;
measuring impedance for each current energized in the energizing step; and
Measuring physical properties of microplastics present between the plurality of positive electrodes and the plurality of negative electrodes using the arrangement structure and measured impedance between the plurality of positive electrodes and the plurality of negative electrodes,
How to measure microplastics.
According to claim 8,
In the energizing step,
An energization step of sequentially applying a voltage between any one of the plurality of positive electrodes and a plurality of negative electrodes to sequentially pass current between the one positive electrode and the plurality of negative electrodes; and
With respect to the rest of the plurality of positive electrodes, including a energization repetition step of sequentially and repeatedly performing the energization step,
How to measure microplastics.
According to claim 8,
In the energizing step,
an energization step of simultaneously applying a voltage between any one positive electrode of a plurality of positive electrodes and a plurality of negative electrodes to simultaneously conduct current between any one positive electrode and a plurality of negative electrodes; and
With respect to the rest of the plurality of positive electrodes, including a energization repetition step of sequentially and repeatedly performing the energization step,
How to measure microplastics.
According to claim 7,
Irradiating light to the microchannel and measuring toxicity characteristics of microplastics present in the microchannel based on optical properties including spectral characteristics thereof,
How to measure microplastics.
According to claim 11,
Measuring the toxicity characteristics of the microplastics,
irradiating irradiation light to the microchannel;
checking a spectral spectrum of the irradiation light; and
Based on the optical properties including the confirmed spectral properties, measuring toxicity properties in the microchannel using predetermined optical property toxicity data,
How to measure microplastics.

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