KR20190109231A - An plasma treatment apparatus for treatmenting cervical cancer - Google Patents

Abstract

The present invention relates to a plasma treatment device for cervical cancer treatment, comprising: a probe-type device housing which can be inserted into a vaginal canal in order to treat a cervix; a plasma generating portion for generating plasma energy to the front end of the device housing; and a plasma guide portion installed on the front end portion of the device housing to guide plasma generated by the plasma generating portion such that the same is focused toward the cervix.

Description

Plasma treatment device for cervical cancer healing {AN PLASMA TREATMENT APPARATUS FOR TREATMENTING CERVICAL CANCER}

The present invention relates to a plasma treatment apparatus for cervical cancer treatment, and more particularly, to a plasma treatment apparatus for treating cervical cancer precancerous lesions using plasma.

Cervical cancer is the fourth most common female cancer in the world. More than half a million cancers were diagnosed worldwide in 2012, of which approximately 50% of patients died from the disease.

In the United States, about 13,000 invasive cervical cancers and about 4,100 cancer-related deaths occur each year.

Since cervical cancer undergoes a stage of precancerous lesions longer than other cancers, it is a disease that can be cured only by early detection, and it is possible to discriminate abnormalities through simpler tests than diagnostic tests of stomach, lung, colon and thyroid cancer Given the fact, early detection and active treatment of cervical precancerous lesions is important.

In Korea, while cervical cancer continues to decrease, the number of inventors of cervical precancerous lesions is generally increasing, and the frequency of medical use is rapidly increasing.

Currently, there are no drugs for treating cervical precancerous lesions, the only treatment is surgical resection, and surgical resection methods include loop electrosurgical excision procedure (LEEP), cervical coniztion, Laser excision and hysterectomy.

By the way, such surgical therapy causes a social problem of premature birth, miscarriage, infertility and reduced fertility rate, and there is a problem that there is a risk of relapse in incomplete surgery. In addition, although the probability is not high, there is a risk of premature birth, cerebral palsy, retinal disorder, and low prematurity.

As such, cervical precancerous lesions can cause a sudden increase in incidence in younger ages and severe pregnancy-related complications of conventional resections.

On the other hand, in recent years, among the methods for the treatment of cancer cells, various treatment methods in addition to the surgical treatment method has been actively researched and developed, among which the development of a plasma treatment device that can kill cancer cells without causing pain is actively made have.

Atmospheric pressure plasma is an ionized or electrically neutral neutral gas containing an active ingredient gas containing electrons and ions, free radicals, reactive molecules, ultraviolet and visible photons, and a thermal or non-thermal plasma. Can be classified as).

In particular, non-thermal atmospheric pressure plasmas are emerging as new tools in biomedical and pharmaceutical applications because they can interact with targeted biomaterials without causing thermal damage to surrounding tissues. However, as shown in Korean Patent Nos. 10-1592081 and 10-1248668, there is no published technique for killing cervical cancer cells using low temperature atmospheric pressure or atmospheric pressure plasma, and cervical cancer cells using low temperature atmospheric plasma. There is no public technology, and there is an urgent need for technological development.

Republic of Korea Patent No. 10-1592081 Republic of Korea Patent No. 10-1248668

The present invention has been made to solve the above problems, an object of the present invention is to provide a plasma treatment device for cervical cancer that can heal precancerous lesions of cervical cancer using a cold atmospheric plasma.

Plasma treatment device for cervical cancer treatment of the present invention for achieving the above object, and a probe-type device housing that can enter the planar neck to heal the cervix; A plasma generator for generating plasma energy at a tip of the device housing; And a plasma guide part installed at the distal end of the device housing to guide the plasma generated by the plasma generating part to be concentrated on the cervix side.

As a result, cervical cancer cells can be killed and healed using plasma energy.

Here, the plasma guide portion preferably includes an outer diameter guide member extending and extending from the edge of the tip of the device housing to surround and support the uterine outer diameter tube.

In addition, the outer diameter pipe guide member, the coupling portion coupled to the front end of the device housing; And expansion ribs formed so as to extend from the coupling portion to surround the uterine outer tube.

