KR20190064934A - Biodegradable tubes for orthodontics with heat shrinkage and a preparation method thereof - Google Patents

Abstract

The present invention relates to a wire composite for orthodontics comprising a water-soluble or biodegradable material with heat shrinkage and a method for manufacturing the same. The wire composite comprises a wire capable of securing teeth and a biodegradable tube in which the wire is placed into a hollow portion, in order to facilitate easy performance of orthodontic treatments and allow a dental resin to easily adhere to a tooth surface without using a bracket. A plurality of protrusions are formed on an inner circumferential surface or an outer circumferential surface of the biodegradable tube, and the biodegradable tube is contracted through heat to be more tightly bonded to the wire, which is an orthodontic wire rod.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to a biodegradable tube for orthodontic heat shrinking and a manufacturing method thereof,

The present invention relates to a wire composite for dental orthodontics comprising a water-soluble or biodegradable material capable of heat shrinkage and a method for manufacturing the same. More specifically, the present invention relates to a dental orthodontic wire composite which is easy to adhere to a tooth surface using a dental resin without using a bracket, And provides a wire composite for orthodontic use in which a tube of a biodegradable material can be more tightly coupled to a wire as a dental fixation wire using heat.

Generally speaking, the term "malocclusion" is collectively referred to as a non-uniform dental state of the teeth or a state in which the up and down engagement is out of the normal range, and the developmental abnormality of the jaw bone.

People with unequal teeth or malocclusion may have their mouths blocked when talking or laughing with others, and they may be passive in interpersonal relationships, making it difficult to have a decent social life. In addition, it may cause a disorder in pronunciation or masticatory function. Therefore, a corrective treatment is required, which is usually called orthodontic treatment.

A variety of orthodontic appliances have been developed and used to achieve non-uniform arrangement of teeth or malocclusion. Typical orthodontic appliances include brackets, which can be used with orthodontic wires to move teeth have.

The brackets function to guide the tooth to slide along the wire while delivering the restoring force generated by the bent wire basically in the shape of the crooked teeth to the tooth continuously, but the bracket is very inconvenient due to the relatively large and complicated structure, During treatment, the brackets are visible and the aesthetics deteriorate.

Accordingly, since the conventional orthodontic appliance includes a structure for mounting a bracket and fixing a wire, it is not only complicated in the fitting process but also causes pain during the fitting process, and is generally provided with a metal material, There is a fear that the tongue or the inner portion of the lips may interfere with the corner portion of the bracket and cause a wound.

In order to overcome this problem, an orthodontic method using a mini tube and a wire in the form of a small hollow tube is used (Patent No. 1234205). The orthodontic method using a mini tube has the following fundamental problems.

It is very difficult to insert the orthodontic wire into a mini tube having an inner diameter smaller than 0.5 mm attached to irregularly crooked teeth and it is not possible to insert the wire from the back of the neck so that the mini tube can not be used for the posterior tooth (molar) (Front teeth), and it is difficult to apply the mini tube to orthodontic wire and application area because it is applied to the desired site by combining the mini tube with the orthodontic wire. It has discomfort.

In addition, the registered patent No. 1510857 discloses a transparent correction device, which is advantageous in that it can be attached and detached and has high esthetics. However, it takes a long time to incinerate and inconvenience the transparent correction device to be manufactured several times Still have problems.

Therefore, it is necessary to develop a member for orthodontic treatment which can shorten the period of orthodontic treatment of the patient, fix it well to the orthodontic wire, and resist the resin or other etching and bonding agent, .

Patent No. 1234205 Patent No. 1510857

The present invention provides a member for orthodontic treatment including a water-soluble or biodegradable material capable of heat shrinkage. It is easy to adhere to a tooth surface by using a dental resin instead of using a bracket, .

Another object of the present invention is to provide a method of manufacturing an orthodontic orthodontic appliance, which comprises dissolving or biodegrading a water-soluble or biodegradable material for orthodontic application applied to a dental orthodontic wire after a predetermined period of time to form a clearance between the dental orthodontic wire and the resin The present invention is to provide a member for orthodontic treatment which is easy to move and correct the teeth during an orthodontic procedure due to the formation of such a moving space by allowing the teeth to slide while moving along the orthodontic wire.

