KR20200079493A - 중합체 미립자-금속 나노입자 복합체의 미세유체 보조식 제작 - Google Patents

중합체 미립자-금속 나노입자 복합체의 미세유체 보조식 제작 Download PDF

Info

Publication number
KR20200079493A
KR20200079493A KR1020207011951A KR20207011951A KR20200079493A KR 20200079493 A KR20200079493 A KR 20200079493A KR 1020207011951 A KR1020207011951 A KR 1020207011951A KR 20207011951 A KR20207011951 A KR 20207011951A KR 20200079493 A KR20200079493 A KR 20200079493A
Authority
KR
South Korea
Prior art keywords
metal
complex
polymer
precursor
nanoparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020207011951A
Other languages
English (en)
Korean (ko)
Inventor
리디자 말릭
쉬에펑 장
케이스 모턴
테오도르 베레스
Original Assignee
내션얼 리서치 카운슬 오브 캐나다
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 내션얼 리서치 카운슬 오브 캐나다 filed Critical 내션얼 리서치 카운슬 오브 캐나다
Publication of KR20200079493A publication Critical patent/KR20200079493A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/01Processes of polymerisation characterised by special features of the polymerisation apparatus used
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F292/00Macromolecular compounds obtained by polymerising monomers on to inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5115Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/44Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/46Polymerisation initiated by wave energy or particle radiation
    • C08F2/48Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/1006Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/1006Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/103Esters of polyhydric alcohols or polyhydric phenols of trialcohols, e.g. trimethylolpropane tri(meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00Use of inorganic substances as compounding ingredients
    • C08K3/02Elements
    • C08K3/08Metals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/05Alcohols; Metal alcoholates
    • C08K5/053Polyhydroxylic alcohols
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/10Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to inorganic materials
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N21/658Raman scattering enhancement Raman, e.g. surface plasmons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00Manufacture or treatment of nanostructures
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00Use of inorganic substances as compounding ingredients
    • C08K3/02Elements
    • C08K3/08Metals
    • C08K2003/0831Gold
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00Specific properties of additives
    • C08K2201/011Nanostructured additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Medicinal Preparation (AREA)
  • Polymerisation Methods In General (AREA)
KR1020207011951A 2017-09-26 2018-09-25 중합체 미립자-금속 나노입자 복합체의 미세유체 보조식 제작 Ceased KR20200079493A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762563206P 2017-09-26 2017-09-26
US62/563,206 2017-09-26
PCT/CA2018/051202 WO2019060989A1 (en) 2017-09-26 2018-09-25 MICROFLUIDICALLY ASSISTED MANUFACTURE OF METAL POLYMER-NANOPARTICLE MICROPARTICLE COMPOSITES

Publications (1)

Publication Number Publication Date
KR20200079493A true KR20200079493A (ko) 2020-07-03

Family

ID=65900385

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207011951A Ceased KR20200079493A (ko) 2017-09-26 2018-09-25 중합체 미립자-금속 나노입자 복합체의 미세유체 보조식 제작

Country Status (7)

Country Link
US (1) US11753485B2 (https=)
EP (1) EP3688093A4 (https=)
JP (1) JP7341990B2 (https=)
KR (1) KR20200079493A (https=)
AU (1) AU2018340884A1 (https=)
CA (1) CA3076935A1 (https=)
WO (1) WO2019060989A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018340885A1 (en) * 2017-09-26 2020-05-07 National Research Council Of Canada Polymer film-metal composites
US12005448B2 (en) 2018-08-17 2024-06-11 The Regents Of The University Of California Systems and methods of using anisotropic nanostructures in microfluidic devices for binding and optional release of molecules and cells
CN111045295B (zh) * 2019-12-25 2023-10-31 杭州光粒科技有限公司 金属纳米颗粒掺杂的光致聚合物组合物以及光栅
JP2023548869A (ja) 2020-11-16 2023-11-21 イルミナ ケンブリッジ リミテッド 官能化プラズモンナノ構造
US20230058578A1 (en) * 2021-08-17 2023-02-23 GE Precision Healthcare LLC High-aspect ratio metallized structures
US12521917B2 (en) * 2021-08-17 2026-01-13 Honeywell Federal Manufacturing & Technologies, Llc Polymerizing grafted nanoparticles using flow chemistry