As a result, the plasma energy is guided to the uterine outer tube to increase the cancer cell healing effect of the uterine tube.

In addition, the plasma guide unit may include an outer tube guide member extending to gradually narrow from the edge of the front end of the device housing to guide the plasma energy to the uterine inner tube.

As a result, plasma energy can be concentrated in the uterine endoscope to effectively cure cancer cells in the uterine endoscope.

In addition, the plasma generation unit may include a low temperature atmospheric dielectric barrier (DBD) surface discharge plasma.

In addition, a plasma treatment apparatus for cervical cancer treatment according to another aspect of the present invention for achieving the above object, a probe-type device housing that can be entered into the planar to cure cervical cancer; A first plasma generating module installed in the device housing to generate plasma for healing the uterine outer tube; And a second plasma generating module installed in the device housing and generating a plasma for treating the cervical endoscope.

As a result, different types of plasma energy may be concentrated into the uterine outer tube and the uterine inner tube, thereby effectively treating cervical cancer cells.

Here, the second plasma generating module is preferably arranged to generate plasma energy to the central portion of the plasma generating surface generated by the first plasma generating module.

As a result, the cancer cells of the endometrial canal may be concentrated using plasma energy generated by the second plasma generating module.

The first plasma generating module may include a low temperature atmospheric dielectric barrier (DBD) surface discharge plasma.

The second plasma generating module may include a low temperature atmospheric plasma jet capable of intensively generating plasma at a central portion of the tip of the device housing.

As a result, a relatively large area of the endometrial canal is healed by using a cold atmospheric surface discharge plasma, and a relatively narrow area of the endometrial can be intensively treated by using a cold atmospheric plasma jet.

In addition, the first and second plasma generating module preferably comprises a low-temperature atmospheric pressure surface discharge plasma and a low-temperature atmospheric pressure plasma jet, respectively.

As a result, it is possible to treat each of the uterine outer tube and the endometrial tube using a cold atmospheric plasma.

The apparatus may further include a plasma guide unit installed in the device housing to guide plasma energy generated by the first and second plasma generating modules to be concentrated on the cervix.

The plasma guide unit may include an outer diameter guide member which extends from the edge of the front end of the device housing to guide the surface discharge plasma energy generated by the first plasma generator to the ectopic landscape.

The plasma guide unit may further include an inner diameter guide member connected to a central portion of the front end of the device housing to guide the plasma energy generated by the second plasma generating module to be concentrated in the uterine cervix.

In addition, the inner diameter guide member may be formed so as to protrude in the form of a nozzle from the center of the front end of the device housing is inserted into the intrauterine landscape to transmit plasma energy.

As a result, the low-temperature atmospheric pressure dielectric barrier surface discharge plasma energy is concentrated in the uterine outer tube, and the low-temperature atmospheric pressure plasma jet is guided in the uterine inner tube, thereby improving the healing effect.

In addition, the outer diameter pipe guide member, the coupling portion coupled to the front end of the device housing; And expansion ribs formed so as to extend from the coupling portion to surround the uterine outer tube.

The apparatus may further include an internal structure installed inside the device housing to isolate the first and second plasma generating modules.

Thus, the first and second plasma generating modules driven independently of each other can be installed in one device housing.

The internal structure may include a quartz tube or an insulator tube, and a gas supply path may be formed between the quartz tube or insulator tube and the device housing to supply a gas to the plasma generator of the first plasma generation module.

In addition, it is preferable to further include a camera module installed on the front end of the device housing to photograph the site to heal.

As a result, when the device is drawn into the human body for the treatment of the cervix, the device may be cured by positioning the device at the correct position through an image of the internal state of the human body.

In addition, it is preferable to further include a suction unit for gas recovery provided in the apparatus housing to recover the gas supplied to the plasma generating unit used for the plasma generation.

As a result, the gas used to generate the plasma can be recovered and prevented from remaining in the human body or released into the atmosphere.

Plasma treatment device for cervical cancer treatment of the present invention can effectively treat cervical cancer by using plasma energy.

In particular, by providing a guide portion for concentrating the generated plasma to the site of healing, cancer cells of the area for healing can be effectively cured.

