KR20210149090A - 세포 면역요법을 향상시키기 위한 방법 - Google Patents

세포 면역요법을 향상시키기 위한 방법 Download PDF

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KR20210149090A
KR20210149090A KR1020217034537A KR20217034537A KR20210149090A KR 20210149090 A KR20210149090 A KR 20210149090A KR 1020217034537 A KR1020217034537 A KR 1020217034537A KR 20217034537 A KR20217034537 A KR 20217034537A KR 20210149090 A KR20210149090 A KR 20210149090A
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cells
car
cell
cancer
mpba
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안토니오 마리오 케리도 마르콘데스
피터 베네딕트 커크
다카히로 미야자키
카메론 제이 터틀
스탠리 알 리들
캐시 케이 처우
지몬 피 프레쓸레
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넥타르 테라퓨틱스
프레드 헛친슨 켄서 리서치 센터
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
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    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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KR1020217034537A 2019-04-05 2020-04-04 세포 면역요법을 향상시키기 위한 방법 Pending KR20210149090A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962830212P 2019-04-05 2019-04-05
US62/830,212 2019-04-05
US201962861858P 2019-06-14 2019-06-14
US62/861,858 2019-06-14
US201962898473P 2019-09-10 2019-09-10
US62/898,473 2019-09-10
US201962944955P 2019-12-06 2019-12-06
US62/944,955 2019-12-06
PCT/US2020/026778 WO2020206395A1 (en) 2019-04-05 2020-04-04 Method for enhancing cellular immunotherapy

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KR20210149090A true KR20210149090A (ko) 2021-12-08

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US (1) US20230158164A1 (https=)
EP (1) EP3946426A4 (https=)
JP (2) JP7672342B2 (https=)
KR (1) KR20210149090A (https=)
CN (1) CN113677362A (https=)
AU (1) AU2020252569B2 (https=)
CA (1) CA3134539A1 (https=)
IL (1) IL286971A (https=)
MX (1) MX2021012236A (https=)
WO (1) WO2020206395A1 (https=)

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EP4463135A2 (en) 2022-01-10 2024-11-20 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023193015A1 (en) 2022-04-01 2023-10-05 Sana Biotechnology, Inc. Cytokine receptor agonist and viral vector combination therapies
WO2024215987A1 (en) * 2023-04-14 2024-10-17 Sotio Biotech Inc. IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
EP4694916A1 (en) * 2023-04-14 2026-02-18 SOTIO Biotech Inc. Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
WO2025191133A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Il-21 muteins, fusion proteins comprising the same and uses thereof
WO2025191136A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof
WO2025264864A1 (en) * 2024-06-18 2025-12-26 Fred Hutchinson Cancer Center Human anti-cd45 antibodies and uses thereof

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EP3568474A1 (en) 2017-01-10 2019-11-20 Intrexon Corporation Modulating expression of polypeptides via new gene switch expression systems
CN108728459B (zh) 2017-04-24 2023-08-04 上海恒润达生生物科技股份有限公司 靶向cd19的嵌合抗原受体并联合表达il-15的方法和用途
IL270634B2 (en) * 2017-05-15 2025-06-01 Nektar Therapeutics Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods
US12350312B2 (en) * 2017-09-06 2025-07-08 Fred Hutchinson Cancer Center Methods for improving adoptive cell therapy

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WO2020206395A1 (en) 2020-10-08
MX2021012236A (es) 2021-11-04
AU2020252569B2 (en) 2026-02-05
JP7672342B2 (ja) 2025-05-07
EP3946426A1 (en) 2022-02-09
IL286971A (en) 2021-12-01
JP2022526408A (ja) 2022-05-24
AU2020252569A1 (en) 2021-11-04
EP3946426A4 (en) 2023-01-04
US20230158164A1 (en) 2023-05-25
JP2025089477A (ja) 2025-06-12
CA3134539A1 (en) 2020-10-08
CN113677362A (zh) 2021-11-19

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