KR20210107719A - 자궁내막증과 연관된 미토콘드리아 dna 결실 - Google Patents

자궁내막증과 연관된 미토콘드리아 dna 결실 Download PDF

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Publication number
KR20210107719A
KR20210107719A KR1020217022010A KR20217022010A KR20210107719A KR 20210107719 A KR20210107719 A KR 20210107719A KR 1020217022010 A KR1020217022010 A KR 1020217022010A KR 20217022010 A KR20217022010 A KR 20217022010A KR 20210107719 A KR20210107719 A KR 20210107719A
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South Korea
Prior art keywords
nucleotide
nucleotides
mtdna
deletion
seq
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KR1020217022010A
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English (en)
Korean (ko)
Inventor
제니퍼 크리드
안드레아 매그라
브라이언 레걸리
앤드류 하보틀
로버트 어셔
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엠디엔에이 라이프 사이언시즈 인코퍼레이티드
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Publication of KR20210107719A publication Critical patent/KR20210107719A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020217022010A 2018-12-22 2019-12-20 자궁내막증과 연관된 미토콘드리아 dna 결실 Pending KR20210107719A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862784403P 2018-12-22 2018-12-22
US62/784,403 2018-12-22
US201962931173P 2019-11-05 2019-11-05
US62/931,173 2019-11-05
PCT/US2019/068098 WO2020132596A2 (en) 2018-12-22 2019-12-20 Mitochondrial dna deletions associated with endometriosis

Publications (1)

Publication Number Publication Date
KR20210107719A true KR20210107719A (ko) 2021-09-01

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KR1020217022010A Pending KR20210107719A (ko) 2018-12-22 2019-12-20 자궁내막증과 연관된 미토콘드리아 dna 결실

Country Status (9)

Country Link
US (1) US20220251655A1 (https=)
EP (1) EP3899050A2 (https=)
JP (2) JP7649745B2 (https=)
KR (1) KR20210107719A (https=)
CN (1) CN113227400A (https=)
AU (2) AU2019401465A1 (https=)
CA (1) CA3124497A1 (https=)
SG (1) SG11202106711YA (https=)
WO (1) WO2020132596A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112200270B (zh) * 2020-11-17 2022-12-20 金弗康生物科技(上海)股份有限公司 一种用于纠正高通量组学数据缺失的数据分区填充方法
GB202114374D0 (en) * 2021-10-07 2021-11-24 Univ Edinburgh Endometriosis biomarker
GB202204595D0 (en) * 2022-03-30 2022-05-11 Univ Newcastle Methods dor determining mitochondrial DNA damage
CN115404274A (zh) * 2022-11-01 2022-11-29 广东省生殖科学研究所(广东省生殖医院) 一种甲基化位点在子宫内膜异位症诊断和分型中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7871778B2 (en) * 2007-04-25 2011-01-18 The Regents Of The University Of California Methods of diagnosing endometriosis
CA2719718C (en) * 2008-03-28 2019-07-02 Mdna Life Sciences Inc. Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Also Published As

Publication number Publication date
CA3124497A1 (en) 2020-06-25
SG11202106711YA (en) 2021-07-29
AU2026202367A1 (en) 2026-04-16
WO2020132596A3 (en) 2020-07-23
AU2019401465A1 (en) 2021-07-22
JP2025087867A (ja) 2025-06-10
JP2022514924A (ja) 2022-02-16
EP3899050A2 (en) 2021-10-27
WO2020132596A2 (en) 2020-06-25
JP7649745B2 (ja) 2025-03-21
US20220251655A1 (en) 2022-08-11
CN113227400A (zh) 2021-08-06

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