KR20220091242A - Composition for improving skin wrinkles and cosmetic composition comprising the same - Google Patents

Abstract

The present invention relates to a composition for improving skin wrinkles and a cosmetic composition comprising the same. A composition for improving skin wrinkles according to an embodiment of the present invention comprises: Echo extract; Bupyeongcho extract; It may include any one selected from the group consisting of Centella asiatica extract and mixtures thereof. The composition for improving skin wrinkles of the present invention can prevent and improve skin aging and skin wrinkles by increasing the skin moisturizing effect and environmental resistance along with the antioxidant effect.

Description

A composition for improving skin wrinkles and a cosmetic composition comprising the same

The present invention relates to a composition for improving skin wrinkles and a cosmetic composition comprising the same. More specifically, it inhibits oxidation to prevent damage and aging of skin cells, and promotes antioxidant activity such as protecting cells from harmful oxidizing substances in the body, and improves skin moisture and environmental resistance to prevent skin wrinkles and improve skin wrinkles A composition capable of exhibiting activity and a cosmetic composition using the same are provided.

Skin aging, one of human aging phenomena, is largely divided into internal and external factors as the cause. Among them, UV irradiation by sunlight as an external factor is known as the main cause of physiological and morphological changes in skin aging. . Ultraviolet rays, which have a direct effect on the skin, penetrate deeply into the epidermis and dermis of the skin and undergo various processes including several enzymatic reactions to generate oxygen free radicals in cells and tissues. When it is created, mutations, inflammation, cell death, carcinogenesis, and skin aging appear. In the skin, active oxygen attacks the cell membrane and oxidizes it, and the cell membrane is damaged by the oxidized lipid, resulting in loss of normal skin cell function. In addition, the balance of the skin's antioxidant defense system is disturbed, and the skin cannot recover from the continuous oxidation state.

In addition, an increase in collagen-degrading enzymes is one of the important causes of degeneration and destruction of collagen fibers, and active oxygen generated in vivo inhibits the activation of collagenases such as matrix metalloproteinases (MMPs).

It promotes and inhibits the synthesis of collagen, thereby reducing the elasticity of the skin and promoting the creation of wrinkles.

MMPs (Matrix metalloproteinases) are a group of enzymes involved in the decomposition of the extracellular matrix (ECM) and basement membrane. Depending on their structure and functional properties, interstitial collagenase, stromelysin, gelatinase (gelatinase), membrane-type MMP (membrane-type MMP, MT-MMP) is divided into four subfamily (subfamily). More than 20 types of MMPs are known from various species such as mammals, birds, amphibians, plants and nematodes.

In addition, although MMPs differ from each other in substrate specificity, they have structural and functional similarities. Therefore, the names of all MMPs are generally numbered. That is, collagenase-1, 2, 3 to MMP-1, 8, 13, gelatinase-A, B to MMP-2, 9, stromelysin-1, 2, 3 to MMP-3, 10, 11, metalloelastase to MMP-12, matrilysin to MMP-7, membrane-type MMP (MT-MMPs) to MMP-14, 15, 16,17 , 24, enamellysin is called MMP-20, MMP-19, MMP-23, etc.

Each of these enzymes can degrade proteins such as corresponding substrates, ie, collagen, fibronectin, laminin, proteoglycan, entactin, and elastin. MMP is a metalloproteinase having zinc in its active center and is secreted in the form of an inactive precursor (zymogen) in vivo. In order to have enzymatic activity, structural modification occurs and the amino terminal site must be cleaved, and the activated MMP activity is regulated by inhibitors such as 2-macroglobulin or TIMPs (Tissue inhibitors of metalloproteinase). The majority of cells, including keratinocytes and fibroblasts, secrete MMPs. Since MMP activity in the skin increases and collagen can be remarkably reduced even during a single UV irradiation, MMP has been reported as a major factor in photoaging.

Until now, the most effective method for wrinkle improvement is a method using retinol and retinoic acid. The wrinkle improvement or elasticity improvement effect of retinoids such as retinol and retinoic acid is well known through the literature (Dermatology therapy, 1998, 16, 357~364). However, these retinoids have positive effects such as wrinkle improvement or elasticity improvement, and have the disadvantage that irritation appears even when only a small amount is applied to the skin. . Therefore, research to stabilize the retinoid is continuously being conducted, but the problem of irritation to the skin, that is, the safety problem, has not been solved yet.

