KR20220114629A - 미코박테리아 감염을 치료하기 위한 아목시실린 및 아비박탐 유도체의 경구 투여 조합 - Google Patents

미코박테리아 감염을 치료하기 위한 아목시실린 및 아비박탐 유도체의 경구 투여 조합 Download PDF

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Publication number
KR20220114629A
KR20220114629A KR1020227024569A KR20227024569A KR20220114629A KR 20220114629 A KR20220114629 A KR 20220114629A KR 1020227024569 A KR1020227024569 A KR 1020227024569A KR 20227024569 A KR20227024569 A KR 20227024569A KR 20220114629 A KR20220114629 A KR 20220114629A
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KR
South Korea
Prior art keywords
substituted
oxy
abibactam
pharmaceutically acceptable
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020227024569A
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English (en)
Korean (ko)
Inventor
요아킴 트리아스
Original Assignee
아릭사 파마슈티컬스 인코포레이티드
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Application filed by 아릭사 파마슈티컬스 인코포레이티드 filed Critical 아릭사 파마슈티컬스 인코포레이티드
Publication of KR20220114629A publication Critical patent/KR20220114629A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227024569A 2019-12-20 2020-12-17 미코박테리아 감염을 치료하기 위한 아목시실린 및 아비박탐 유도체의 경구 투여 조합 Withdrawn KR20220114629A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962951187P 2019-12-20 2019-12-20
US62/951,187 2019-12-20
PCT/IB2020/062099 WO2021124191A1 (en) 2019-12-20 2020-12-17 Orally administered combinations of amoxicillin and avibactam derivatives for treating mycobacterial infections

Publications (1)

Publication Number Publication Date
KR20220114629A true KR20220114629A (ko) 2022-08-17

Family

ID=73856245

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227024569A Withdrawn KR20220114629A (ko) 2019-12-20 2020-12-17 미코박테리아 감염을 치료하기 위한 아목시실린 및 아비박탐 유도체의 경구 투여 조합

Country Status (8)

Country Link
US (2) US20210186983A1 (https=)
EP (1) EP4076451A1 (https=)
JP (2) JP2021102605A (https=)
KR (1) KR20220114629A (https=)
CN (1) CN115003302A (https=)
AU (1) AU2020405540A1 (https=)
CA (1) CA3164938A1 (https=)
WO (1) WO2021124191A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119841826B (zh) * 2024-09-30 2026-04-10 科睿迪(南京)医药科技有限公司 二氮杂二环类β-内酰胺酶抑制剂及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10085999B1 (en) * 2017-05-10 2018-10-02 Arixa Pharmaceuticals, Inc. Beta-lactamase inhibitors and uses thereof
JP2022524118A (ja) * 2019-03-12 2022-04-27 アリクサ ファーマシューティカルズ、インコーポレイテッド アビバクタム誘導体の結晶形

Also Published As

Publication number Publication date
US20240245705A1 (en) 2024-07-25
EP4076451A1 (en) 2022-10-26
WO2021124191A1 (en) 2021-06-24
US20210186983A1 (en) 2021-06-24
AU2020405540A1 (en) 2022-06-09
CN115003302A (zh) 2022-09-02
JP2021102605A (ja) 2021-07-15
CA3164938A1 (en) 2021-06-24
JP2025163188A (ja) 2025-10-28

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Legal Events

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A201 Request for examination
PA0105 International application

Patent event date: 20220715

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20220715

Comment text: Request for Examination of Application

PG1501 Laying open of application
PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20240715

WITB Written withdrawal of application