In addition, the uterine outer tube can treat a large area using a large-area surface discharge plasma generator, and the uterine inner tube can provide a complex treatment device for intensive treatment using a plasma jet. There is an advantage that the inner diameter can heal at the same time using a single treatment device.

In addition, by providing the external tube guide member and the internal tube guide member in one treatment device, plasma energy can be concentrated on the uterine outer tube and the uterine inner tube, thereby improving the healing effect.

In addition, both the uterine outer tube and the uterine inner tube can be provided with a treatment device that can be intensively treated using a plasma jet.

In addition, by further comprising a camera module that can photograph the position to heal and the healing process, it is possible to accurately find and heal the treatment position, to confirm the healing process and to data.

In addition, by providing a gas suction unit, it is possible to recover the gas used in the treatment to prevent the gas remaining in the human body, and to prevent it from being released into the atmosphere.

1 is a schematic diagram showing a plasma treatment apparatus for cervical cancer treatment according to a first embodiment of the present invention.
2 and 3 are schematic views for explaining and extracting the plasma generating unit shown in FIG.
4 is a view for explaining a state of healing the uterine outer tube using the plasma treatment apparatus shown in FIG.
FIG. 5 is a view illustrating a state in which a camera module and a gas suction unit are added in the state of FIG. 1.
Figure 6 is a schematic diagram showing a plasma treatment apparatus for cervical cancer treatment according to a second embodiment of the present invention.
7 is a view for explaining the process of healing the endometrial canal using the plasma treatment apparatus shown in FIG.
FIG. 8 is a view illustrating a state in which a camera module and a gas suction unit are added in the state of FIG. 6.
9 is a schematic diagram showing a plasma treatment apparatus for cervical cancer treatment according to a third embodiment of the present invention.
10 is a schematic diagram showing a plasma treatment apparatus for cervical cancer treatment according to a fourth embodiment of the present invention.
FIG. 11 is a view illustrating a state in which a camera module and a gas suction unit are added in the state of FIG. 9.
12 is a schematic diagram illustrating a process of healing the cervix using the plasma treatment apparatus for cervical cancer healing shown in FIG. 10.
FIG. 13 is a schematic diagram illustrating a process of healing an external cervix and an internal cervix using a plasma treatment apparatus for cervical cancer treatment shown in FIG. 12.
14 is a schematic view showing a plasma treatment apparatus for cervical cancer treatment according to a fifth embodiment of the present invention.
FIG. 15 is a schematic right side view of the plasma treatment apparatus shown in FIG. 14.
FIG. 16 is a view illustrating a state in which a camera module and a gas suction unit are added in the state of FIG. 15.

Hereinafter, with reference to the accompanying drawings will be described in detail the plasma treatment device for cervical cancer treatment according to a preferred embodiment of the present invention.

1 to 4, the plasma treatment apparatus 100 for treating cervical cancer according to the first embodiment of the present invention may generate plasma energy to the device housing 110 and the tip of the device housing 110. The plasma generating unit 120, and the plasma guide unit 130 for guiding the generated plasma energy to the cervix side to be treated.

The device housing 110 is formed of an insulating material and has a tubular shape having a predetermined length. Preferably, the device housing 110 has a sufficient length to enter the vagina of the uterus for the purpose of treating the cervix, and preferably has a circular tubular structure.

A gas supply path 111 may be formed in the device housing 110 to supply gas to the plasma generator 120 installed at the tip of the device housing 110. The gas supply path 111 may be formed between the device housing 110 and the internal structure 113 installed inside the device housing 110. The internal structure 113 may be formed of an insulating material, and may include, for example, a quartz tube or a ceramic tube.

