KR20220024495A - 종양용해성 아데노바이러스 및 체크포인트 억제제 조합 요법 - Google Patents

종양용해성 아데노바이러스 및 체크포인트 억제제 조합 요법 Download PDF

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KR20220024495A
KR20220024495A KR1020227000995A KR20227000995A KR20220024495A KR 20220024495 A KR20220024495 A KR 20220024495A KR 1020227000995 A KR1020227000995 A KR 1020227000995A KR 20227000995 A KR20227000995 A KR 20227000995A KR 20220024495 A KR20220024495 A KR 20220024495A
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cancer
transgene
tnfalpha
adenoviral vector
checkpoint inhibitor
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Korean (ko)
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악셀리 헴민키
아이노 칼레르보
빅토르 세르베라-카라스콘
리카 하부넨
호아오 비에이라 로우렌코 도스 산토스
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틸트 바이오세러퓨틱스 오이
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    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
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KR1020227000995A 2019-06-14 2020-06-12 종양용해성 아데노바이러스 및 체크포인트 억제제 조합 요법 Pending KR20220024495A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962861339P 2019-06-14 2019-06-14
US62/861,339 2019-06-14
US202062988422P 2020-03-12 2020-03-12
US62/988,422 2020-03-12
PCT/FI2020/050422 WO2020249873A1 (en) 2019-06-14 2020-06-12 Oncolytic adenovirus and checkpoint inhibitor combination therapy

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KR20220024495A true KR20220024495A (ko) 2022-03-03

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US (1) US20220251604A1 (https=)
EP (1) EP3983004A1 (https=)
JP (2) JP2022536929A (https=)
KR (1) KR20220024495A (https=)
CN (1) CN113924117A (https=)
AU (1) AU2020292610A1 (https=)
BR (1) BR112021025031A2 (https=)
CA (1) CA3138834A1 (https=)
SG (1) SG11202111820PA (https=)
WO (1) WO2020249873A1 (https=)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
WO2022170919A1 (zh) * 2021-02-09 2022-08-18 南京惟亚德生物医药有限公司 一种重组溶瘤腺病毒及其应用
CN118055776A (zh) 2021-10-04 2024-05-17 蒂尔坦生物制药有限公司 编码白细胞介素-7(il-7)多肽的溶瘤病毒载体
KR20250158053A (ko) * 2023-03-01 2025-11-05 틸트 바이오세러퓨틱스 오이 종양용해성 아데노바이러스 벡터의 새로운 투여 요법
WO2024207425A1 (en) * 2023-04-07 2024-10-10 Virogin Biotech (Shanghai) Ltd. Combination of recombinant oncolytic virus and checkpoint inhibitor for the treatment of cancer
CN120835927A (zh) * 2023-09-28 2025-10-24 复旦大学附属华山医院 用于治疗胶质瘤的组合物
JP7816735B2 (ja) * 2024-01-22 2026-02-18 国立大学法人 鹿児島大学 腫瘍溶解性ウイルス及びそれを用いたがん治療

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101899114A (zh) 2002-12-23 2010-12-01 惠氏公司 抗pd-1抗体及其用途
DK2439273T3 (da) 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
BR122017025062B8 (pt) 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
DK2986311T3 (en) 2013-04-18 2019-02-25 Tilt Biotherapeutics Oy IMPROVED ADOPTIVE CELL THERAPY

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JP2025138703A (ja) 2025-09-25
CA3138834A1 (en) 2020-12-17
AU2020292610A1 (en) 2021-11-18
BR112021025031A2 (pt) 2022-01-25
US20220251604A1 (en) 2022-08-11
EP3983004A1 (en) 2022-04-20
CN113924117A (zh) 2022-01-11
JP2022536929A (ja) 2022-08-22
WO2020249873A1 (en) 2020-12-17
SG11202111820PA (en) 2021-11-29

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