KR20200067145A - Axl-특이적 항체 및 그의 용도 - Google Patents

Axl-특이적 항체 및 그의 용도 Download PDF

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KR20200067145A
KR20200067145A KR1020207010151A KR20207010151A KR20200067145A KR 20200067145 A KR20200067145 A KR 20200067145A KR 1020207010151 A KR1020207010151 A KR 1020207010151A KR 20207010151 A KR20207010151 A KR 20207010151A KR 20200067145 A KR20200067145 A KR 20200067145A
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ser
seq
thr
antibody
gly
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케빈 헨리
마리아 루즈 자라밀로
콜린 로저 메켄지
안 마르실
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내셔날 리서치 카운실 오브 캐나다
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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KR1020207010151A 2017-09-13 2018-09-10 Axl-특이적 항체 및 그의 용도 Ceased KR20200067145A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762557870P 2017-09-13 2017-09-13
US62/557,870 2017-09-13
PCT/CA2018/051108 WO2019051586A1 (en) 2017-09-13 2018-09-10 AXL SPECIFIC ANTIBODIES AND USES THEREOF

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KR20200067145A true KR20200067145A (ko) 2020-06-11

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US (2) US11739154B2 (https=)
EP (1) EP3681912A4 (https=)
JP (1) JP7366886B2 (https=)
KR (1) KR20200067145A (https=)
CN (1) CN111263770A (https=)
AU (1) AU2018333290A1 (https=)
BR (1) BR112020005011A2 (https=)
CA (1) CA3075531A1 (https=)
IL (1) IL273157A (https=)
RU (1) RU2020113027A (https=)
SG (1) SG11202002331QA (https=)
WO (1) WO2019051586A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110268108B (zh) 2016-12-12 2022-09-06 埃克切拉生物科学公司 用于使用微毛细管阵列进行筛选的方法和系统
EP3562796B1 (en) 2016-12-30 2023-04-19 Xcella Biosciences, Inc. Multi-stage sample recovery system
ES3039910T3 (en) 2018-12-06 2025-10-27 Xcella Biosciences Inc Lateral loading of microcapillary arrays
CN113045664B (zh) * 2019-11-28 2023-05-12 尚健单抗（北京）生物技术有限公司 一种分离的结合抗原axl的蛋白及其用途
WO2021154156A1 (en) * 2020-01-31 2021-08-05 Agency For Science, Technology And Research Anti-axl antibody and uses thereof
WO2021253335A1 (zh) * 2020-06-18 2021-12-23 深圳迈瑞生物医疗电子股份有限公司 抗可溶性cd14亚型抗体、试剂盒及其应用
MX2023005571A (es) * 2020-11-12 2023-07-31 Bioatla Inc Metodos de tratamiento de canceres que expresan axl con anticuerpos anti-axl, fragmentos de anticuerpos y sus inmunoconjugados.
CN115125272B (zh) * 2021-03-29 2024-04-19 复旦大学 一种car-t治疗载体及其构建方法和应用
JP2024523436A (ja) * 2021-06-16 2024-06-28 上海▲シン▼湾生物科技有限公司 Ａｘｌタンパク質を標的とする抗体及びその抗原結合断片、その調製方法と使用
EP4724501A1 (en) * 2023-06-06 2026-04-15 Joint Stock Company "Biocad" Monoclonal antibody or antigen-binding fragment thereof that specifically binds to axl, and use thereof
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