KR20200003821A - 상피 장벽 기능 장애 치료용 단백질 - Google Patents

상피 장벽 기능 장애 치료용 단백질 Download PDF

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Publication number
KR20200003821A
KR20200003821A KR1020197032830A KR20197032830A KR20200003821A KR 20200003821 A KR20200003821 A KR 20200003821A KR 1020197032830 A KR1020197032830 A KR 1020197032830A KR 20197032830 A KR20197032830 A KR 20197032830A KR 20200003821 A KR20200003821 A KR 20200003821A
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KR
South Korea
Prior art keywords
seq
amino acid
acid sequence
protein
therapeutic protein
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Ceased
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KR1020197032830A
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English (en)
Korean (ko)
Inventor
앤드류 원희 한
앤드류 윗먼 굿이어
타룬미트 구즈랄
토드 자캐리 데산티스
카림 다바흐
토시히코 타케우치
예 진
미치 이주미 윌콕슨
스테파니 바나스
Original Assignee
세컨드 게놈, 아이엔씨.
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Application filed by 세컨드 게놈, 아이엔씨. filed Critical 세컨드 게놈, 아이엔씨.
Priority to KR1020237032575A priority Critical patent/KR102903277B1/ko
Publication of KR20200003821A publication Critical patent/KR20200003821A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2/00Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
KR1020197032830A 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질 Ceased KR20200003821A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237032575A KR102903277B1 (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762482963P 2017-04-07 2017-04-07
US62/482,963 2017-04-07
US201762607706P 2017-12-19 2017-12-19
US62/607,706 2017-12-19
US201762611334P 2017-12-28 2017-12-28
US62/611,334 2017-12-28
PCT/US2018/026447 WO2018187682A1 (en) 2017-04-07 2018-04-06 Proteins for the treatment of epithelial barrier function disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237032575A Division KR102903277B1 (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Publications (1)

Publication Number Publication Date
KR20200003821A true KR20200003821A (ko) 2020-01-10

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197032830A Ceased KR20200003821A (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질
KR1020237032575A Active KR102903277B1 (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Family Applications After (1)

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KR1020237032575A Active KR102903277B1 (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Country Status (12)

Country Link
US (3) US10251933B2 (https=)
EP (1) EP3606542A4 (https=)
JP (2) JP7789303B2 (https=)
KR (2) KR20200003821A (https=)
CN (1) CN110769844B (https=)
AU (2) AU2018248324B2 (https=)
CA (1) CA3059354A1 (https=)
IL (1) IL269853A (https=)
MX (2) MX393998B (https=)
SG (1) SG11201909334TA (https=)
TW (1) TWI797116B (https=)
WO (1) WO2018187682A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10251933B2 (en) * 2017-04-07 2019-04-09 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
EP3773644A4 (en) * 2018-04-06 2021-06-02 Second Genome, Inc. PROTEINS FOR TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
CN113347983A (zh) * 2018-10-09 2021-09-03 第二基因组股份有限公司 用于递送有效治疗上皮屏障功能障碍的蛋白质的乳酸乳球菌表达系统
US20210079086A1 (en) * 2019-08-21 2021-03-18 Astrazeneca Collaboration Ventures, Llc Use of Brazikumab to Treat Crohn's Disease
US11666629B2 (en) * 2020-01-10 2023-06-06 National Taipei University Of Technology Peptide interacting with toll-like receptor 2 and the composition comprising the same
CN113773364B (zh) * 2021-08-25 2023-04-28 无锡市儿童医院 小分子肽及其制备方法和应用
CN120882418A (zh) * 2022-11-04 2025-10-31 MiNK治疗公司 B细胞成熟抗原(bcma)嵌合抗原受体不变自然杀伤t细胞及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5571702A (en) 1991-03-29 1996-11-05 Genentech, Inc. Amplification method for detection of human PF4A receptors
AR053579A1 (es) * 2005-04-15 2007-05-09 Genentech Inc Tratamiento de la enfermedad inflamatoria intestinal (eii)
DK3061766T3 (da) * 2009-04-28 2020-03-16 Univ Vanderbilt Sammensætninger og fremgangsmåder til behandlingen af sygdomme der involverer epitelcelleapoptose
GB201117313D0 (en) * 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
JP2014093482A (ja) 2012-11-06 2014-05-19 Toshiba Corp 固体撮像装置の製造方法および固体撮像装置
GB201306536D0 (en) * 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2015014973A2 (en) * 2013-07-31 2015-02-05 Institut National De La Recherche Agronomique Use of specific glycoside phosphorylases for the implementation of phosphorolysis or reverse phosphorolysis reactions
WO2016203221A1 (en) * 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
US10251933B2 (en) 2017-04-07 2019-04-09 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) * 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11174293B2 (en) 2017-06-02 2021-11-16 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders

Also Published As

Publication number Publication date
KR102903277B1 (ko) 2025-12-23
US20240066095A1 (en) 2024-02-29
US20180289770A1 (en) 2018-10-11
MX393998B (es) 2025-03-24
US20200148728A1 (en) 2020-05-14
AU2023202844A1 (en) 2023-07-06
CN110769844B (zh) 2025-01-21
US11207376B2 (en) 2021-12-28
CA3059354A1 (en) 2018-10-11
TW201841649A (zh) 2018-12-01
KR20230144097A (ko) 2023-10-13
EP3606542A1 (en) 2020-02-12
MX2019012051A (es) 2020-02-12
TWI797116B (zh) 2023-04-01
JP7789303B2 (ja) 2025-12-22
IL269853A (en) 2019-11-28
US10251933B2 (en) 2019-04-09
JP2020516615A (ja) 2020-06-11
JP2024037834A (ja) 2024-03-19
AU2018248324A1 (en) 2019-10-31
WO2018187682A1 (en) 2018-10-11
AU2018248324B2 (en) 2023-02-09
CN110769844A (zh) 2020-02-07
SG11201909334TA (en) 2019-11-28
MX2022008842A (es) 2022-08-02
EP3606542A4 (en) 2021-01-20

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