It is another object of the present invention to provide convenience during the orthodontic treatment procedure, in which the heat shrinkage characteristic of the orthodontic member closely contacts the orthodontic wire, and the wire, which is a dental orthodontic wire, The present invention is to provide a member for orthodontic treatment which is in close contact so as not to be dislodged and has increased convenience for orthodontic treatment which can be easily applied to the teeth.

Further, the orthodontic tube according to the present invention, which is a member for orthodontic treatment according to the present invention, includes a protruding structure protruding to the outside or inside of the tube body to enhance adhesion to the outside resin (outer protrusion) It is a movement path that catches wire rod and passes water or water to the inside of tube and promotes hydrolysis by water or water to make gap between dental orthodontic wires and resin more quickly (internal projection) Member.

A wire composite for orthodontic treatment according to an embodiment of the present invention includes: a wire capable of fixing a tooth; And a tube having a hollow portion and into which the wire is inserted, wherein the tube is a water-soluble or biodegradable material, and a plurality of protrusions are formed on an inner circumferential surface or an outer circumferential surface of the tube. If necessary, a plurality of protrusions may be formed simultaneously on the inner circumferential surface of the hollow portion of the tube and the outer circumferential surface of the tube.

The cross section of the wire is circular, elliptical or polygonal, the cross section of the hollow section of the tube is the same as the cross section of the wire, and the cross section of the hollow section of the tube is larger than the cross section size of the wire.

The protrusions formed on the outer circumferential surface or the inner circumferential surface of the tube preferably have a height of 0.05 to 0.1 mm, a width of 0.05 to 0.1 mm, and more preferably 0.1 to 0.5 mm.

Preferably, the tube is formed of a water-soluble or biodegradable polymer material. More specifically, the tube may be formed of a polymer such as polycaprolactone (PCL), polylactic acid (PLA), polyglycolic acid (PGA), polylactide- (PLGA), polydioxane (PDO), polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), hyaluronic acid, collagen, chitosan, dextran, alginate, starch and cellulose And the weight average molecular weight is preferably in the range of 1,000 to 1,000,000.

Another embodiment of the present invention is a method of manufacturing a wire composite for orthodontics, comprising: preparing a tube having a hollow portion by molding a water-soluble or biodegradable material; Positioning a wire in the hollow of the tube; And heating the tube to shrink the tube to adhere to and secure the wire.

The step of preparing the tube having the hollow portion may further include forming a hollow portion in the tube, and then forming a protrusion on the inner circumferential surface or the outer circumferential surface of the tube having the hollow portion.

 In the step of adhering and fixing the tube to the wire, it is preferable to heat the tube at a temperature not lower than the glass transition temperature of the material forming the tube, more specifically, within a temperature range of about 40 to 60 DEG C for about 10 seconds .

The thus prepared wire composite for orthodontic treatment is preferably further subjected to a step of enclosing the wire and the tube using a resin which is an acrylic polymer capable of being photopolymerized so as to be attached to a tooth.

The orthodontic tube according to the present invention is characterized in that it has water-soluble or biodegradable characteristics, has a diameter larger than the diameter of the wire, which is the orthodontic wire, and has an advantage that it can be easily manipulated. And has the advantage of being compatible with the orthodontic wire having various diameters.

That is, the orthodontic member including the water-soluble or biodegradable material according to the present invention can be easily applied to orthodontic wires having various diameters (diameters), and can be shrunk when heat is applied to the orthodontic wires The dentition phenomenon can be effectively reduced when densely contacted and applied to the teeth.

In addition, the orthodontic member according to the present invention can be easily adhered or fixed to the tooth surface through the dental resin. In addition to simplifying the conventional bracket and the various orthodontic appliances, the adhesive and the adhesive for etch correction It is possible to provide a member for orthodontic treatment which is resistant to a substance used in the orthodontic treatment and can simplify the orthodontic treatment.