For example, the plasma generator 120 may have a structure of a so-called low temperature atmospheric pressure dielectric barrier surface discharge plasma generation method. That is, as shown in FIGS. 1, 2, and 3, the plasma generating unit 120 is installed at the front end of the device housing 110, and has a first electrode installed on the glass or dielectric substrate 121. 123 and a dielectric layer 127 provided on the substrate 121 to insulate the second electrode 125 and the first and second electrodes 123 and 125. A gas supply passage h may be minutely formed in the glass substrate 121 and the dielectric layer 127 to supply gas out of the dielectric layer 127. The first and second electrodes 123 and 125 formed on the substrate 121 may be stacked and formed by a semiconductor manufacturing process such as photolithography, screen printing, or ceramic electrode formation, and may be formed in various patterns. For example, the first electrode 123 and the second electrode 125 may be formed in a surface discharge electrode structure pattern of the plasma TV. Of course, the gas supply passage (gas hole) formed in the substrate 121 and the dielectric layer 127 may be formed through a general micromechanical process or a semiconductor manufacturing process. The dielectric layer 127 is formed to cover the first and second electrodes 123 and 125, and is formed to have a predetermined thickness so as to electrically cut off the outside and discharge the plasma effectively.

In addition, the secondary electron generation layer 128 and the hydration prevention layer 129 may be sequentially stacked on the outer side of the dielectric 127 to be further formed. The secondary electron generation layer 128 and the anti-hydration layer 129 may be formed by a semiconductor manufacturing process, such as the dielectric layer 127 and the electrodes 123 and 125. The secondary electron generation layer 128 may play a role of regenerating more charges from the generated plasma. The secondary electron generation layer 128 may be selectively applied, and in some cases, one anti-hydration layer 129 may be used. The film can also be laminated. The plasma generating unit 120 having the above configuration can be formed in a surface discharge structure with a desired large area without being restricted by the area, and electrode formation is performed by semiconductor manufacturing technology (photolithography technology, or lift-off or screen printing, etc.). Since it is possible to manufacture a fine electrode structure, it is possible to generate a high density plasma even at low power.

The plasma generator 120 having the above configuration is formed in the gas supply path 111 and the dielectric layer 127 while applying an alternating voltage to the first and second electrodes 123 and 125 with different polarities or the same polarity. When gas is supplied through the gas supply passage (gas hole) h, plasma is generated in a space outside the dielectric layer 127 surrounding the first and second electrodes 123 and 125 (see FIG. 3). In particular, when a voltage having the same polarity is applied to the first and second electrodes 123 and 125, the plasma is generated only when the object is located within a proper distance in the space outside the dielectric layer 127 (see FIG. 3).

Here, it is preferable that the interval between the first and second electrodes 123 and 125 is approximately 100 to 400 μm, the discharge voltage is set to 1 kV or less, and the discharge current is set to have a characteristic of 10 mA or less.

In addition, the above-described plasma generating unit 120 is just an example, and it is obvious that a known surface discharge type DBD plasma method capable of various configurations may be applied.

As shown in FIG. 4, the plasma guide unit 130 guides the plasma energy generated by the plasma generation unit 120 toward the uterine outer tube (extocervix) 10, which is a target human body. One example of the plasma guide unit 130 includes an outer tube guide member 131 for guiding the generated plasma connected to the distal end of the device housing 110 to the uterine cervix 10 of the cervix.

The outer diameter tube guide member 131 is a coupling portion 131a coupled to the front end of the device housing 110, and the expansion rib is formed to extend in all directions in the coupling portion 131a to surround the outer diameter tube of the cervix 131b is provided. The coupling part 131a has a cylindrical structure and may be coupled to an outer edge of the front end of the device housing 110. The expansion rib 131b is integrally formed with the coupling portion 131a and gradually extends in diameter from the coupling portion 131a. The expansion rib 131b having the above configuration is wrapped around the uterine outer tube 10 so that the plasma energy generated in the plasma generator 120 can be effectively guided to the uterine outer tube 10. Therefore, cancer cells of the uterine outer tube 10 can be effectively killed and healed.

In addition, as shown in FIG. 5, the cervical cancer treatment plasma treatment apparatus 100 according to the first embodiment of the present invention may further include a camera module 140 and a gas suction unit 150.

