KR20210097209A - 유방암 재발 예방용 백신 - Google Patents

유방암 재발 예방용 백신 Download PDF

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Publication number
KR20210097209A
KR20210097209A KR1020217023573A KR20217023573A KR20210097209A KR 20210097209 A KR20210097209 A KR 20210097209A KR 1020217023573 A KR1020217023573 A KR 1020217023573A KR 20217023573 A KR20217023573 A KR 20217023573A KR 20210097209 A KR20210097209 A KR 20210097209A
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KR
South Korea
Prior art keywords
patients
peptide
vaccine
composition
leu
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Abandoned
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KR1020217023573A
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English (en)
Korean (ko)
Inventor
조지 이. 피플스
포니아 사티발란
Original Assignee
더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드
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Application filed by 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 filed Critical 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드
Publication of KR20210097209A publication Critical patent/KR20210097209A/ko
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/38—Antigens from snakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
    • A61K40/4205—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/812—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/49—Breast

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020217023573A 2007-06-01 2008-04-11 유방암 재발 예방용 백신 Abandoned KR20210097209A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94152407P 2007-06-01 2007-06-01
US60/941,524 2007-06-01
KR1020207004398A KR102283639B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
PCT/US2008/060044 WO2008150577A1 (en) 2007-06-01 2008-04-11 Vaccine for the prevention of breast cancer relapse

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020207004398A Division KR102283639B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신

Publications (1)

Publication Number Publication Date
KR20210097209A true KR20210097209A (ko) 2021-08-06

Family

ID=40094045

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020217023573A Abandoned KR20210097209A (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020207004398A Expired - Fee Related KR102283639B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020097027587A Expired - Fee Related KR101572474B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020187014920A Expired - Fee Related KR102079921B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020157007937A Expired - Fee Related KR101863534B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020207004398A Expired - Fee Related KR102283639B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020097027587A Expired - Fee Related KR101572474B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020187014920A Expired - Fee Related KR102079921B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신
KR1020157007937A Expired - Fee Related KR101863534B1 (ko) 2007-06-01 2008-04-11 유방암 재발 예방용 백신

Country Status (16)

Country Link
US (6) US8222214B2 (enExample)
EP (2) EP2162149B1 (enExample)
JP (6) JP5635399B2 (enExample)
KR (5) KR20210097209A (enExample)
CN (2) CN105816867A (enExample)
AU (1) AU2008260399C1 (enExample)
CA (1) CA2687368C (enExample)
CY (1) CY1114912T1 (enExample)
DK (1) DK2162149T3 (enExample)
ES (1) ES2445399T3 (enExample)
HR (1) HRP20140102T1 (enExample)
MX (1) MX2009012858A (enExample)
PL (1) PL2162149T3 (enExample)
PT (1) PT2162149E (enExample)
SI (1) SI2162149T1 (enExample)
WO (1) WO2008150577A1 (enExample)

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US20160258951A1 (en) * 2013-10-28 2016-09-08 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods of monitoring immune responses
US10434152B2 (en) * 2014-02-20 2019-10-08 Wayne State University HER2 antigenic polypeptide compositions, and methods for their use in treatment and prevention of carcinomas
BR112018015480A2 (pt) 2016-01-29 2019-05-21 Sorrento Therapeutics, Inc. proteínas de ligação ao antígeno que se ligam a pd-l1
EP3463438B1 (en) * 2016-05-31 2022-04-06 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Vaccine therapy for treatment of endometrial and ovarian cancer
EP3866853A4 (en) * 2018-10-21 2022-08-03 SLSG Limited LLC MULTI-IMMUNOTHERAPY FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER
CN117280219A (zh) 2021-05-04 2023-12-22 阿斯顿科学公司 Her2疫苗组合物
KR20230017640A (ko) 2021-07-28 2023-02-06 주식회사 애스톤사이언스 Her2 백신 조성물

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Also Published As

Publication number Publication date
EP2722336A1 (en) 2014-04-23
JP2018199691A (ja) 2018-12-20
CN101678093A (zh) 2010-03-24
KR20200019776A (ko) 2020-02-24
KR102283639B1 (ko) 2021-08-02
EP2162149A4 (en) 2012-07-25
CN105816867A (zh) 2016-08-03
JP2022095926A (ja) 2022-06-28
ES2445399T3 (es) 2014-03-03
US20150182609A1 (en) 2015-07-02
SI2162149T1 (sl) 2014-04-30
DK2162149T3 (da) 2014-02-10
KR20180061412A (ko) 2018-06-07
EP2162149A1 (en) 2010-03-17
US20130189290A1 (en) 2013-07-25
JP7072467B2 (ja) 2022-05-20
US20190060429A1 (en) 2019-02-28
WO2008150577A1 (en) 2008-12-11
JP6097724B2 (ja) 2017-03-15
JP2017071607A (ja) 2017-04-13
MX2009012858A (es) 2010-02-03
JP2014237653A (ja) 2014-12-18
JP2010529026A (ja) 2010-08-26
JP5635399B2 (ja) 2014-12-03
KR102079921B1 (ko) 2020-02-21
US8222214B2 (en) 2012-07-17
EP2162149B1 (en) 2013-11-06
AU2008260399C1 (en) 2014-07-17
US20100209443A1 (en) 2010-08-19
US20220347281A1 (en) 2022-11-03
CA2687368A1 (en) 2008-12-11
KR20150106870A (ko) 2015-09-22
CY1114912T1 (el) 2017-01-25
CA2687368C (en) 2018-10-30
AU2008260399B2 (en) 2014-01-16
HRP20140102T1 (hr) 2014-03-28
US20220241389A1 (en) 2022-08-04
JP2021001218A (ja) 2021-01-07
KR101863534B1 (ko) 2018-06-04
PT2162149E (pt) 2014-02-12
KR20100027187A (ko) 2010-03-10
US8796220B2 (en) 2014-08-05
PL2162149T3 (pl) 2014-04-30
US10842856B2 (en) 2020-11-24
KR101572474B1 (ko) 2015-11-30
US9370560B2 (en) 2016-06-21
AU2008260399A8 (en) 2010-01-07
AU2008260399A1 (en) 2008-12-11

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