What has been suggested as a substitute for this is to inhibit the activity of enzymes that decompose collagen and elastin, and studies on inhibitors capable of inhibiting the activity of these enzymes are being actively conducted. Recently, as the marked increase in the activity of collagenase and matrix metalloprotease, which are enzymes capable of decomposing collagen, has been revealed as one of the factors for generating skin wrinkles, interest is increasing as a target for improving skin wrinkles.

On the other hand, recently, much attention has been paid to functional cosmetics having functions such as wrinkle relief and whitening obtained from natural extracts to reduce skin irritation caused by various chemicals. Natural ingredients have fewer side effects on the skin, and as consumers' response to external skin preparations using natural ingredients increases, the value of development as a raw material for photoaging prevention cosmetic compositions is further increasing. For example, Japanese Patent Application Laid-Open No. Hei 9-672662 describes seaweed extracts having hyaluronidase inhibitory effects. Japanese Patent Laid-Open No. 10-85905 describes the skin texture improvement effect of fucoidan extracted from Wakame. Japanese Patent Laid-Open No. 2-245087 describes the antioxidant effect of an extract of the genus Sargassum. Japanese Patent Laid-Open No. 3-294384 discloses an antioxidant composition extracted from the genus Hizikia. Japanese Patent Laid-Open No. 7-10769 describes an extract of Phaeophyceae having an astringent effect. U.S. Patent No. 5,508,033 describes a cosmetic with anti-radical activity, including mother and child. Domestic Patent No. 810134 discloses the steps of washing and desalting the mother-of-pearl or shiitake; endo-β1,4-glucanase, alginic acid lyase (Alginic acid lyase) and exocellulose (exocellulose) consisting of a primary enzymatic digestion; And arabanase (Arabanase), cellulase, and β 1,4-glucanase, characterized in that it comprises a series of steps for decomposing the secondary enzyme consisting of an enzymatic decomposition product of mother-of-pearl or Hibiscus, and a method for producing the same, , it is disclosed that it can be used as a cosmetic or the like.

KR 10-0810134 B1 KR 10-2013-0023326 A

An object of the present invention is to prevent skin aging by exhibiting an antioxidant effect, and to prevent and improve skin wrinkles.

An object of the present invention is to prevent and improve skin wrinkles by increasing skin resistance and moisturizing activity.

It is an object of the present invention to provide a composition for preventing and improving skin wrinkles that can solve problems such as side effects due to long-term use by using a raw material derived from a natural product.

It is an object of the present invention to provide cosmetics of various formulations through a functional cosmetic composition for skin wrinkle improvement comprising the composition.

In order to achieve the above object, the composition for skin wrinkle improvement according to an embodiment of the present invention is Eoseongcho extract; Bupyeongcho extract; It may include any one selected from the group consisting of Centella asiatica extract and mixtures thereof.

The extract may be one selected from water, alcohols having 1 to 10 carbon atoms, and mixtures thereof with a solvent.

The composition for improving skin wrinkles has antioxidant activity; It may be to show the effect of improving skin aging and improving skin wrinkles.

When the composition according to the present invention exhibits an antioxidant effect, it is possible to prevent skin aging and prevent and improve skin wrinkles.

When the composition according to the present invention increases skin resistance and moisturizing activity, it is possible to prevent and improve skin wrinkles.

The present invention provides a composition for preventing and improving skin wrinkles by using a raw material derived from a natural product to solve problems such as side effects due to long-term use.

The present invention provides cosmetics of various formulations through a functional cosmetic composition for improving skin wrinkles comprising the composition.

In the case of the composition, it is possible to prevent aging due to oxidative stress by inhibiting free radicals through excellent antioxidant activity. In addition, while increasing the environmental resistance of the skin, it is possible to effectively prevent and alleviate skin wrinkles through an excellent moisturizing effect.

The Eoseongcho (Houttuynia cordata) is also called Yakmomil, and the name Houttuynia cordata is given because the leaves emit a fishy smell. It shows the same vigorous fertility as weeds, and is mainly eaten as tea.

The Bupyeongcho (Spirodela polyrhiza) refers to an annual floating aquatic plant belonging to the family Lepidoptera. Donga (冬芽) born from the mother in autumn sinks into the water, overwinters, and rises to the surface again the following year to reproduce.

Centella asiatica is a perennial herb commonly found in the mountains or fields of the southern islands of the Korean Peninsula. The main stem extends sideways, and there are two degenerated scale-shaped leaves near the node where the root takes place, the leaves are dense at the node, elongate, 2 to 5cm in diameter, the surface is glossy, and the edge has dull sawtooth. , the length of the petiole is 4 to 20 cm.