The camera module 140 may be installed at the tip of the device housing 110 or at the tip of the plasma generator 120. The image photographed by the camera module 140 is transmitted and displayed by a wired or wireless method to a separate image display device. Therefore, when the device housing 110 is drawn into the human body to heal, it enters while photographing the state of the human body, and accurately finds a position to heal to locate the tip of the device housing 110, and photographs the healing process. Data can be converted into medical data. At this time, the camera module 140 includes lighting, so that the inside of the human body can be taken while illuminating the light so as to easily check from the outside. The camera module 140 may be installed at the front end of the device housing 110 or may be installed at the guide unit 130. Of course, preferably, as shown in Figure 5, the camera module 140 is preferably installed in the center of the front end of the plasma generating unit 120. In this way, the position of the camera module 140 may be selectively designated and installed.

The gas recovery unit 150 is supplied to the plasma generation unit 120 to recover the gas used to generate the plasma. The gas recovery unit 150 is connected to the gas recovery nozzle 151 protruding toward the front end of the device housing 110 and the gas recovery nozzle 151 to the rear end of the device housing 110 to the external gas recovery device (not shown) And a gas recovery path 153 for connecting to H). The gas recovery nozzle 151 may be installed to protrude from the guide unit 130 or to protrude outward from the plasma generating unit 120 to recover a gas that may be introduced into the human body.

6 and 7, the plasma treatment apparatus 100 ′ according to the second embodiment of the present invention has plasma energy as an endocervical cannal 20 as the plasma guide unit 130 ′. It is characterized by having an inner diameter guide member 133 having a structure capable of guiding to be concentrated. The inner diameter guide member 133 is a coupling portion 133a coupled to the distal end of the device housing 110 and a connection guide portion 133b extending while the diameter gradually decreases to a funnel shape in the coupling portion 133a. And the nozzle guide portion 133c extending in a tubular shape from the connection guide portion 133b.

The coupling portion 133a is coupled to the outer side of the front end of the device housing 110, preferably may be detachably coupled. In the coupling portion 133a, the connection guide portion 133b is integrally extended by a predetermined distance, and the diameter is gradually reduced to extend in a funnel shape. And the nozzle guide part 133c extends in the tubular shape of the same diameter at the edge part of the connection guide part 133b. The nozzle guide portion 133c having such a configuration is inserted into the uterine inner tube 20 so that plasma energy is concentrated in the uterine inner tube 20 so that cancer cells on the endometrial tube 20 side can be effectively cured. do.

On the other hand, the outer diameter guide member 131 and the inner diameter guide member 133 described above may be integrally formed at the front end of the device housing 110, it may have a structure capable of exchange mounting by a screw fastening method. Therefore, the outer diameter guide member 131 and the inner diameter guide member 133 may be selectively employed according to the treatment area.

In addition, in the case of the plasma treatment apparatus 100 'for cervical treatment according to the second embodiment having the above configuration, as described above with reference to FIG. 5, the camera module 140 and the gas suction unit 150 are further provided. An example is shown in FIG. 8.

Referring to FIG. 8, the camera module 140 is installed in the guide part 130 ′. Preferably, the camera module 140 may be installed in the connection guide part 133b to be adjacent to the nozzle guide part 133c of the guide part 130 '.

The gas recovery part 150 includes a gas recovery nozzle 151 and a recovery path 153, and the gas recovery nozzle 151 protrudes through the connection guide part 133b to be adjacent to the nozzle guide part 133c. It should be installed as much as possible.

Referring to FIG. 9, the cervical healing plasma treatment apparatus 200 according to the third embodiment of the present invention may be provided in the device housing 201 and the device housing 201 to repair the cervical external cervix. A first plasma generating module (u-DBD) 210 and a second plasma generating module (jet) 220 for healing the endometrial canal are provided.

The first plasma generation module 210 is installed to generate a plasma in a predetermined region of the front end of the device housing 201 and the gas supply path 211 for supplying a gas toward the front end of the device housing 201 The first plasma generator 213 is provided.

The cylindrical durable structure 215 is installed inside the device housing 201 to the second plasma generating unit 223 of the second plasma generating module 220. The internal structure 215 may include a quartz tube and may further include an insulation pipe formed of an insulating material. A circular tubular electrode or a wire in the form of a wire that can supply power to the second plasma generator 223 through the inside of the insulating pipe may be installed inside the internal structure 215. In the case of a wire in the form of a wire, the gas supply path 221 is provided through the empty space between the internal structure 215 and the wire. Prepared.

