KR20210135261A - 인플루엔자 ha 스플릿 백신의 제조 방법 - Google Patents

인플루엔자 ha 스플릿 백신의 제조 방법 Download PDF

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Publication number
KR20210135261A
KR20210135261A KR1020217030986A KR20217030986A KR20210135261A KR 20210135261 A KR20210135261 A KR 20210135261A KR 1020217030986 A KR1020217030986 A KR 1020217030986A KR 20217030986 A KR20217030986 A KR 20217030986A KR 20210135261 A KR20210135261 A KR 20210135261A
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KR
South Korea
Prior art keywords
influenza
split vaccine
vaccine
split
antibody
Prior art date
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Pending
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KR1020217030986A
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English (en)
Korean (ko)
Inventor
요시마사 다카하시
유 아다치
마나부 아토
Original Assignee
국립감염증연구소장이 대표하는 일본국
다이닛본 스미토모 세이야꾸 가부시끼가이샤
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Application filed by 국립감염증연구소장이 대표하는 일본국, 다이닛본 스미토모 세이야꾸 가부시끼가이샤 filed Critical 국립감염증연구소장이 대표하는 일본국
Publication of KR20210135261A publication Critical patent/KR20210135261A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
KR1020217030986A 2019-03-04 2020-03-03 인플루엔자 ha 스플릿 백신의 제조 방법 Pending KR20210135261A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019038662 2019-03-04
JPJP-P-2019-038662 2019-03-04
PCT/JP2020/008974 WO2020179797A1 (ja) 2019-03-04 2020-03-03 インフルエンザhaスプリットワクチンの製造方法

Publications (1)

Publication Number Publication Date
KR20210135261A true KR20210135261A (ko) 2021-11-12

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217030986A Pending KR20210135261A (ko) 2019-03-04 2020-03-03 인플루엔자 ha 스플릿 백신의 제조 방법

Country Status (14)

Country Link
US (1) US20220152191A1 (en, 2012)
EP (1) EP3936147A4 (en, 2012)
JP (1) JP7545955B2 (en, 2012)
KR (1) KR20210135261A (en, 2012)
CN (1) CN114096273A (en, 2012)
AU (1) AU2020233456A1 (en, 2012)
BR (1) BR112021017310A8 (en, 2012)
CA (1) CA3132578A1 (en, 2012)
EA (1) EA202192398A1 (en, 2012)
IL (1) IL285984A (en, 2012)
MX (1) MX2021010685A (en, 2012)
PH (1) PH12021552094A1 (en, 2012)
SG (1) SG11202109566XA (en, 2012)
WO (1) WO2020179797A1 (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12021550175A1 (en) 2018-07-23 2022-07-11 Japan As Represented By Director General Of Nat Institute Of Infectious Diseases Composition containing influenza vaccine
CN114929270A (zh) * 2019-11-07 2022-08-19 塞其里斯英国有限公司 用于生产具有减小的颗粒大小的病毒疫苗的组合物和方法
WO2024225404A1 (ja) * 2023-04-26 2024-10-31 国立感染症研究所長が代表する日本国 抗インフルエンザ抗体

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516090A (ja) 2013-03-29 2016-06-02 セルトリオン・インコーポレイテッド 2以上のインフルエンザaウイルス中和結合分子を含む組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2374894B1 (en) * 1993-09-13 2014-09-17 Protein Sciences Corporation A method for producing influenza hemagglutinin multivalent vaccines
US20230201329A1 (en) * 2006-07-17 2023-06-29 Glaxosmithkline Biologicals Sa Influenza vaccine
US20090181078A1 (en) * 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
PE20090146A1 (es) * 2007-04-20 2009-03-23 Glaxosmithkline Biolog Sa Composicion inmunogenica contra el virus influenza
CA2744354C (en) * 2008-11-25 2018-10-02 Avir Green Hills Biotechnology Research Development Trade Ag Method for production of ph stable enveloped viruses
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗
CN104302317B (zh) * 2012-05-16 2016-07-06 Kj生物科学有限公司 新型和改进的流感疫苗
WO2016178811A1 (en) * 2015-05-04 2016-11-10 Epivax, Inc. Modified h7 hemagluttinin glycoprotein of the influenza a/shanghai/2/2013 h7 sequence
ES2805724T3 (es) * 2015-09-29 2021-02-15 Sumitomo Dainippon Pharma Co Ltd Compuestos de adenina conjugados y su uso como adyuvantes de vacunas
CN110650729B (zh) * 2017-03-29 2024-08-20 住友制药株式会社 疫苗佐剂制剂
JP7403733B2 (ja) * 2017-09-04 2023-12-25 国立感染症研究所長 インフルエンザhaスプリットワクチンの製造方法
PH12021550175A1 (en) * 2018-07-23 2022-07-11 Japan As Represented By Director General Of Nat Institute Of Infectious Diseases Composition containing influenza vaccine
CA3121613A1 (en) * 2018-12-26 2020-07-02 Sumitomo Dainippon Pharma Co., Ltd. Preparation including vaccine adjuvant
BR112021017074A2 (pt) * 2019-02-28 2021-11-09 Novavax Inc Métodos para prevenir doença ou distúrbio causado(a) por infecção por rsv

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516090A (ja) 2013-03-29 2016-06-02 セルトリオン・インコーポレイテッド 2以上のインフルエンザaウイルス中和結合分子を含む組成物

Also Published As

Publication number Publication date
BR112021017310A2 (en, 2012) 2021-11-16
IL285984A (en) 2021-10-31
PH12021552094A1 (en) 2022-05-30
AU2020233456A1 (en) 2021-10-07
EP3936147A4 (en) 2022-09-28
WO2020179797A1 (ja) 2020-09-10
MX2021010685A (es) 2021-12-10
BR112021017310A8 (pt) 2022-12-06
US20220152191A1 (en) 2022-05-19
EA202192398A1 (ru) 2021-11-23
JP7545955B2 (ja) 2024-09-05
EP3936147A1 (en) 2022-01-12
JPWO2020179797A1 (en, 2012) 2020-09-10
CN114096273A (zh) 2022-02-25
SG11202109566XA (en) 2021-10-28
CA3132578A1 (en) 2020-09-10

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PA0105 International application

Patent event date: 20210927

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application