In addition, after the orthodontic treatment is performed using the orthodontic member including the water-soluble or biodegradable material according to the present invention, the water-soluble or biodegradable material is dissolved or biodegraded after a predetermined period of time and the orthodontic wire A gap can be formed between the resin and the tooth, and the tooth can be moved while sliding along the wire for orthodontic treatment. Therefore, it is possible to provide a member for orthodontic correction excellent in correcting effect due to easy movement of teeth.

In addition, the dental orthodontic member including the water-soluble or biodegradable material according to the present invention can firmly fix the dental orthodontic wire and the resin between the dental orthodontic appliance due to heat shrinkage at the initial stage of the orthodontic treatment, The water or biodegradable material is decomposed to form a gap between the dental orthodontic wire and the resin, thereby facilitating the movement of the teeth, thereby shortening the period of orthodontic treatment.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 schematically illustrates an embodiment of a wire composite for orthodontics comprising an aqueous or biodegradable material according to the present invention ((a): arched, (b): straight).
Figure 2 schematically illustrates a cross-sectional structure of a wire composite for orthodontics according to various embodiments of the present invention
3 schematically illustrates the heat shrinkage process of the biodegradable tube constituting the wire composite for orthodontics of the present invention.

Hereinafter, the present invention will be described in detail with reference to embodiments and drawings of the present invention. It will be apparent to those skilled in the art that these embodiments are provided by way of illustration only for the purpose of more particularly illustrating the present invention and that the scope of the present invention is not limited by these embodiments .

Also, unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains and, where contradictory, Will be given priority.

In order to clearly illustrate the claimed invention, parts not related to the description are omitted, and like reference numerals are used for like parts throughout the specification. And, when a section is referred to as "including " an element, it does not exclude other elements unless specifically stated to the contrary.

The wire composite for orthodontic treatment according to the present invention can be fixed to the teeth through the dental resin instead of the bracket in the orthodontic treatment procedure so that the orthodontic treatment can be performed. As shown in FIG. 1, It is preferably used in combination with a tube of biodegradable material.

The cross-sectional structure of the orthodontic wire composite can be implemented in various forms. A typical example is also shown in Fig. 2 in which biodegradable tubes 20 (a, b) are combined with wires 10 having a circular cross section, Biodegradable tubes (c, d) that are coupled to the wire are schematically shown.

The inner circumferential surface of the through hole of the biodegradable tube or the outer circumferential surface of the tube may include protrusions as shown in FIG. 2. It is also possible that protrusions are simultaneously formed on the inner circumferential surface and the outer circumferential surface.

The protrusions formed on the inner circumferential surface of the through hole of the biodegradable tube provide a space in which water, saliva or saliva can effectively penetrate between the wire rod and the biodegradable tube when attached to the teeth together with the wire rod, And the protrusion formed on the outer circumferential surface of the tube can perform a function of increasing the contact area so that the following resin and the tube can be more firmly coupled to each other.

The protrusions preferably have a height of 0.05 to 0.1 mm, a width of 0.05 to 0.1 mm, and a thickness of 0.1 to 0.5 mm. When the height is too low or the width is too narrow, The function as an outer projection can not be sufficiently exerted, and if the height is too large, the structural stability may be lowered.

Even when the width of the projection is too wide, it is also difficult to effectively perform the function as the outer projection or the inner projection of the tube.

 It is preferable that the wire rod is inserted and bonded through the through hole of the biodegradable tube having the protrusions, and then heated to shrink the biodegradable tube.

FIG. 3 schematically illustrates the heat shrinking process of the biodegradable tubes a, b, c, and d according to the various embodiments shown in FIG. 2, As shown in Fig.

The heat shrinkage process can be performed by heating to a temperature not lower than the glass transition temperature of the biodegradable polymer constituting the biodegradable tube, preferably to a temperature range of about 40 to 60 DEG C for about 10 seconds or less .

Preferably, the tube is formed of a water-soluble or biodegradable polymer material. More specifically, the tube may be formed of a polymer such as polycaprolactone (PCL), polylactic acid (PLA), polyglycolic acid (PGA), polylactide- (PLGA), polydioxane (PDO), polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), hyaluronic acid, collagen, chitosan, dextran, alginate, starch and cellulose And the weight average molecular weight of such a biodegradable polymer is preferably in the range of about 1,000 to 1,000,000 in consideration of the biodegradation rate.