The first plasma generating module 210 is installed at the front end of the device housing 201 and is installed to generate plasma at the outer portion except the center portion. The first plasma generation module 210 may have the same configuration as that of the plasma generation unit 120 described above with reference to FIGS. 2 and 3. However, since the second plasma generating module 220 is installed at the central portion of the front end of the device housing 201, the first plasma generating module 210 is positioned around the center of the second plasma generating module 220. This is installed. The plasma generated by the first plasma generating module 210 is used to treat the uterine outer tube 10.

The second plasma generation module 220 is installed inside the internal structure 215, and preferably, a so-called plasma jet for discharging atmospheric pressure plasma. Such a plasma jet can generate an atmospheric pressure plasma in a specific portion, and thus, by focusing and discharging the plasma toward the uterine endoscope 20, it can be effective in killing and healing cancer cells of the uterine endoscope 20. The second plasma generation module 220 may have a configuration of a known plasma jet, and is installed at a central portion of the first plasma generation module 210 to maintain an insulation state with the first plasma generation module 210.

An example of the second plasma generation module 220 is illustrated in FIG. 10. The illustrated second plasma generation module 220 may have a configuration in which an external ground electrode 222 and an internal electrode 224 are provided with a quartz tube 215 ′ or an insulator tube interposed therebetween. When gas is supplied to one end of the inside of the circular tube-shaped electrode 224, plasma is generated by a gap with the external ground electrode 222 at the tip portion 223a of the other end of the inner electrode 224. This configuration is formed in a thin tubular shape, and is installed inside the internal structure 215 inside the device housing 201. Therefore, the plasma jet generated at the tip of the second plasma generating module 220 may be concentrated at the center of the tip of the device housing 201 to be concentrated at the inlet side of the endometrial tube 20.

In the vicinity of the plasma jet, the plasma generated by the first plasma generator 210 is concentrated in the uterine outer tube 10 so that the cancer cells of the uterine outer tube 10 may be cured.

As described above, according to the plasma treatment apparatus for cervical cancer healing according to the third embodiment of the present invention, the so-called hybrid plasma treatment in which DBD (Dielectric Barrier Discharge) surface discharge plasma and plasma jet are mixed is used. As a device, complex plasma energy may be generated to simultaneously heal precancerous lesions of the uterine outer tube 10 and the uterine inner tube 20.

Of course, in the case of the cervical healing plasma treatment apparatus 200 according to the third embodiment, as shown in Figure 11, the camera module 140 is installed on the front end of the device housing 201, gas recovery unit 150 may have a configuration installed in the device housing 201. In this case, the gas recovery nozzle 151 of the gas recovery unit 150 is installed to protrude to the front end of the first plasma generating unit 213 as shown, or protrudes to the front end of the second plasma generating module 220. It can also be installed.

12 and 13, according to the plasma treatment apparatus 200 for treating cervical cancer according to the fourth embodiment of the present invention, a device installed in the device housing 201 and the device housing 201 is provided. The first plasma generating module 210, the second plasma generating module 220, and the plasma guide unit 230 are provided.

Here, since the first plasma generating module 210 and the second plasma generating module 220 have been described in detail with reference to FIGS. 9 and 10, further description thereof will be omitted.

The plasma guide unit 230 includes an outer diameter guide member 231 and an inner diameter guide member 233.

The outer tube guide member 231 serves to guide the plasma energy generated by the first plasma generating module 210 to the uterine outer tube 10. The outer diameter guide member 231 may have the same configuration as the outer diameter guide member 131 described above with reference to FIG. 1. That is, the outer tube guide member 231 is connected to the outer edge of the front end of the device housing 201, and extends while extending outward to support the uterine outer tube 10 so as to concentrate the plasma into the uterine outer tube 10. Play a role.