Preferably, the composition may include a Bupyeongcho extract. In the case of a single extract, when the Bupyeongcho extract is used, antioxidant and skin wrinkle improvement activity may be more excellent.

Preferably, the composition comprises eoseongcho extract; Bupyeongcho extract; Centella asiatica extract may be mixed. In the case of mixing each extract, a synergistic effect may appear depending on the interaction of the active ingredients and the difference in the active ingredients contained in each extract.

More preferably, the composition includes a Bupyeongcho extract, and 30 to 80 parts by weight of an eoseongcho extract based on 100 parts by weight of the Bupyeongcho extract; 60 to 120 parts by weight of Centella asiatica extract may be mixed. According to the above range, antioxidant activity and skin wrinkle improvement activity may be more excellent.

The composition comprises 1 to 10 parts by weight of peppermint extract based on 100 parts by weight of the Bupyeongcho extract; Apple mint 5 to 20 parts by weight; 1 to 10 parts by weight of sage and 5 to 20 parts by weight of basil extract may be further included. In the case of the composition, skin irritation may be lowered, and anti-aging, skin wrinkle improvement effects and antioxidant activity may be higher.

The cosmetic composition of the present invention may be prepared in any formulation conventionally prepared in the art, for example, a solution, suspension, paste, gel, cream, lotion, powder, soap, surfactant-containing clenosis, oil , powder foundation, emulsion foundation, wax foundation, and spray may be formulated, but are not limited thereto. More specifically, flexible lotion, nourishing lotion, nourishing cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray or powder formulation, oil-in-water (O/W) type or water-in-oil It may be prepared as a (W/O) type formulation or ointment.

In addition, functional substances such as whitening agents, moisturizing agents, anti-inflammatory agents, antibacterial agents, antifungal agents, vitamins, sunscreen agents, antibiotics, anti-acne agents, perfumes, and dyes may be included, if necessary, in an amount conventionally used in the cosmetic field. It may be included in the cosmetic composition according to the present invention.

The cosmetic composition according to another embodiment of the present invention is prepared by including the composition for skin regeneration and skin moisturizing as an active ingredient.

The regenerating cream according to another embodiment of the present invention is prepared by including the cosmetic composition as an active ingredient.

A moisturizing cream according to another embodiment of the present invention is prepared by including the cosmetic composition as an active ingredient.

The dermatologically acceptable carrier includes purified water, oil, wax, fatty acid, fatty acid alcohol, fatty acid ester, surfactant, moisture absorbent, thickener, antioxidant, viscosity stabilizer, chelating agent, buffer, preservative, lower alcohol, etc. However, the present invention is not limited thereto, and the types and concentrations thereof vary, and include parts that those skilled in the art can change within the scope of the present invention.

Cosmetics prepared from the cosmetic composition of the present invention can be prepared in the form of general emulsified formulations and solubilized formulations. Cosmetics in emulsified formulations include nutritional lotions, creams, and essences, and solubilized cosmetics include softening lotions.

The cosmetic may be prepared in the form of an adjuvant that can be applied topically or systemically commonly used in the art by containing a dermatologically acceptable medium or base in addition to the extract of the present invention.

Suitable cosmetic formulations include, for example, solutions, gels, solid or kneaded dry products, emulsions obtained by dispersing an oil phase in an aqueous phase, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes), non-ionic It may be provided in the form of a vesicular dispersant, cream, skin, lotion, powder, ointment, spray or in the form of a cone stick. In addition, it may be prepared in the form of a foam or an aerosol composition further containing a compressed propellant.

Products to which the cosmetic composition of the present invention can be added include, for example, cosmetics such as astringent lotion, softening lotion, nutrient lotion, various creams, essence, pack, foundation, etc. and cleansing, face wash, soap, treatment or liquid cosmetics etc. Specific formulations include skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream, moisture cream, hand cream, essence, nourishing essence, pack, soap, shampoo, cleansing foam. , cleansing lotion, cleansing cream, body lotion, body cleanser, emulsion, press powder, loose powder or eye shadow formulations.

Although preferred embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and various modifications and improvements by those skilled in the art using the basic concept of the present invention as defined in the following claims are also provided. is within the scope of the

Claims (3)

Eoseongcho extract; Bupyeongcho extract; containing any one selected from the group consisting of Centella asiatica extract and mixtures thereof
A composition for improving skin wrinkles. The method of claim 1,
The extract is one selected from water, alcohols having 1 to 10 carbon atoms, and mixtures thereof with a solvent
A composition for improving skin wrinkles. A cosmetic for improving skin wrinkles comprising the composition according to claim 1 or 2.