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2517204A1 (en) * 2003-03-13 2004-09-23 Eugenia Kumacheva Method of producing hybrid polymer-inorganic materials
JP2007089446A (ja) 2005-09-28 2007-04-12 Ebara Corp センス鎖とアンチセンス鎖を含むpcr増幅産物からいずれか一方の一本鎖核酸を単離する方法
JP2013509585A (ja) 2009-10-30 2013-03-14 メドテック ディテクト、エル・エル・シー インプリントポリマー及びフォトクロミックスイッチ分子を用いて分析物を比色検出するための組成物、装置及び方法
JP6164845B2 (ja) 2009-11-27 2017-07-19 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se セキュリティ要素及びホログラムのための被覆組成物
US20110183140A1 (en) 2010-01-22 2011-07-28 University Of Maryland, College Park Method for Polymer Coating and Functionalization of Metal Nanorods
JP5697964B2 (ja) * 2010-12-17 2015-04-08 丸善石油化学株式会社 光硬化性組成物並びにこれを用いた金属ナノ粒子分散膜及び導電性薄膜の製造方法
DE102012201475B4 (de) 2012-02-01 2014-12-18 Gna Biosolutions Gmbh Verfahren zum Vervielfältigen von Nukleinsäuren
JP5668001B2 (ja) 2012-03-05 2015-02-12 丸善製薬株式会社 皮膚化粧料及び頭髪化粧料
WO2016046847A1 (en) 2014-09-23 2016-03-31 Council Of Scientific & Industrial Research Metal embedded hydrophilic polymer for drug delivery applications
EP3073321A1 (en) 2015-03-26 2016-09-28 Centre National de la Recherche Scientifique (C.N.R.S.) Metal-polymer composite material

Also Published As

Publication number Publication date
EP3688093A1 (en) 2020-08-05
WO2019060989A1 (en) 2019-04-04
JP2020535278A (ja) 2020-12-03
EP3688093A4 (en) 2021-05-26
US11753485B2 (en) 2023-09-12
US20200223948A1 (en) 2020-07-16
AU2018340884A1 (en) 2020-05-07
JP7341990B2 (ja) 2023-09-11
CA3076935A1 (en) 2019-04-04

Similar Documents

Publication Publication Date Title
US11753485B2 (en) Microfluidic assisted fabrication of polymer microparticle-metal nanoparticle composites
US12331287B1 (en) Assays and other reactions involving droplets
Zhao et al. Microfluidic synthesis of barcode particles for multiplex assays
Hao et al. Microfluidic synthesis of functional inorganic micro-/nanoparticles and applications in biomedical engineering
Luo et al. Microfluidic devices in fabricating nano or micromaterials for biomedical applications
Erdem et al. In situ synthesis and dynamic simulation of molecularly imprinted polymeric nanoparticles on a micro-reactor system
Wang et al. Self-assembly of colloids based on microfluidics
Lim et al. Gold nanospheres assembled on hydrogel colloids display a wide range of thermoreversible changes in optical bandwidth for various plasmonic-based color switches
Sun et al. Microfluidic fabrication of multifunctional particles and their analytical applications
Brown et al. Polymersome production on a microfluidic platform using pH sensitive block copolymers
Mahhengam et al. Applications of microfluidic devices in the diagnosis and treatment of cancer: A review study
Hu et al. Preparation of biofunctionalized quantum dots using microfluidic chips for bioimaging
Qiao et al. Preparation of polymer@ AuNPs with droplets approach for sensing serum copper ions
Generalova et al. Submicron polymer particles containing fluorescent semiconductor nanocrystals CdSe/ZnS for bioassays
Kwon et al. Aggregation-Driven Controllable Plasmonic Transition of Silica-Coated Gold Nanoparticles with Temperature-Dependent Polymer–Nanoparticle Interactions for Potential Applications in Optoelectronic Devices
Han et al. Microfluidic synthesis of functional nanoparticles
Wu et al. Multicompartmental hydrogel microspheres as a tool for multicomponent analysis
Peng et al. A droplet-based microfluidics route to temperature-responsive colloidal molecules
Suh et al. Using stop-flow lithography to produce opaque microparticles: Synthesis and modeling
CN106770135A (zh) 金属增强荧光信号的编码微球及其制备方法和应用
Lee et al. High throughput synthesis of uniform biocompatible polymer beads with high quantum dot loading using microfluidic jet-mode breakup
Mazetyte-Stasinskiene et al. Four-level structural hierarchy: microfluidically supported synthesis of polymer particle architectures incorporating fluorescence-labeled components and metal nanoparticles
Li et al. Microfluidically assisted construction of hierarchical multicomponent microparticles for short intermediate diffusion paths in heterogeneous catalysis
Pittermannova et al. Functionalized hydrogel microparticles prepared by microfluidics and their interaction with tumour marker carbonic anhydrase IX
Wang et al. Organoclay‐assisted interfacial polymerization for microfluidic production of monodisperse PEG‐microdroplets and in situ encapsulation of E. coli

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20200424

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210914

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230725

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20240201

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230725

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I