The inner diameter guide member 233 is installed at a boundary portion between the first plasma generating module 210 and the second plasma generating module 220, and has a nozzle shape having a predetermined diameter. The inner diameter guide member 233 has a diameter enough to enter into the inner diameter canal so that the plasma jet is concentrated inside the uterine inner diameter tube 20, it is preferably formed to a predetermined length. The inner diameter guide member 233 may be formed of a dielectric, and may be integrally formed by being connected to the dielectric of the first plasma generating module 210.

According to the plasma treatment apparatus 200 as shown in FIG. 9, as shown in FIG. 10, the plasma generated in each of the uterine outer tube 10 and the uterine inner tube 20 acts on each site. It can effectively treat precancerous lesions. In particular, the inner tube guide member 233 passes through the endometrial canal 20 and enters the uterus to allow the plasma to directly reach the inner precancerous lesion, thereby effectively killing and healing cancer cells.

Meanwhile, the effect of killing cervical cancer cells using plasma energy as described above, but only killing cancer cells without affecting other normal cells, is described in Application No. 10-2018-0028466 filed by the present applicant. Therefore, detailed description of the cell death effect will be omitted.

In addition, the cervical cancer healing plasma treatment apparatus 200 ′ according to the fourth embodiment may further include a camera module 140 and a gas recovery unit 150 as described above. The camera module 140 may be installed in the guide unit 230, and the gas recovery nozzle 151 of the gas recovery unit 150 may be installed to protrude toward the front end of the first plasma generation module 210.

14 and 15, the cervical cancer therapeutic plasma treatment apparatus 300 according to the fifth embodiment of the present invention includes a device housing 301 and a first plasma installed in the device housing 301. The generation module 310, the second plasma generation module 320 and the plasma guide unit 330 is provided.

Here, the device housing 301 has a tubular shape, and an internal structure 315 including a quartz tube or the like is installed therein. The first plasma generating module 310 is disposed between the internal structure 315 and the inner wall of the device housing 301 to generate plasma to the tip of the device housing 301. As described above with reference to FIG. 8, the first plasma generation module 310 preferably includes a so-called plasma jet for discharging the atmospheric plasma in a jet manner. In this case, as shown in FIG. 12, a plurality of first plasma generating modules 310 may be provided at a predetermined interval around the outside of the second plasma generating module 320. As such, the plasma jet generated through the first plasma generating module 310 is generated to the front surface of the front end of the device housing 301, and is guided by the outer diameter guide member 231 of the plasma guide unit 330 to be outside the uterus. It can be concentrated to treat the officer. Here, an insulator may be interposed between the plurality of first plasma generating modules 310.

The second plasma generation module 320 is installed inside the internal structure 315 and is installed to generate a plasma jet to its tip. The second plasma generation module 320 may be disposed in the same structure and the same position as the second plasma generation module 220 described above with reference to FIGS. 12 and 13. In addition, the plasma jet generated by the second plasma generation module 320 may be guided to be concentrated into the uterine inner canal through the inner canal guide member 233 of the plasma guide unit 330.

Since the plasma guide unit 330 has the same structure and role as the guide unit 230 described above with reference to FIG. 12, a detailed description thereof will be omitted.

According to the plasma treatment apparatus 300 having the above configuration, it is possible to heal each of the uterine inner tube and the uterine outer tube using a plasma jet.

In addition, as shown in FIG. 16, the cervical cancer healing plasma treatment apparatus 300 according to the fifth embodiment includes a camera module 140 and a gas recovery unit installed around the plurality of first plasma generating modules 310. A gas recovery nozzle 151 of 150 may be further provided. The camera module 140 and the gas recovery nozzle 151 are installed adjacent to the front end of the first plasma generating module 310.

While the invention has been shown and described in connection with preferred embodiments for illustrating the principles of the invention, the invention is not limited to the construction and operation as shown and described. Rather, those skilled in the art will appreciate that many changes and modifications to the present invention are possible without departing from the spirit and scope of the appended claims.