More preferably, PLA, PGA, or PLGA having a high heat shrinkage ratio can be used, and heat shrinkage of the tube can be induced by heating to a temperature of about 40 to 50 ° C.

Another embodiment of the present invention is a method for producing an orthodontic wire composite.

First, a water-soluble or biodegradable polymer material is molded into a tube having a hollow portion. The water-soluble or biodegradable polymer material may be prepared by extrusion or injection molding.

In this manufacturing process, the protruding portion may be formed at the same time in the extrusion or injection process. Alternatively, after the tube having the hollow portion is manufactured, the protruding portion may be processed into a desired size and shape.

The wire to be used for orthodontic orthodontic wire is connected to the hollow region of the tube including the hollow portion. The wire to be used at this time may be a conventional orthodontic wire. However, ; A protective coating layer formed on said tooth color impermeable layer; And a water-soluble or biodegradable coating layer formed on the protective coating layer. The cross section of the wire may be circular, oval or polygonal.

The tooth color rendering layer, the protective coating layer, and the water-soluble or biodegradable coating layer constituting the orthodontic wire according to the present invention are preferably conformally formed on the surface of the wire, and the protective coating layer and the water-soluble or biodegradable The coating layer may be formed by a method of carrying, spraying, extruding or extruding.

It is preferable that the tooth color rendering layer is formed by a method selected from the group consisting of titanium and silver alloy, zirconium and silver alloy, molybdenum and silver alloy, tantalum and silver alloy by arc ion plating, At least one of polyethylene (PE), polypropylene (PP), polystyrene (PS), polyvinyl chloride (PVC), polymethyl methacrylate (PMMA), polyethylene terephthalate (PET) and polyurethane (PLGA), polyglycolic acid (PGA), polylactic coccolyric acid (PLGA), polyacrylic acid (PLGA), polyacrylic acid (PDA), polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), hyaluronic acid, collagen, chitosan, dextran, alginate, starch and celluloses, medium The weight average molecular weight is preferably in the range of 1,000 to 1,000,000.

The biodegradable tube can be brought into close contact with and fixed to the wire by placing the wire as the wire for orthodontic treatment in the hollow portion of the biodegradable tube and then heating and shrinking the biodegradable tube.

The step of adhering and fixing the tube to the wire may be performed by short-time heating to a temperature not lower than the glass transition temperature of the material forming the tube. The temperature is in the range of about 40 to 60 DEG C, preferably about 40 to 50 DEG C It can be instantaneously heated for a time of about 10 seconds or less.

The orthodontic wire composite manufactured in this way can be further attached to the tooth by further adding a step of surrounding the wire and the tube by using a resin which is an acrylic polymer capable of being photopolymerized so as to be attached to the tooth .

The wire composite for dental orthodontics according to the present invention has improved dissolution resistance for etching, bonding and resin used in orthodontic treatment, and is used as an initial treatment for shortening the orthodontic treatment period using transparent correction as a procedure before transparent correction And also has the advantage of being able to perform sufficient orthodontic treatment with the resin without the bracket used in the conventional orthodontic treatment procedure.

Hereinafter, the wire composite for orthodontics will be described in more detail with reference to a specific embodiment of the present invention.

[Example 1]

First, a biodegradable tube was prepared using PLGA having a weight average molecular weight of about 80,000 to 100,000 as a raw material, and then bonded to a wire. The combined PLGA tubes and wires were shrunk by heating to a temperature of 45 DEG C for 7 seconds.

5 (a) is a cross-sectional view of a wire, and FIG. 5 (b) is a cross-sectional view of a heat- Fig. 5 (c) is a photograph of a section of a tube and a wire after heat shrinkage. Fig.

FIG. 6 shows the results of actual measurement of the inner diameter change of the PLGA tube before and after the heat shrinkage. It can be confirmed that the inner diameter of the tube decreased by about 40% from about 1 mm to 0.6 mm, , Which means that the PLGA tube is thermally shrunk and completely adhered to the wire inserted into the hollow portion.

