KR20220155980A - 항-뮐러 호르몬 폴리펩티드 - Google Patents

항-뮐러 호르몬 폴리펩티드 Download PDF

Info

Publication number
KR20220155980A
KR20220155980A KR1020227018295A KR20227018295A KR20220155980A KR 20220155980 A KR20220155980 A KR 20220155980A KR 1020227018295 A KR1020227018295 A KR 1020227018295A KR 20227018295 A KR20227018295 A KR 20227018295A KR 20220155980 A KR20220155980 A KR 20220155980A
Authority
KR
South Korea
Prior art keywords
gly
ala
amh
leu
cys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020227018295A
Other languages
English (en)
Korean (ko)
Inventor
크레이크 안토니 해리슨
켈리 루이즈 월튼
Original Assignee
모나쉬 유니버시티
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2019904097A external-priority patent/AU2019904097A0/en
Application filed by 모나쉬 유니버시티 filed Critical 모나쉬 유니버시티
Publication of KR20220155980A publication Critical patent/KR20220155980A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/861Adenoviral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
KR1020227018295A 2019-10-30 2020-10-30 항-뮐러 호르몬 폴리펩티드 Ceased KR20220155980A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019904097 2019-10-30
AU2019904097A AU2019904097A0 (en) 2019-10-30 Anti-mullerian hormone polypeptides
PCT/AU2020/051187 WO2021081601A1 (en) 2019-10-30 2020-10-30 Anti-mullerian hormone polypeptides

Publications (1)

Publication Number Publication Date
KR20220155980A true KR20220155980A (ko) 2022-11-24

Family

ID=75714709

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227018295A Ceased KR20220155980A (ko) 2019-10-30 2020-10-30 항-뮐러 호르몬 폴리펩티드

Country Status (8)

Country Link
US (1) US20220411477A1 (enExample)
EP (1) EP4051699A4 (enExample)
JP (1) JP2023501308A (enExample)
KR (1) KR20220155980A (enExample)
CN (1) CN114945588A (enExample)
AU (1) AU2020373165A1 (enExample)
CA (1) CA3156607A1 (enExample)
WO (1) WO2021081601A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025049960A1 (en) * 2023-08-30 2025-03-06 University Of Cincinnati Enhancing the production of anti-mullerian hormone through modification of its prodomain
WO2025085972A1 (en) * 2023-10-27 2025-05-01 Monash University Anti-mullerian hormone agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9289492B2 (en) * 2007-07-17 2016-03-22 The General Hospital Corporation Collecting ovarian cancer stem cells from ovarian cancer cells
WO2010017290A1 (en) * 2008-08-05 2010-02-11 The Trustees Of Columbia University In The City Of New York Müllerian inhibiting substance (mis) analogues
WO2012166712A1 (en) * 2011-05-27 2012-12-06 Fox Chase Cancer Center Rationally-designed anti-mullerian inhibiting substance type ii receptor antibodies
HK1215259A1 (zh) * 2012-11-09 2016-08-19 Ansh Labs Llc 檢測抗苗勒管激素的同種型的抗體組合物及免疫測定方法
WO2017088027A1 (en) * 2015-11-26 2017-06-01 Prince Henry's Institute Of Medical Research Trading As The Hudson Institute Of Medical Research Inhibin analogs
EP3257867A1 (fr) * 2016-06-17 2017-12-20 Biomérieux Procédé de préparation d'anticorps anti-amh et leurs utilisations
US11518793B2 (en) * 2016-12-14 2022-12-06 The General Hospital Corporation Mullerian inhibiting substance (MIS) proteins for ovarian and uterine oncoprotection, and ovarian reserve and uterine preservation
WO2018148649A1 (en) * 2017-02-10 2018-08-16 The Institute For Cancer Research D/B/A Chimera of bone morphogenic protein 2 and the müllerian-inhibiting substance type ii receptor binding region of mullerian-inhibiting substance

Also Published As

Publication number Publication date
EP4051699A1 (en) 2022-09-07
JP2023501308A (ja) 2023-01-18
AU2020373165A1 (en) 2022-05-26
EP4051699A4 (en) 2024-01-17
WO2021081601A1 (en) 2021-05-06
US20220411477A1 (en) 2022-12-29
CN114945588A (zh) 2022-08-26
CA3156607A1 (en) 2021-05-06

Similar Documents

Publication Publication Date Title
KR101993714B1 (ko) 대사 장애를 치료하는데 이용하기 위한 조성물과 방법
AU2022271391A1 (en) Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (LTBP4)
US12544423B2 (en) C3b binding polypeptide
JPH10512440A (ja) サイトカイン”lerk−7”
EP3738977B1 (en) Extracellular domain of alpha subunit of ige fc receptor, pharmaceutical composition comprising same and method for producing same
KR20160048103A (ko) Vegf-c 및 ccbe1의 치료적 용도
US20120322984A1 (en) Methods of reducing trail-induced apoptosis by trail isoforms
KR20220155980A (ko) 항-뮐러 호르몬 폴리펩티드
JP4249927B2 (ja) コラーゲン様新規蛋白clacおよびその前駆体、ならびにそれらをコードする遺伝子
EP1410802A1 (en) Cell death inducers for mast cells
JP2024525221A (ja) アルツハイマー病を治療するためのsorlaミニ受容体
EP4538370A1 (en) Fusion protein containing truncated iga protease and use thereof
WO2018154584A1 (en) Chimeras of soluble dr3 and pro-tace domain and use thereof
WO2025085972A1 (en) Anti-mullerian hormone agonists
EP2706113B1 (en) Synthetic peptide capable of inducing expression of type-2 tnf receptor and use thereof
JP2000125888A (ja) シアロアドヘシンファミリ―メンバ――3
JP4346540B2 (ja) 絨毛外栄養膜細胞特異的蛋白質
US11136368B2 (en) Cancer treatment using CX26 blocking peptides
US20100168386A1 (en) Fusion protein carrying neurotrophin across the blood-brain barrier, encoding gene and uses thereof
JP2008161074A (ja) caveolin−1−Fcγ1融合タンパク質及びその使用
JPWO1997042319A1 (ja) 新規Fas抗原誘導体
KR20140121088A (ko) 신규한 소포체 막투과성 단백질

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

B15 Application refused following examination

Free format text: ST27 STATUS EVENT CODE: N-2-6-B10-B15-EXM-PE0601 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601