100,100 ', 200,200', 300 .. Plasma treatment device for cervical cancer
110,201,301. Device housing 120.Plasma generating part
130,130 ', 230..Plasma guide part 140..Camera module
150. Gas recovery unit 210, 310. First plasma generating module
220,320 .. Second Plasma Generation Module 231 ..
133,233..Inner pipe guide member

Claims (21)

A probe-type device housing capable of entering the planar cavity to heal the cervix;
A plasma generator for generating plasma energy at a tip of the device housing; And
And a plasma guide unit installed at the distal end of the device housing and guiding the plasma generated by the plasma generator to be concentrated on the cervix side. The method of claim 1, wherein the plasma guide portion,
And an outer diameter tube guide member extending and extending from an edge of the tip of the device housing to surround and support the uterine outer tube. According to claim 2, wherein the outer diameter guide member,
A coupling part coupled to a front end of the device housing; And
Plasma treatment device for cervical cancer, characterized in that it comprises; expansion ribs formed to expand in the coupling portion to surround the uterine outer tube. The method of claim 1, wherein the plasma guide portion,
Plasma treatment device for cervical cancer treatment, characterized in that it comprises an inner diameter guide member extending to gradually narrow from the edge of the front end of the device housing to guide the plasma energy to the endometrial canal. The method according to any one of claims 1 to 4,
The plasma generator is a plasma treatment device for cervical cancer, characterized in that the low temperature atmospheric dielectric barrier (DBD; Dielectric Barrier Discharge) plasma. The method according to any one of claims 1 to 4,
Plasma treatment device for cervical cancer treatment, characterized in that it further comprises a camera module installed on the front end of the device housing to photograph the site to heal. The method according to any one of claims 1 to 4,
And a gas recovery unit installed in the device housing so as to recover the gas used to generate the plasma supplied to the plasma generation unit.
A probe-type device housing that can enter the planar cavity to cure cervical cancer;
A first plasma generating module installed in the device housing to generate plasma for healing the uterine outer tube; And
And a second plasma generating module installed in the device housing to generate plasma for treating the cervical canal. The method of claim 8,
And the second plasma generating module is disposed to generate plasma energy to a central portion of the plasma generating surface generated by the first plasma generating module. The method of claim 8, wherein the first plasma generation module,
Plasma treatment device for cervical cancer treatment, characterized in that it comprises a low-temperature atmospheric dielectric barrier (DBD; plasma). The method of claim 10, wherein the second plasma generation module,
And a low temperature atmospheric plasma jet capable of intensively generating plasma at a central portion of the distal end of the device housing. The method of claim 8,
The first and second plasma generating module each of the plasma treatment device for cervical cancer, characterized in that it comprises a low-temperature atmospheric plasma jet. The method according to any one of claims 8 to 12,
And a plasma guide unit installed in the device housing to guide plasma energy generated by the first and second plasma generating modules to be concentrated on the cervix. The method of claim 13, wherein the plasma guide portion,
And an outer diameter guide member extending from the edge of the tip of the device housing to guide the plasma energy generated in the first plasma generator to the uterine outer tube to concentrate the plasma energy. The method of claim 13, wherein the plasma guide portion,
And an inner diameter guide member connected to a central portion of the distal end of the device housing to guide the plasma energy generated by the second plasma generating module to the endometrial canal. The inner diameter guide member of claim 15,
Plasma treatment device for cervical cancer treatment, characterized in that the protruding extension in the shape of a nozzle in the center of the front end of the device housing is inserted into the endometrial canal to deliver plasma energy. The method of claim 14, wherein the outer diameter guide member,
A coupling part coupled to a front end of the device housing; And
Plasma treatment device for cervical cancer, characterized in that it comprises; expansion ribs formed to expand in the coupling portion to surround the uterine outer tube. The method according to any one of claims 8 to 12,
Plasma treatment device for cervical cancer treatment, characterized in that it further comprises an internal structure installed inside the device housing to isolate the first and second plasma generating module. The method of claim 18,
The inner structure includes a quartz tube,
And a gas supply path for supplying gas to the plasma generating unit of the first plasma generating module between the quartz tube and the device housing. The method according to any one of claims 8 to 12,
Plasma treatment device for cervical cancer treatment, characterized in that it further comprises a camera module installed on the front end of the device housing to photograph the area to be treated. The method according to any one of claims 8 to 12,
And a gas recovery unit installed in the device housing so as to recover the gas used to generate the plasma supplied to the plasma generation unit.

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