From these experimental results, it can be seen that the heat shrinkage of the biodegradable tube can be controlled by appropriately controlling the thickness of the wire inserted into the biodegradable tube.

[Example 2]

Using the Digital Fore Gauges (Model No. DS2-4, Digital Force Gauge and push pull gauge Imada japan) shown in Fig. 7 to confirm the adhesive strength of the thermally contracted orthodontic wire composite to the resin, heat shrinkage The adhesive strength between the tube and the resin before and after was measured.

A wire as an orthodontic wire was inserted into a biodegradable tube in the same manner as in Example 1, and a powder of PMMA and a methyl methacrylate (MMA) monomer were mixed with each other so that the orthodontic wire could be attached to teeth A dental resin, which was an acrylic resin, was applied to the area where the biodegradable tube and the wire were combined, and was shrunk by heating at 45 캜 for 7 seconds.

Fig. 8 shows the state before and after the heat shrinkage (Fig. 8 (a)) and after (Fig. 8 (b)), and shows the adhesion of the biodegradable tube before and after the heat shrinkage measured using the tester shown in Fig. The strength change is shown in Fig.

As can be seen from the results of FIG. 9, it can be seen that the adhesive strength between the tube and the resin after heat shrinkage significantly increased compared with that before heat shrinkage.

10: Wire for orthodontic wire
20: Biodegradable tube

Claims (10)

In the orthodontic wire composite,
A wire to fix the tooth; And
And a tube including a hollow portion and into which the wire is positioned,
The tube is a water-soluble or biodegradable material,
Wherein a plurality of projections are formed on an inner circumferential surface or an outer circumferential surface of the tube.
The method according to claim 1,
Wherein the wire has a circular, oval or polygonal cross section,
Wherein a cross-section of the hollow portion of the tube is the same as that of the wire,
Characterized in that the size of the hollow section of the tube is greater than the cross-sectional size of the wire.
The method according to claim 1,
The protrusion formed on the outer circumferential surface or the inner circumferential surface of the tube has a height of 0.05 to 0.1 mm and a width of 0.05 to 0.1 mm.
The method according to claim 1,
Wherein the tube has a thickness of 0.1 to 0.5 mm.
The method according to claim 1,
The tube may be made from a material selected from the group consisting of polycaprolactone (PCL), polylactic acid (PLA), polyglycolic acid (PGA), polylactic coccolyric acid (PLGA), polydioxane (PDO), polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), hyaluronic acid, collagen, chitosan, dextran, alginate, starch and celluloses, and having a weight average molecular weight of 1,000 to 1,000,000 Wire composite.
A method of manufacturing an orthodontic wire composite,
Preparing a tube having a hollow portion by molding a water-soluble or biodegradable material;
Positioning a wire in the hollow of the tube; And
And heating the tube to shrink the tube to adhere to and secure the wire.
The method according to claim 6,
The step of preparing the tube having the hollow portion includes:
After a hollow portion is formed in the tube,
Further comprising the step of forming protrusions on the inner circumferential surface or the outer circumferential surface of the tube having the hollow portion formed therein.
The method according to claim 6,
The tube may be made from a material selected from the group consisting of polycaprolactone (PCL), polylactic acid (PLA), polyglycolic acid (PGA), polylactic coccolyric acid (PLGA), polydioxane (PDO), polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), hyaluronic acid, collagen, chitosan, dextran, alginate, starch, and celluloses, and has a weight average molecular weight ranging from 1,000 to 1,000,000 Wherein said wire composite is made by a method comprising the steps of:
9. The method of claim 8,
And heating the tube at a temperature not lower than the glass transition temperature of the material forming the tube in the step of tightly adhering and fixing the tube to the wire.
The method according to claim 6,
Between the step of positioning the wire in the hollow portion of the tube and the step of sticking and fixing to the wire,
And encapsulating the wire and the tube using a resin that is an acrylic polymer that can be photopolymerized so that it can be attached to a tooth.

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